Abstract:
:Transient pancytopenia preceding childhood acute lymphoblastic leukemia (ALL) is an unfrequent but well-known event. The association of this preleukemic syndrome with hepatitis is extremely rare, with only two such cases having been published in the literature. We report the case of a 16-year-old boy who was diagnosed with B-cell type ALL that was preceded by transient pancytopenia with absent hemopoietic cells in the bone marrow following a seronegative hepatitis episode. The clinical, morphologic and immunophenotypic features of this patient are described and the literature on this preleukemic syndrome reviewed, with special emphasis being made on its differential diagnosis with hepatitis-associated aplastic anemia.
journal_name
Haematologicajournal_title
Haematologicaauthors
Rafel M,Cobo F,Cervantes F,Bosch F,Campo E,Montserrat Esubject
Has Abstractpub_date
1998-06-01 00:00:00pages
564-6issue
6eissn
0390-6078issn
1592-8721journal_volume
83pub_type
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