Abstract:
:Th2 cells have been shown to exert cell-mediated immune responses in vitro; therefore, the present study was conducted to investigate the cellular mechanisms of the long-term survival of cardiac xenografts by measuring cytokine production from recipient lymphocytes. Xenogeneic heart grafts from Lewis rats were transplanted into C57BL/6 mice, and the recipients were intravenously injected with H57-597 at the time of transplantation. The production of Th1 cytokines, namely, interleukin (IL)-2 and interferon (IFN)-gamma, and Th2 cytokines, namely, IL-4 and IL-10, from mixed lymphocyte culture cells was assayed by enzyme-linked immunosorbent assay. Splenocytes from the xenograft recipients treated with H57-597 produced significantly lower levels of IL-2, IFN-gamma, IL-4, and IL-10 than those from the untreated recipients, 100 days after transplantation. The findings of this study indicate that the long-term survival of cardiac xenografts induced by H57-597 is mediated by the inhibition of Th0, or both the Th1 and Th2 response.
journal_name
Surg Todayjournal_title
Surgery todayauthors
Kishimoto K,Furukawa K,Ashizuka S,Sawada T,Ayabe Hdoi
10.1007/s005950050034subject
Has Abstractpub_date
2000-01-01 00:00:00pages
159-62issue
2eissn
0941-1291issn
1436-2813pii
10.1007/s005950050034journal_volume
30pub_type
杂志文章相关文献
SURGERY TODAY文献大全abstract::To explore the anatomical repositioning of the middle lobe following right upper (RU) lobectomy, we measured the lobar volumes of the lung and the branching angles of the airway, and defined their changes after RU lobectomy in a rabbit model. Groups A1 (n = 10) and A2 (n = 10) were control groups and groups B1 (n = 10...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950050122
更新日期:1998-01-01 00:00:00
abstract::We report the successful management of multiple small-bowel perforations caused by cytomegalovirus (CMV) infection in a 60-year-old man, 1 day after CHOP (cyclophosphamide/doxorubicin/vincristine/prednisone) therapy induction for malignant lymphoma. Emergency laparotomy was performed for perforative peritonitis, but w...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-006-3274-x
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:This study was conducted to determine whether establishing the proximal resection line using India ink tattooing can ensure safe resection margins during totally laparoscopic distal gastrectomy. METHODS:This retrospective study included 81 patients who underwent totally laparoscopic distal gastrectomy for gast...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-020-02057-9
更新日期:2021-01-01 00:00:00
abstract::By employing three-dimensional computed tomography (CT) for portography, we analyzed the portal vein changes during the initial stage after a pancreaticoduodenectomy (PD), which seemed to affect postoperative complications. Four patients underwent PD without portal vein reconstruction with a standard radical lymph nod...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF02483962
更新日期:1998-01-01 00:00:00
abstract:PURPOSE:We investigated the predictive indicator for a good prognosis of surgical resection for liver metastasis of colorectal cancer. METHOD:Between 1990 and 2009 at our institute, 117 patients underwent 132 hepatic resections for liver metastasis of colorectal cancer. The clinical, pathological, and outcome paramete...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-013-0699-x
更新日期:2014-07-01 00:00:00
abstract::Solitary fibrous tumors (SFTs) develop most commonly in the pleura, although they have occasionally been reported to arise in the pelvic cavity. We report a case of an SFT presenting as a painless nodule in the pelvis of a 56-year-old woman. Histologically, the tumor was composed of spindle-shaped cells arranged witho...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-010-4535-2
更新日期:2011-11-01 00:00:00
abstract::The relationship between histological factors, including neural invasion (NI), and survival rates in patients with Borrmann type IV diffuse invasive gastric cancer was examined to determine the significance of NI as a prognostic factor. NI was studied histochemically in 75 patients who underwent resection after 1982, ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF02384978
更新日期:1997-01-01 00:00:00
abstract::A 53-year-old woman who had end-stage renal disease and hypertension presented with back pain. Chest radiographs and chest computed tomography (CT) showed right pleural effusion with bilateral pleural masses. The patient underwent video-assisted thoracoscopic surgery (VATS) for a biopsy of the right pleural mass and f...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-007-3709-z
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:This study was performed to clarify the clinical features of ischemic colitis (IC) after colorectal cancer surgery. METHODS:This study retrospectively reviewed the medical records of 35 patients with IC. Patients were divided into two groups: those who had undergone colorectal cancer surgery (POIC group, n = 1...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-013-0661-y
更新日期:2014-06-01 00:00:00
abstract::A 58-year-old female patient presented with the sudden onset of left upper quadrant pain. The physical examination revealed the presence of shock status. Abdominal computed tomography revealed splenomegaly with a huge mass inside the spleen, and massive fluid collection in the abdominal cavity. After splenic artery em...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-010-4353-6
更新日期:2011-06-01 00:00:00
abstract::Aneurysmal bone cysts (ABC) are rare, especially in the ribs. This lesion is considered to be a benign process, which is usually found in children and young adults. This case, however, concerns a 71-year-old patient, the oldest patient hitherto reported in Japan, and also as old as in any other published case report w...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-005-3068-6
更新日期:2005-01-01 00:00:00
abstract::This report describes the successful treatment of quadruple cancer including Bowen's disease in a 71-year-old man who had been given injections of salvarsan, an arsenic compound, for syphilis more than 40 years earlier. Resection of a skin lesion on his chest subsequently confirmed a diagnosis of Bowen's disease, 3 ye...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF01367469
更新日期:1994-01-01 00:00:00
abstract::Although laparoscopic surgery for rectal cancer has been gaining acceptance with the gradual accumulation of evidence, it remains a technically demanding procedure in patients with a narrow pelvis, bulky tumors, or obesity. To overcome the technical difficulties associated with laparoscopic rectal dissection and trans...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-015-1195-2
更新日期:2016-06-01 00:00:00
abstract::Three patients were treated for coronary artery-pulmonary artery fistula. Each was asymptomatic due to a coronary artery fistula. There was one instance each of myocardial infarction, mitral stenosis and a large closed ruptured aneurysm including a thrombus. All the fistulas were comprised of several small plexiform a...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311346
更新日期:1992-01-01 00:00:00
abstract:PURPOSE:Esophageal achalasia can be roughly divided into non-sigmoid and sigmoid types. Laparoscopic surgery has been reported to be less than optimally effective for sigmoid type. The aim of this study was to examine the impact of the esophageal flexion level on the clinical condition and surgical outcomes of patients...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-017-1519-5
更新日期:2017-11-01 00:00:00
abstract::In a 61-year-old woman who underwent extensive retroperitoneal lymph node dissection for rectal cancer, postoperative chylous ascites developed. The site of the lymphatic leak was evident on the lymphangiogram with lipiodol taken prior to the surgical repair of the leak, and another site seen on the intraoperative lym...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00311375
更新日期:1993-01-01 00:00:00
abstract:PURPOSE:We investigated the effects of thrombopoietin (TPO) on platelet counts and liver regeneration after partial hepatectomy in rats. METHODS:We performed 70% partial hepatectomy on 60 rats given either TPO or a vehicle (controls). The rats were killed 6 h, 24 h, 72 h, or 168 h after the procedure, and we examined ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-008-4054-6
更新日期:2009-01-01 00:00:00
abstract::We report a rare case of hepatic inflammatory pseudotumor (IPT) after a hepatitis B virus (HBV) infection. Early contrast enhancement on computed tomography (CT) with a washout phenomenon at the delayed phase, and depleted Kupffer cell function on superparamagnetic iron oxide (SPIO)-enhanced magnetic resonance imaging...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-006-3306-6
更新日期:2006-01-01 00:00:00
abstract::We report a case of primary malignant melanoma (MM) of the stomach. The patient, a 73-year-old man, was referred to our hospital for investigation of an elevated lesion in the stomach, detected by gastroscopy. On admission, physical examinations and laboratory data were unremarkable. Gastroscopy revealed a pigmented, ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-011-0077-5
更新日期:2012-01-01 00:00:00
abstract:PURPOSE:We evaluated the safety and efficacy of adult-to-adult right-lobe living donor liver transplantation (ARL-LDLT) in HBV-related benign liver disease recipients with high model for end-stage liver disease (MELD) scores. METHODS:The subjects of this study were 70 adult patients who underwent ARL-LDLT and 191 who ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-013-0539-z
更新日期:2013-09-01 00:00:00
abstract::We report herein the rare case of a 15-year-old girl with chronic appendicitis in whom the appendix was clearly depicted by a barium enema (BE) examination. The patient presented with a 4-month history of diffuse abdominal pain and tenderness in the lower abdomen. Neither computed tomography nor ultrasonography showed...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/BF02385810
更新日期:1997-01-01 00:00:00
abstract:PURPOSE:We conducted this retrospective cohort study to evaluate which preoperative comorbidities and their combinations are most strongly associated with postoperative complications after gastrectomy. METHODS:We collected data on 214 consecutive patients who underwent gastrectomy for gastric cancer. Preoperative como...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-015-1175-6
更新日期:2016-02-01 00:00:00
abstract::From August 1986 to February 2000, three patients were given a pericardial-peritoneal window using a subxiphoidal approach, for pericardial effusion associated with chronic exudative pericarditis. Complete drainage without recurrence was achieved in two patients with a large pericardial-peritoneal window (4 cm diamete...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950200064
更新日期:2002-01-01 00:00:00
abstract::A 4-year-old boy was diagnosed as having a chromosomal abnormality with trisomy 3p associated with a secundum atrial septal defect and a cleft of the anterior mitral leaflet. His craniofacial features showed microcephaly, micrognathia, ocular hypertelorism associated with epicanthus, and low-set ears. Moderate mental ...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/BF00312096
更新日期:1996-01-01 00:00:00
abstract::When a patient with Ehlers-Danlos syndrome (EDS) presents with a vascular emergency, performing life-saving surgery can be difficult because of the profound fragility of the arterial tissue. We report the case of a 27-year-old woman with EDS in whom a spontaneous arterial rupture was successfully treated with transcat...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-003-2634-z
更新日期:2004-01-01 00:00:00
abstract:PURPOSE:To minimize the parietal trauma associated with multiple surgical access sites, single-incision laparoscopic surgery for colectomy has been emerging with the improvements in instrumentation and surgical techniques. The purpose of this study was to compare the clinicopathological outcomes between single-incision...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-015-1154-y
更新日期:2016-03-01 00:00:00
abstract:PURPOSE:Postoperative bowel infarction is a major contributing factor to the high mortality rate associated with acute thromboembolism of the superior mesenteric artery (SMA). This study was conducted to evaluate the prophylactic role of thrombectomy to prevent postoperative mesenteric infarction. METHODS:An autologou...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s005950200028
更新日期:2002-01-01 00:00:00
abstract::For vascular occlusive disease, an autologous vein graft is the most suitable conduit for arterial reconstruction. Intimal hyperplasia, resulting from the migration and proliferation of vascular smooth muscle cells, is a major obstacle to patency after vein grafting. The degree to which the function of nitric oxide (N...
journal_title:Surgery today
pub_type: 杂志文章,评审
doi:10.1007/s00595-013-0555-z
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:We attempted to identify the factors related to an early restoration of the exercise capacity after lung resection. METHODS:Major lung resection was performed in 164 patients. Exercise testing and spirometry were performed before surgery, and 2 weeks and 1 month afterward. During exercise, the maximum oxygen u...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-010-4441-7
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:The aim of this study was to analyze the management of enteroatmospheric fistulae (EAF) in an open abdomen using vacuum-assisted closure (VAC) therapy. METHODS:Eighteen patients (ten male/eight female) were treated in our surgical department for the management of EAF. VAC therapy was used to manage both comple...
journal_title:Surgery today
pub_type: 杂志文章
doi:10.1007/s00595-014-1020-3
更新日期:2015-09-01 00:00:00