Abstract:
OBJECTIVE:The purpose of this study was to compare white matter maturation as demonstrated with diffusion-weighted MRI and with myelin-sensitive histological staining. MATERIALS AND METHODS:The diffusion-, T1-, and T2-weighted SE MRI at 4.7 T was performed weekly in a total of 16 rat pups, aged from 5 days to 8 weeks, 2 animals evaluated per week. Heavily diffusion-weighted sequences were obtained with the diffusion-sensitizing gradient switched alternately in two orthogonal directions. To enhance signal intensity of anisotropic structures, a synthesized image (referred to as the "anisotropy index map") was constructed from the ratio of pairs of images acquired with diffusion sensitization of identical magnitude but orthogonal direction sensitivity. The anisotropy index maps were used for comparison with T1-weighted and heavily T2-weighted SE sequences and histological sections, respectively. RESULTS:The first evidence of diffusion anisotropy on anisotropy index maps preceded initial myelin as well as neurofibril staining by 5-12 days and T2 shortening by 2 weeks. The T1-weighted sequences did not yield visible changes and were not helpful for the assessment of ongoing white matter maturation in this model. CONCLUSION:Magnetic resonance imaging signal intensity changes based on anisotropic water diffusion were demonstrated in regions of unmyelinated cerebral white matter tracts of albino rat pups before the onset of histologically detectable myelin. The ability of in vivo mapping of premyelinating white matter maturation indicates a new diagnostic use of MRI in evaluating cerebral white matter maturation.
journal_name
J Comput Assist Tomogrjournal_title
Journal of computer assisted tomographyauthors
Wimberger DM,Roberts TP,Barkovich AJ,Prayer LM,Moseley ME,Kucharczyk Jdoi
10.1097/00004728-199501000-00005subject
Has Abstractpub_date
1995-01-01 00:00:00pages
28-33issue
1eissn
0363-8715issn
1532-3145journal_volume
19pub_type
杂志文章abstract::Cervical spinal epidural hematoma is a rare cause of acute neurologic syndromes including paralysis of various types. Although devastating, it can be successfully treated surgically if recognized early. We report two cases of spontaneous cervical epidural hematoma diagnosed by computed tomography, the first with a pla...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1984-04-01 00:00:00
abstract:OBJECTIVE:To compare examination volume and diagnostic yield of computed tomography (CT) pulmonary angiography (CTPA) and ventilation-perfusion (V/Q) scintigraphy for detection of suspected pulmonary embolism (PE) in emergency department patients. METHODS:Every CTPA and V/Q scan result for emergency department patient...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e31812e6af3
更新日期:2008-05-01 00:00:00
abstract::Four patients (three with hepatocellular carcinoma and one with colorectal carcinoma metastatic to the liver) previously treated with chemotherapy or radiotherapy or both in an attempt to reduce tumor bulk prior to surgical resection were examined by CT angiography (CTA). Areas of abnormal enhancement and irregular ve...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198807000-00007
更新日期:1988-07-01 00:00:00
abstract::Vasculitis of the testis, although common pathologically, has been difficult to diagnose clinically and to detect noninvasively. This report describes the added benefit of MR imaging in directing clinical management in a patient where the first manifestation of vasculitis was scrotal pain and swelling. This subject wa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199105000-00033
更新日期:1991-05-01 00:00:00
abstract::We describe a case of a ruptured gravid uterus, secondary to motor vehicle accident, in a 20-year-old woman. Maternal and fetal injuries associated with blunt trauma are described along with the use of CT in pregnant patients. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199103000-00030
更新日期:1991-03-01 00:00:00
abstract::This is the seventh and last in a series of studies related to procedure-oriented joint anatomy. This article reviews the anatomy of the foot and its relationship to procedures in the clinical setting with or without ultrasound guidance. Anatomically correct axial schematics allow injections to be envisioned relative ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0000000000000165
更新日期:2015-01-01 00:00:00
abstract:OBJECTIVES:The objective of this study was to assess the objective and subjective qualities of the contrast-enhanced 4-dimensional dual-energy computed tomography using adaptive statistical iterative reconstruction (ASiR) and ASiR-V. METHODS:The virtual monochromatic images at 60 keV were reconstructed using filtered ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000942
更新日期:2021-01-01 00:00:00
abstract::Present popular computed tomography (CT) algorithms reconstruct an object from the ray measurements lying on a set of parallel planes. This paper presents an algorithm that can also utilize "cross-plane" rays (i.e., rays that cross through many planes) to reconstruct the object. In this reconstruction algorithm, the r...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197906000-00015
更新日期:1979-06-01 00:00:00
abstract::Computed tomography (CT) findings in hydatid disease (echinococciasis) of the liver are described. Disease was caused by Echinococcus granulosus (n = 8) or E. alveolaris (n = 5), respectively. The CT appearance of these two types of echinococciasis is quite different; in disease caused by E. granulosus the CT appearan...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-197811000-00018
更新日期:1978-11-01 00:00:00
abstract::A case of Ebstein anomaly in a 2-day-old newborn is presented. The complementary roles of two-dimensional Doppler echocardiography and magnetic resonance imaging in managing this cardiac malformation are emphasized. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199009000-00032
更新日期:1990-09-01 00:00:00
abstract::Most renal metastases are asymptomatic, occur with widespread metastatic disease, and are too small to be detected with computed tomography (CT). Rarely they form large masses. These are typically angiographically hypovascular and show only minimal CT contrast enhancement. Renal carcinoma as a second primary malignanc...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198306000-00011
更新日期:1983-06-01 00:00:00
abstract::This report describes the imaging findings of the first reported case of a bronchobiliary fistula that developed as a complication of liver transplantation. The diagnosis was confirmed by the aspiration of bile from the bronchus. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000131583.52386.cf
更新日期:2004-09-01 00:00:00
abstract:OBJECTIVE:To verify the earliest detectability of liver metastases in patients who underwent serial multidetector computed tomography (MDCT) examinations. METHODS:We selected 12 patients with known primary cancer who underwent 4 or more contrast-enhanced, 4-detector MDCTs. When metastases had been reported, an evaluat...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200605000-00006
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVES:Pelvic organ prolapse is a common debilitating condition affecting women. Cross-sectional imaging with magnetic resonance imaging (MRI) depicts pelvic floor anatomy as well as organ prolapse and can complement or replace fluoroscopy. Occasionally, patients cannot tolerate MRI, but multiplanar visualization o...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200309000-00016
更新日期:2003-09-01 00:00:00
abstract:OBJECTIVE:To assess the accuracy of 64 multidetector-row computed tomography (MDCT) in the diagnosis and staging of gastric cancer. METHODS:This study was approved by the institutional review board, and the patients involved gave informed consent. Forty-four patients (34 men and 10 women; mean age, 57 years) with gast...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/01.rct.0000234072.16209.ab
更新日期:2007-01-01 00:00:00
abstract::Acute infarction of an appendix epiploica resulted in an inflammatory process involving the caudal aspect of the transverse colon and the adjacent greater omentum. Computed tomography demonstrated prominent linear soft tissue densities, an increase in CT number of the involved greater omentum, and posterior displaceme...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198601000-00032
更新日期:1986-01-01 00:00:00
abstract:PURPOSE:To compare the efficacy and patient tolerance of iohexol and meglumine sodium diatrizoate as oral contrast agents for computed tomography (CT). SUBJECTS AND METHODS:One hundred patients were randomly assigned to drink 1000 mL of either meglumine sodium diatrizoate or iohexol 350 before their abdominopelvic CT ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,随机对照试验
doi:10.1097/RCT.0b013e3182058e76
更新日期:2011-03-01 00:00:00
abstract:PURPOSE:We assessed the accuracy of coronary computed tomography angiography (CTA) in patients with an Agatston calcium score (ACS) of greater than 400 by comparing it with invasive coronary angiography (ICA), and we evaluated the predictive value of CTA for obstructive coronary heart disease (CHD) compared with tradit...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e318282d61c
更新日期:2013-05-01 00:00:00
abstract:OBJECTIVE:To describe the computed tomography (CT) and magnetic resonance imaging (MRI) findings of solid organizing hepatic abscesses and correlate them with the pathologic findings. METHODS:Ten patients with 10 pathologically proven solid organizing hepatic abscesses who underwent 3-phase CT (n = 10) or MRI (n = 7) ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200603000-00004
更新日期:2006-03-01 00:00:00
abstract::A simple technique using stereotactic needle placement for retrobulbar anesthesia is reported. The method utilizes a CT-guided stereotactic device that permits precise intraconal injection of local anesthetics; in addition, the risk of injury to muscles, vessels, eyeglobe, or optic nerve is substantially reduced. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199009000-00043
更新日期:1990-09-01 00:00:00
abstract::Three patients are presented in whom computed tomography incidentally demonstrated low density masses posterior to, but separate from, the right kidney. In two, these were proven to represent unilocular cysts, and the third is presumed cystic. Possible etiologies are discussed. ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:
更新日期:1979-12-01 00:00:00
abstract:PURPOSE:Our goal was to examine the effects of collimation width (CW), pitch, viewing plane, and windowing on the display of in-plane vessels in maximum intensity projection (MIP). METHOD:A theoretical concept based on partial volume averaging of vessels was developed to describe the contents of voxels (densities) in ...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-199611000-00018
更新日期:1996-11-01 00:00:00
abstract:OBJECTIVE:To evaluate soft tissue contrast and image quality of a respiratory-triggered echo-planar imaging based diffusion-weighted sequence (EPI-DWI) with different b values for magnetic resonance imaging (MRI) of the liver. METHODS:Forty patients were examined. Quantitative and qualitative evaluation of contrast wa...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0b013e3180dc930c
更新日期:2008-05-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the usefulness of the "bridging vascular sign" in the diagnosis of an exophytic uterine leiomyoma and differentiation of a uterine leiomyoma from some other mass arising in the adnexa on pelvic MRI. METHOD:Of 52 women with a pelvic mass in whom pelvic MRI was performed...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-200001000-00012
更新日期:2000-01-01 00:00:00
abstract::This is the third of a series of 4 white papers that represent Expert Consensus Documents developed by the Society of Computed Body Tomography and Magnetic Resonance through its Task Force on dual-energy computed tomography. This paper, part 3, describes computed tomography angiography and thoracic, cardiac, vascular,...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/RCT.0000000000000538
更新日期:2017-01-01 00:00:00
abstract::A case of isolated spinal cord hemangioblastoma with associated extensive syringohydromyelia, which was evaluated by myelography, postmyelographic CT, magnetic resonance (MR), and angiography is presented. The specific preoperative and postoperative advantages of MR are given as well as a brief review of the literatur...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198805010-00028
更新日期:1988-05-01 00:00:00
abstract::The magnetic resonance characteristics of 16 intracranial arachnoid cysts were evaluated and several features identified that allowed the differentiation from other cystic lesions. Uncomplicated arachnoid cyst contents respond like CSF to both T1 and T2 weighted sequences. Signal from the contiguous brain is of normal...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198703000-00007
更新日期:1987-03-01 00:00:00
abstract::Computed tomography potentially provides an accurate means of determining organ volume, by summation of serial section areas. Variation in level of held respiration for each serial scan, however, severely limits accuracy in the thorax and upper abdomen. A simple strain gauge has been used to provide the patient with v...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198601000-00042
更新日期:1986-01-01 00:00:00
abstract::In view of the lack of ionizing radiation, ability to image in a variety of planes, and high contrast resolution, magnetic resonance (MR) imaging may have a role in obstetrical management. Three fetuses with severe cerebral abnormalities were studied by MR in utero. The findings were correlated with ultrasound examina...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章
doi:10.1097/00004728-198412000-00003
更新日期:1984-12-01 00:00:00
abstract::Pancreas transplantation has become more commonplace over the past several decades. Consequently, the radiological evaluation of patients with such transplants has also become more common. Radiologists must therefore be familiar with the normal imaging appearances of pancreas transplant grafts as well as a wide variet...
journal_title:Journal of computer assisted tomography
pub_type: 杂志文章,评审
doi:10.1097/RCT.0b013e3181966988
更新日期:2009-07-01 00:00:00