Abstract:
:The fixation of major chromosomal rearrangements with a heterozygote disadvantage is modelled as a simple example of Wright's shifting balance process of evolution in a strongly subdivided population. Chromosomal mutations with an inferior heterozygote become fixed in a local population (or deme) by random genetic drift and spread by migration and colonization. Wright postulated a process of selective diffusion in which the numbers of emigrants and colonizers dispersed from a deme increase with the mean fitness of individuals in it. The present models show that interdeme selection during the spread of a mutation depends more on the capacity of the mutant to invade and become established in other demes than on selective diffusion, unless there is rapid local extinction and colonization. The intensity of interdeme selection is reduced by random local extinction and colonization, and when these processes are rapid (with no selective diffusion) the expected fixation rate of spontaneous mutations with a heterozygote disadvantage approaches that in a single isolated deme. Local extinction and colonization, and selection on the homozygotes, accelerate the spread of chromosomal mutations which are destined to be fixed.
journal_name
Heredity (Edinb)journal_title
Heredityauthors
Lande Rdoi
10.1038/hdy.1985.43subject
Has Abstractpub_date
1985-06-01 00:00:00pages
323-32eissn
0018-067Xissn
1365-2540journal_volume
54 ( Pt 3)pub_type
杂志文章相关文献
HEREDITY文献大全abstract::A variety of questions in population and evolutionary biology are studied using chloroplast DNA (cpDNA). The presumed maternal inheritance in angiosperms allows for certain assumptions and calculations to be made when studying plant hybridization, phylogeography, molecular systematics and seed dispersal. Further, the ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2008.11
更新日期:2008-06-01 00:00:00
abstract::Many Odonata species exhibit female-limited polymorphisms, where one morph is similar to the conspecific male in body color and other traits (andromorph), whereas one or more other morphs differ from the male (gynomorphs). Here we investigated the differentially expressed transcripts (DETs) among males and two female ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-018-0076-z
更新日期:2019-01-01 00:00:00
abstract::Crop modelling has so far contributed little to the genetic analysis of a quantitative trait. This study illustrates how a simple model for crop phenological development, which assumes that crop development rate is affected by daily effective temperature, can assist the identification of Quantitative Trait Loci (QTLs)...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6885030
更新日期:1999-04-01 00:00:00
abstract::Host-plant resistance is an effective method for controlling soybean aphid (Aphis glycines Matsumura), the most damaging insect pest of soybean (Glycine max (L.) Merr.) in North America. Recently, resistant soybean lines have been discovered and at least four aphid resistance genes (Rag1, Rag2, Rag3 and rag4) have bee...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2013.10
更新日期:2013-07-01 00:00:00
abstract::Insect cuticle melanism is linked to a number of life-history traits, and a positive relationship is hypothesized between melanism and the strength of immune defense. In this study, the phenotypic and genetic relationships between cuticular melanization, innate immune defense, individual development time and body size...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2013.20
更新日期:2013-08-01 00:00:00
abstract::Small populations of our study species Ranunculus reptans have reduced fitness because of inbreeding, genetic load, and reduced mate availability; that is, they suffer from a three-fold genetic Allee effect. Here, we investigate how the effect of interpopulation outbreeding on offspring fitness depends on population s...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800732
更新日期:2005-12-01 00:00:00
abstract::Relatedness between individuals is central to ecological genetics. Multiple methods are available to quantify relatedness from molecular data, including method-of-moment and maximum-likelihood estimators. We describe a maximum-likelihood estimator for autopolyploids, and quantify its statistical performance under a ra...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/hdy.2014.88
更新日期:2015-02-01 00:00:00
abstract::Recent molecular genetic analyses of Drosophila melanogaster and mouse central nervous system (CNS) development revealed strikingly similar genetic patterning mechanisms in the formation of the insect and vertebrate brain. Thus, in both insects and vertebrates, the correct regionalization and neuronal identity of the ...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/sj.hdy.6800664
更新日期:2005-05-01 00:00:00
abstract::Dispersal in most plants is mediated by the movement of seeds and pollen, which move genes across the landscape differently. Grevillea macleayana is a rare, fire-dependent Australian shrub with large seeds lacking adaptations for dispersal; yet it produces inflorescences adapted to pollination by highly mobile vertebr...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800308
更新日期:2003-11-01 00:00:00
abstract::Araucaria araucana (Monkey Puzzle), a southern South American tree species of exceptional cultural and economic importance, is of conservation concern owing to extensive historical clearance and current human pressures. Random amplified polymorphic DNA (RAPD) markers were used to characterise genetic heterogeneity wit...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800033
更新日期:2002-04-01 00:00:00
abstract::Habitat fragmentation is a major cause of biodiversity loss, responsible for an alteration of intraspecific patterns of neutral genetic diversity and structure. Although neutral genetic variation can be informative for demographic inferences, it may be a poor predictor of adaptive genetic diversity and thus of the con...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-020-00366-w
更新日期:2021-01-01 00:00:00
abstract::MtDNA restriction fragment polymorphisms were found between cytoplasmic male-sterility types P and R of Plantago lanceolata with the homologous probe pPl311 and maize mtDNA fragments derived from the regions of atp1, cox1 and cox2. No mtDNA differences were observed between male- sterile and restored plants with the s...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6880780
更新日期:1997-01-01 00:00:00
abstract::Quantifying the effect of pollen dispersal and flowering traits on mating success is essential for understanding evolutionary responses to changing environments and establishing strategies for forest tree breeding. This study examined, quantitatively, the effects of male fecundity, interindividual distance and anisotr...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2011.76
更新日期:2012-03-01 00:00:00
abstract::Gene flow via pollen movement affects genetic variation in plant populations and is an important consideration in plant domestication. Fontainea picrosperma is a subcanopy rainforest tree that is of commercial interest because it is the source of tigilanol tiglate, a natural product used for the treatment of solid tum...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/s41437-019-0231-1
更新日期:2019-10-01 00:00:00
abstract::Population genetic signatures of local adaptation are frequently investigated by identifying loci with allele frequencies that exhibit high correlation with ecological variables. One difficulty with this approach is that ecological associations might be confounded by geographic variation at selectively neutral loci. H...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.7
更新日期:2015-07-01 00:00:00
abstract::We examine seven geographically separate subpopulations of Heliconius charithonia, a butterfly with well-documented home range behaviour, in Miami-Dade County, Florida, for genetic differentiation using cellulose acetate electrophoresis. These subpopulations exhibit little genetic variation (percent polymorphic loci =...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00830.x
更新日期:2001-02-01 00:00:00
abstract::We examined the amount and nature of variation revealed by cDNA-based sequence-tagged-site (STS) markers in Norway spruce (Picea abies (L.) Karst.) using 39 pairs of heterologous primers that were based upon arbitrary genes in black spruce (Picea mariana (Mill.) B.S.P.). A panel of 22 diverse Norway spruce genotypes w...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6885740
更新日期:1999-09-01 00:00:00
abstract::Many lepidopteran insects exhibit body colour variations, where the high phenotypic diversity observed in the wings and bodies of adults provides opportunities for studying adaptive morphological evolution. In the silkworm Bombyx mori, two genes responsible for moth colour mutation, Bm and Ws, have been mapped to 0.0 ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.69
更新日期:2016-01-01 00:00:00
abstract::We have constructed a linkage map for the peppered moth (Biston betularia), the classical ecological genetics model of industrial melanism, aimed both at localizing the network of loci controlling melanism and making inferences about chromosome dynamics. The linkage map, which is based primarily on amplified fragment ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2012.84
更新日期:2013-03-01 00:00:00
abstract::Haploid nuclear DNA of 23 species of Aedes, as determined by Feulgen cytophotometry, was found to vary 3-fold. This was accompanied by a 2-fold variation in total chromosomal length. There was a significant correlation (r = 0.765, P less than 0.001) between these two parameters. Genome size varied from 0.87 pg to 1.3 ...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.1987.120
更新日期:1987-10-01 00:00:00
abstract::Plants are sessile organisms, often characterized by limited dispersal. Seeds and pollen are the critical stages for gene flow. Here we investigate spatial genetic structure, gene dispersal and the relative contribution of pollen vs seed in the movement of genes in a stable metapopulation of the white campion Silene l...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2010.38
更新日期:2011-01-01 00:00:00
abstract::The hypothesis that traits closely associated with fitness will generally possess lower heritabilities than traits more loosely connected with fitness is tested using 1120 narrow sense heritability estimates for wild, outbred animal populations, collected from the published record. Our results indicate that life histo...
journal_title:Heredity
pub_type: 杂志文章,评审
doi:10.1038/hdy.1987.113
更新日期:1987-10-01 00:00:00
abstract::Geographical patterns of gene flow and drift were analysed in the commensal cellar spider Pholcus phalangioides to get insight into the causes affecting genetic variation in this species strictly associated with man. Our sampling consisted of 23 subpopulations collected over five urban regions in central Europe (dista...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00815.x
更新日期:2001-01-01 00:00:00
abstract::Variations observed in parasite virulence and host resistance may be the outcome of coevolutionary processes. Recent theoretical developments have led to a 'geographic mosaic theory' of coevolution according to which there are some localities where reciprocal selection occurs (hot spots) and others where it is strongl...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800182
更新日期:2003-01-01 00:00:00
abstract::Nothofagus cunninghamii is a long-lived, wind-pollinated tree species that dominates the cool temperate rainforests of southeastern Australia. The species' distribution is more or less continuous in western Tasmania but is fragmented elsewhere. However, it is unknown whether this fragmentation has affected the species...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.77
更新日期:2016-01-01 00:00:00
abstract::Allele frequency differences between sexes and an excess of heterozygotes in males had suggested that the PEPB-1 locus is sex-linked in chinook salmon (Oncorhynchus tshawytscha). We here estimate less than 1% recombination between PEPB-1 and a growth hormone pseudogene known to be in the sex-determining region (SEX) i...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800483
更新日期:2004-07-01 00:00:00
abstract::Environmental stress generally exacerbates the harmful effects of inbreeding and it has been proposed that this could be exploited in purging deleterious alleles from threatened inbred populations. However, understanding what factors contribute to variability in the strength of inbreeding depression (ID) observed acro...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2015.103
更新日期:2016-03-01 00:00:00
abstract::Fluctuating asymmetry (FA) has been proposed as a tool to measure levels of stress experienced by populations of organisms during development. To be of value as a bio-marker to highlight conditions at particular sites, it is important that variation in FA is due to environmental (eg pollution) variation and not geneti...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/sj.hdy.6800045
更新日期:2002-04-01 00:00:00
abstract::Knowledge of the degree of temporal stability of population genetic structure and composition is important for understanding microevolutionary processes and addressing issues of human impact of natural populations. We know little about how representative single samples in time are to reflect population genetic constit...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1038/hdy.2012.36
更新日期:2012-10-01 00:00:00
abstract::Random amplified polymorphic DNA (RAPD) analysis was performed to characterize the genetic diversity of Austropotamobius pallipes, a threatened freshwater crayfish native to Europe. Four decamer primers which generated six unambiguous polymorphic bands were used to analyse crayfish from 21 populations sampled in the m...
journal_title:Heredity
pub_type: 杂志文章
doi:10.1046/j.1365-2540.2001.00909.x
更新日期:2001-07-01 00:00:00