Sensitivity of mouse lymphoid and nonlymphoid organs to Silesian air pollutants.

Abstract:

:The toxic effect of Silesian air pollutants to mouse organs was examined. Histological changes were found in the examined lymphoid organs (thymus, spleen) as well nonlymphoid organs (liver, kidneys). The alterations in weight indexes of lymphoid organs were also observed. Considerable changes in cellularity, weight index, and histology of the thymus in the mice exposed to air pollutants suggest the atrophy of this organ, which may lead to extrathymic T-cell differentiation and even acceleration of thymocytes maturation, which may lead to certain allergic or auto-immune pollutants of all investigated mouse organs in the following order: thymus, liver, kidneys, and spleen.

journal_name

Ecotoxicol Environ Saf

authors

Kozlowska E,Kopeć-Szlezak J,Drela N,Michur H,Izdebska-Szymona K

doi

10.1006/eesa.1996.1513

subject

Has Abstract

pub_date

1997-06-01 00:00:00

pages

10-6

issue

1

eissn

0147-6513

issn

1090-2414

pii

S0147651396915134

journal_volume

37

pub_type

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