Cerebral blood flow in children with spontaneous occlusion of the circle of Willis (moyamoya disease): comparison with healthy children and evaluation of annual changes.

Abstract:

:Changes in the mean cerebral blood flow (mCBF) with growth in normal children (1-20 years old) were evaluated, and compared to serial mCBF changes in children with spontaneous occlusion of the circle of Willis (moyamoya disease) after vascular reconstructive surgery. mCBF gradually decreased with growth in control children. Preoperative mCBF was similar or decreased in moyamoya disease patients with transient ischemic attack, and slightly decreased in those with cerebral infarction. Postoperative mCBF gradually decreased similarly to physiological changes with growth in controls. These results suggest that changes with age should be considered when preoperative and long-term cerebral hemodynamics are evaluated in children with moyamoya disease.

authors

Kuroda S,Kamiyama H,Abe H,Yamauchi T,Kohama Y,Houkin K,Mitsumori K

doi

10.2176/nmc.33.434

subject

Has Abstract

pub_date

1993-07-01 00:00:00

pages

434-8

issue

7

eissn

0470-8105

issn

1349-8029

pii

JST.Journalarchive/nmc1959/33.434

journal_volume

33

pub_type

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