[Therapeutic effect of intravaginal application of estriol tablets in the treatment of pathological cervical factor as a cause of sterility].

Abstract:

:81 women were included in a prospective randomised 12-year personal study. The "pathological cervical factor" was confirmed by periovulatory daily examination of the quality of the cervical mucus, using a new modified scheme of cervical score by examining the oestrogenic activity in the vaginal smear and results of sperm-penetration tests after Sims- Huhner , partly also by periovulatory determination of the concentration of luteinising hormone in the serum. The presence of ovulatory cycles could also be determined by regular registration of the cycle length, measurement of the basal body temperature and partly by premenstrual endometrium biopsies; these determinations were of course effected during cycles without therapy. All 81 cases with abnormal preovulatory production of cervical mucus were treated in a total of 234 cycles by intravaginal application of oestriol tablets 1 to maximal 3 mg daily for 1 or more subsequent cycles. On the basis of these criteria, the quality of cervical mucus and postcoital tests improved with a satisfying intravaginal resorption of the oestriol tablets; no side effects were seen. After this therapy, very good results were obtained with intravaginally administered oestriol tablets in 59.3% of the patients with a pregnancy rate of 27.2%; 24.7% of the cases only showed a moderate improvement of the mucus; 16.0% did not respond to oestriol treatment and, therefore, had to be considered as therapeutic failures. The present study again confirms the results of other investigators on the local effectiveness of intravaginal application of oestriol tablets.(ABSTRACT TRUNCATED AT 250 WORDS)

authors

Kofler E

doi

10.1055/s-2008-1036883

subject

Has Abstract

pub_date

1984-04-01 00:00:00

pages

236-42

issue

4

eissn

0016-5751

issn

1438-8804

journal_volume

44

pub_type

临床试验,杂志文章,随机对照试验
  • [Hormonal contraception and substitution therapy: the importance of progestogen for cardiovascular diseases].

    abstract::Epidemiological data have demonstrated, that the progestogen component of oral contraceptives is involved in the development of hypertension, ischaemic heart diseases and stroke. It had been suggested, that atherosclerotic lesions due to the unfavourable effect on lipid metabolism of progestogens with androgenic prope...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2007-1026140

    authors: Kuhl H

    更新日期:1992-11-01 00:00:00

  • [Gynecological and endocrinological studies of thalidomide-damaged girls].

    abstract::Gynaecological examinations were done for the first time in 32 girls, between age 13 and age 18 damaged by thalidomide. 11 of the girls had primary amenorrhoea at the time of examination. 9 of these cases showed genital malformations. 7 cases showed aplasia of the uterus. A rudimentary uterus and a hypo-plastic uterus...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1036884

    authors: Mühlenstedt D,Schwarz M

    更新日期:1984-04-01 00:00:00

  • [Uterine spiral arteries of the human in gestosis, fetal growth retardation and postmaturity].

    abstract::The uterine spiral arteries in humans were examined after a normal course of pregnancy and a pathological course with gestosis, fetal growth retardation and post-term birth. We found that the spiral arterioles in normal pregnancy underwent physiological changes, such as invasion of trophoblasts and decomposition of fi...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035836

    authors: Wang T

    更新日期:1989-06-01 00:00:00

  • [Effectiveness of pre-operative antibiotic prevention in hysterectomies and cesarean section].

    abstract::All controlled studies which were available by computer search from the literature were evaluated regarding the efficiency of preventive antibiotics for post-operative infections following hysterectomies and Cesarian sections. All controlled studies were evaluated by identical criteria. In 41 out of 46 studies (89.1%)...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1036417

    authors: Hirsch HA,Neeser E

    更新日期:1984-01-01 00:00:00

  • [Sickle cell disease and pregnancy].

    abstract::Three million out of 4.5 million foreigners in Germany are from countries, where sickle cell anaemia is found. Today, this disease occurs in Germany with sufficient frequency and this makes it imperative for every physician to be familiar with it. Most of the sickle cell patients today attain the reproductive age. Dur...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1026275

    authors: Dickerhoff R

    更新日期:1990-06-01 00:00:00

  • [Possibilities of ultrasonic examination of the mammae (author's transl)].

    abstract::1,344 women were examined in the course of 3 years by means of the ultrasonic system Multiplanar MS 3 which was coupled direct to the skin. This direct coupling to the skin of the breast and the freely mobile sound head enable immediate puncture of tumours of the breast in direct ultrasonic vision. In multiple cysts i...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1036815

    authors: Mulz D,Althammer G,Knüpfer A

    更新日期:1981-04-01 00:00:00

  • [Acute occlusion of the arterial blood supply of the right arm in a newborn following entanglement of the umbilical cord (author's transl)].

    abstract::Report on the rare event of a complete ischemia of the right arm immediately postpartum. The infant was delivered by Caesarean Section because of cervical dystocia and fetal distress. The umbilical cord was twice around the neck and the ischemia of the right arm appeared to be due to spasm of the axillary artery. Trea...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Muth H,Engelbrecht R

    更新日期:1976-12-01 00:00:00

  • [Clinical experimental studies in the treatment of ovarian dysfunction with bromo-ergocryptin (pravidel) (author's transl)].

    abstract::Among 62 patients with galactorrhoea a corpus luteum deficiency or anovulatory cycles were found in 35 cases by serum progesterone determination, endometrial biopsy or basal body temperature records. 27 patients had a hyperpro-lactenemic amenorrhoea-galactorrhoea syndrome. During treatment with 2.5-5 mg. of Pravidel d...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Diedrich K,Leidenberger F,Lehmann F,Bettendorf G

    更新日期:1978-09-01 00:00:00

  • Sexual Function and Socio-Sexual Difficulties in Women with Polycystic Ovary Syndrome (PCOS).

    abstract::Introduction PCOS is the most common endocrine syndrome in women of the reproductive age that has manifold effects on the life of affected women. Little scientific attention has been devoted to these women's sexual lives. Aim To investigate sexual quality of life in women with PCOS. Methods The sample size was n = 44....

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/a-0828-7901

    authors: Fliegner M,Richter-Appelt H,Krupp K,Brunner F

    更新日期:2019-05-01 00:00:00

  • [Afterloading short-term irradiation of the vagina following radical surgery of uterine cancer].

    abstract::A report is given of results and complications following postoperative irradiation in endometrial carcinoma via monitored high-dose afterloading therapy (iridium 192). Intravaginal irradiation was performed in all operated cases. In advanced cases or in cases with poor prognosis (deep infiltration of the myometrium, t...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035941

    authors: Kucera H,Sagl R,Skodler W,Weghaupt K

    更新日期:1986-10-01 00:00:00

  • [Intra-uterine fetal death following motor vehicle accident (author's transl)].

    abstract::Following an ultra-sound examination in the prenatal clinic as an out-patient the 27 year old gravida: 2 para; 1 sustained severe blunt trauma to the abdomen and a fracture of the pelvis and a cerebral concusion in a motor vehicle accident at 25 weeks gestation. Following admission for the motor vehicle accident the i...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1037340

    authors: Strobel E,Arenz R

    更新日期:1980-05-01 00:00:00

  • [Effect of stress incontinence operations on urodynamic parameters. 1. Is surgical success measurable?].

    abstract::Urodynamic parameters are changed by stress incontinence surgery. Our study, comparing pre- and postoperative measurements in 141 women with urinary stress incontinence, shows an increase of the transmission ratio in the proximal urethra and a decrease of depression factors in the proximal and mid urethra after surger...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1036005

    authors: de Gregorio G,Dietz G,Heisterkamp M,Kaltenbach FJ,Hillemanns HG

    更新日期:1988-06-01 00:00:00

  • [Urodynamic results before and after physiotherapy of women with stress incontinence].

    abstract::With reference to the urodynamic results in 21 women with mild stress incontinence who underwent conservative treatment with pelvic floor exercises over a period of three to six months prior to possible surgery, the author comments on the value of this therapy. At the time of follow-up examination 11 of the women were...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1036370

    authors: Voigt R

    更新日期:1985-08-01 00:00:00

  • [Doppler ultrasound diagnosis in post-term pregnancy].

    abstract::The capability of Doppler flow velocimetry to predict intrauterine growth retardation is well known. The increased morbidity and mortality rate of postterm newborns is also well known. The aim of our study was to examine if Doppler flow velocimetry is able to indicate foetal jeopardy in the postterm period. Flow veloc...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1023595

    authors: Jörn H,Funk A,Fendel H

    更新日期:1993-09-01 00:00:00

  • [Interstitial and intramural pregnancy--definition and sonographic references].

    abstract::Two cases of atypical implantation are presented in order to illustrate the difference between interstitial and intramural pregnancy. Ultrasonography can provide a method of early diagnosis of heterotypic sitting before the occurrence of clinical symptoms. In cases where complications already occurred, sonography can ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026577

    authors: Krone S,Wisser J,Nerlich A,Weissenbacher ER

    更新日期:1989-02-01 00:00:00

  • [Treatment of hypothalamically-induced primary amenorrhea with epimestrol].

    abstract::Eleven patients with hypothalamic primary amenorrhoea, aged between 17 and 23 years, were examined. Each patient was given 10 mg epimestrol (E) orally over a period of 10 days followed by a 20-day pause. This regimen was repeated 6 times. Gonadotropin secretory patterns were investigated between 9 a.m. and 2 p.m. befo...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026661

    authors: Graf M,Specht A,Distler W

    更新日期:1986-07-01 00:00:00

  • [Improving diagnosis of blood supply of breast tumors by echo-contrast media].

    abstract::Doppler blood flow measurements allow differentiation of malignant lesions, that are characterised by an abnormal vascularity. The accuracy of this method is limited due to the physiological flow variation in normal breast parenchyma and in tumours. Magnetic resonance imaging in combination with contrast agents can al...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1023741

    authors: Madjar H,Prömpeler H,Schürmann R,Göppinger A,Breckwoldt M,Pfleiderer A

    更新日期:1993-12-01 00:00:00

  • [The significance of prenatal diagnosis of twins (author's transl)].

    abstract::By means of ultrasound and fetal electrocardiography the diagnosis of twin pregnancies can be made prenatally without any reservation; the diagnosis is even possible in the first half of pregnancy. Comparative analysis of two approximately equal collectives of in all 602 twin pregnancies--1,45% of all births in the ye...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Bolte A,Zippel HH,Berendes R,Meyer V

    更新日期:1978-04-01 00:00:00

  • [Continuous transcutaneous PCO2 measurement and laser spectroscopy for fetal monitoring in 3d degree atrioventricular block].

    abstract::Obstetrical management in case of foetal third-degree AV block has been to date mainly via primary abdominal section, the indication being partly the foetal condition and partly also unsatisfactory childbirth monitoring. The article describes a childbirth associated with AV block, monitoring being effected by continuo...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1026469

    authors: Decleer W,Schmidt S,Gorissen S,Gembruch U,Hansmann M,Krebs D

    更新日期:1990-03-01 00:00:00

  • [Continuous ambulatory intravenous morphine infusion for pain therapy in advanced ovarian cancer].

    abstract::We report on a female outpatient with cancer of the ovary, who received continuous intravenous morphine infusion for terminal pain control. The patient was treated over a period of 48 days with a morphine dosage ranging from 10 to 60 mg/h, which kept her free of pain. With treatment, she was alert, communicative with ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1023754

    authors: Sorge J,Schönborn I,Günter HH,Steffmann B,Hilfrich J,Kühnle H

    更新日期:1992-05-01 00:00:00

  • [Is there a correlation between tubal occlusions in chronic salpingitis and urogenital chlamydia infections?].

    abstract::A prospective study was performed to analyse the relationship between urogenital infections caused by Chlamydia trachomatis and occlusions of the fallopian tubes with histologically confirmed chronic salpingitis and salpingitis isthmica nodosa. 110 infertile patients were tested for C. trachomatis infection. 23 patien...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1022879

    authors: Dieterle S,Mesrogli M,Triebler B,Wollenhaupt J,Nettelnbreker E,Schlösser HW

    更新日期:1994-08-01 00:00:00

  • [Comparison of the results of preoperative studies with imaging procedures with the surgical status of ovarian cancer].

    abstract::Optimal cytoreductive surgery of ovarian cancer is based on the preoperative diagnosis and assessment of tumour spread. Of 147 patients who underwent staging laparotomy at the Department of Gynaecology of the University of Tübingen, intraoperative staging was compared retrospectively with the results of sonography, co...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035841

    authors: Simon WE,Lenz M,Storz A,Straussinsky G,Hirsch HA

    更新日期:1989-06-01 00:00:00

  • Bisphosphonates and their Role in Therapy for Breast Cancer - Results from the PATH Biobank.

    abstract::Introduction: Bisphosphonates are well known above all for their use in the treatment of osteoporosis. They also play an important role as accompanying therapy for advanced tumour diseases with extensive spread into the skeletal system. Their adjuvant use in the treatment of breast cancer without bony metastases is cu...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0032-1328502

    authors: Fick EM,Anzeneder T,Katalinic A,Waldmann A

    更新日期:2013-05-01 00:00:00

  • [The relationship of maternal obesity, excessive weight gain in pregnancy and pre-eclampsia].

    abstract::The records of 2,671 pregnancies were reviewed regarding maternal obesity, excessive weight gain in pregnancy and pre-eclampsia. Pre-eclampsia is significantly more frequent in maternal obesity. Correlation between excessive weight gain in pregnancy and pre-eclampsia is only found for the signs of edema and hypertensi...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Höhn N,Junge S

    更新日期:1979-12-01 00:00:00

  • [Neurofibromatosis and pregnancy].

    abstract::A case of neurofibromatosis (Recklinghausen's disease) in pregnancy in a 29-year-old patient is reported. The woman has had two uncomplicated pregnancies and deliveries. The lesions of the neurofibromatosis did not change during the course of the pregnancy. However, based on the few published cases it is necessary to ...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035910

    authors: Niesert S,Böhme U,Kaulhausen H

    更新日期:1986-04-01 00:00:00

  • Significance of Ovarian Function Suppression in Endocrine Therapy for Breast Cancer in Pre-Menopausal Women.

    abstract::Ovarian function suppression (OFS) for treating breast cancer in pre-menopausal women was introduced for the first time in the late 19th century as bilateral oophorectomy. It was not until the 1960s that the oestrogen receptor was identified and a test for detecting endocrine sensitivity of the breast cancer was devel...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-0042-106389

    authors: Scharl A,Salterberg A

    更新日期:2016-05-01 00:00:00

  • [Pregnancies in HIV infected women in Switzerland].

    abstract::In a national multicentre study, 229 pregnancies in 219 HIV-positive women were prospectively followed up between January 1, 1990, and October 30, 1993. 69.8% were infected by intravenous drug abuse and 91.5% were asymptomatic (CDC classes II and III) in early pregnancy. 48 (21.0%) were first discovered to be HIV-infe...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1022818

    authors: Biedermann K,Rudin C,Irion O,Spoletini G,Lauper U,Kind C

    更新日期:1995-08-01 00:00:00

  • [Pathologic Doppler flow findings and cardiotocography results].

    abstract::Of 1950 pregnant patients (2870 Doppler ultrasound measurements) we observed, in a study group with highly abnormal Doppler-flow findings (n = 66, Feb. 1990), a correlation of Doppler flow and FHR-recordings. Among these 66 patients we retained 60 (91%) in the hospital. They had at least 2 FHR-recordings a day. The re...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2007-1026193

    authors: Schmidt W,Graf von Ballestrem CL,Ertan AK,Rühle W,Gnirs J,Boos R

    更新日期:1991-07-01 00:00:00

  • [Pathology of proximal tubal occlusion--morphologic evaluation. Results following microsurgical anastomosis].

    abstract::Even today, the etiology of proximal tubal occlusion is still a controversial subject. The introduction of microsurgery in gynecology has provided a method of eliminating the main symptom of proximal tubal occlusion, i.e., sterility. Pregnancy rates of 25-30% can be achieved in overall patient collectives. Accurate hi...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035783

    authors: Wiedemann R,Scheidel P,Wiesinger H,Hepp H

    更新日期:1987-02-01 00:00:00

  • Hormone Therapy and its Effect on the Prognosis in Breast Cancer Patients.

    abstract::Introduction: Use of hormone therapy (HT) has declined dramatically in recent years. Some studies have reported that HT use before a diagnosis of breast cancer (BC) may be a prognostic factor in postmenopausal patients. This study aimed to examine the prognostic relevance of HT use before BC diagnosis. Methods: Four B...

    journal_title:Geburtshilfe und Frauenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0035-1546149

    authors: Rauh C,Schuetz F,Rack B,Stickeler E,Klar M,Orlowska-Volk M,Windfuhr-Blum M,Heil J,Rom J,Sohn C,Andergassen U,Jueckstock J,Fehm T,Loehberg CR,Hein A,Schulz-Wendtland R,Hartmann A,Beckmann MW,Janni W,Fasching PA,Häb

    更新日期:2015-06-01 00:00:00