Abstract：
:Absorption of theophylline from one commercial product labelled as aminophylline sustained release was compared to the absorption from an oral solution of aminophylline in a single-dose bioavailability study. Aminomal-R tablets had bioavailability (101.2 +/- 19) statistically indistinguishable from that of the standard but showed significantly slower absorption (peak times of 3.6 +/- 1.1 h vs 1.3 +/- 0.8 h) and lower peak plasma concentrations (16.8 +/- 4.7 mg/l/1 g aminoph. dose vs 21.1 +/- 4.2 mg/l/1 g aminoph. dose). Projections of plasma concentrations upon multiple dosing were made from single dose data: the dosage interval (every 12 h) concentration ratio which reflects both the frequency of dosing and the entry of the drug into and removal from the body was of 1.8 vs 3.1.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Regazzi MB,Guarnone E,Bartoli A,Ciardelli L,Piacentini Psubject
Has Abstractpub_date
1985-03-31 00:00:00pages
641-5issue
13eissn
0026-4806issn
1827-1669journal_volume
76pub_type
杂志文章相关文献
MINERVA MEDICA文献大全abstract：:After a brief examination of the recent literature on non-secretory multiple myeloma, the Authors describe the immunohistologic study (peroxidase-antiperoxidase method) of a case of truly non producing plasmacytoma, interesting because of the presence of a small polyclonal plasma cell population within the neoplastic ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-06-30 00:00:00
abstract：:It is well known that deep hypothermia used in open-heart surgery is usually associated with a marked reduction in carbohydrate tolerance, especially dangerous in the diabetic patient, since it might result in severe metabolic complications, namely ketosis and hyperosmolar coma. In order to prevent the occurrence of s...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-12-22 00:00:00
abstract：:A group of heart patients and another group of healthy subjects have been studied and their systolic intervals (PEP-LVET - PEP/LVET ratio and the telediastolic index) evaluated using the mechanocardiographic system. In both long-standing and recent heart patients, the parameters studied showed significant deviations f...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-09-15 00:00:00
abstract：:A comparison between echographic and bioptic findings in diffuse liver disease is reported. The data obtained are compared with those quoted in the literature and found to be very similar. Finally echography is identified as the indispensable examination of choice. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-05-12 00:00:00
abstract：:The authors, after a review of the literature about TNS, suggest the comparison between three different TNS techniques from two points of view: A) Pain relief estimate; B) Response to Naloxone Test. To this purpose a impulse generator delivered a biphasic square-wave stimulus with duration of 0.40 msec and amplitude (...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-04-21 00:00:00
abstract：BACKGROUND:The synthetic mucolytic neltene-xine is an amide derivative of ambroxol and thiophencarboxylic acid. The aim of this open, randomised, controlled study versus sobrerol was to evaluate the efficacy and tolerability of neltenexine (oral granules in sachets) as compared with sobrerol (oral granules in sachets),...
journal_title：Minerva medica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-08-01 00:00:00
abstract：:Anatomopathological, clinical, therapeutical aspects of intraluminal duodenal diverticulum are analyzed. This is an illness of which are described in all literature of world about 47 to 70 cases. On intraluminal duodenal diverticulum is described with x rays examinations. The diagnosis of this illness is made by radio...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1980-06-30 00:00:00
abstract：:The value of serum ferritin assays in the diagnosis and staging of non-microcytoma bronchial cancer is assessed. It is pointed out that the marker is only minimally specific and sensitive in the diagnostic phase as well as being only slightly indicative in the staging of NSCLC. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-12-15 00:00:00
abstract：:Results obtained with immunotherapy in 318 cases of lung cancer showed that an initial Tine test is useful prognostically (initial negativity is equivalent to poor survival), and survival increases and decreases in function of positivity and negativity respectively. The soundness of immunotherapy is borne out by the s...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-12-29 00:00:00
abstract：:A case of acquired idiopathic agammaglobulinaemia in a 23-yr-old woman is presented. The picture included frequent and recurrent lung, sinus and mastoid infections, and diarrhoea. The pathogenesis, radiological picture, and differential diagnosis of this immunological disorder are described. ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1980-04-02 00:00:00
abstract：AIM:The aim of this analysis was to investigate the clinical characteristics and prognosis of patients with serum alpha-fetoproteinpositive gastric cancer (AFPGC) in order to improve the diagnosis and treatment. METHODS:A retrospective analysis was performed on the clinical characteristics and survival data of patient...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：2015-08-01 00:00:00
abstract：:Although mammary pain is the most common reason prompting women to seek breast examination, it is considered to unimportant to be fully investigated and often treatment is extremely superficial. A projected investigation of the natural history of mammary pain through examination of the symptomatology of the commonest ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1985-01-28 00:00:00
abstract：:An account is given of some peculiar ECG pictures observed during two studies performed at the Air Force Aerospatial Medicine Research Centre. The first study covered in-flight heart rate recordings in trainee pilots and can be regarded as an early example of dynamic ECG, as also employed in the rehabilitation of hear...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1979-10-27 00:00:00
abstract：:A retrospective study of 561 patients with silicosis and 234 with asbestosis was performed to assess whether lung function decline in five years is related to the type (restrictive or obstructive) and/or to the degree of initial damage. Based on lung function tests, three groups of patients were identified: NC with no...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1987-12-31 00:00:00
abstract：:Changes in haematocrit values were determined in chronic bronchitis patients undergoing water depletion with diuretics. Unchanged, increased and decreased values were observed. The results were statistically significant and indicated that: 1) increases correspond to a decrease in the amount of extracellular water; 2) ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1974-12-22 00:00:00
abstract：:The present paper deals with an ischaemic syndrome which may affect an area of lower limb vessels with latent arteriopathy if limbs or whole body are immersed in very warm water. Two cases are described in which ischaemia appeared when the limbs involved were immersed in warm water (38 degrees C). Ischaemia may be exp...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-10-27 00:00:00
abstract：:The first part of the paper examines the reasons for involving the patient's family in suggestion and autogenous therapy, giving details of the advantages and limitations of this involvement and listing the pathologies in which it is employed. Finally, the use of autogenous techniques as an aid in the diagnosis of the...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1990-03-01 00:00:00
abstract：AIM:To investigate the hippocampal regional deformation modes by means of a novel method of automatic segmentation for discriminating between Alzheimer's disease (AD) and normal aging; and to further provide the effective evidence for the early diagnosis of AD. METHODS:Twenty AD patients and sixty healthy volunteers w...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：2014-04-01 00:00:00
abstract：:Loss of his social role and various other stresses result in a psychological feeling of impotence and nothingness in the aged. Physicians should make a close study of these aspects and not identify the aged with the end of finality and segregation. Adaptation to old age is determined by the years preceding it and doct...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1978-05-26 00:00:00
abstract：:The diagnostic possibilities of Doppler velocimetry with spectral analysis have been assessed in the diagnosis of benign and malignant breast cancers. The study considers 18 patients with mammary nodules. The data obtained with Doppler velocimetry are compared with those of mammographic, cytological and histopathologi...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1989-05-01 00:00:00
abstract：:The intravenous arteriography, both in traditional radiology or tomography and in computed tomography (angio-TC) requires the administration of large quantities of contrast medium and the application of intense doses of radiation to a patient. The method of Schad is based on a suitable technique of injection and on th...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1984-07-14 00:00:00
abstract：:Urinary infections often complicate the clinical course of hospitalised patients especially those with immunological diseases or under antibiotic treatment for other infectious pathologies. Urethral catheterisation is also a well known cause of such infections. The problem of urinary infections was examined in a gener...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1986-07-14 00:00:00
abstract：:The ability of basophils and tissue mastocytes activated by sensitised IgE antibodies to release mediators in the presence of the specific antigen underlies immediate hypersensitivity reactions. This phenomenon can be explored by the in vitro basophil degranulation test adopted not only in experimental pathology, but ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1981-06-30 00:00:00
abstract：: ...
journal_title：Minerva medica
pub_type： 信件
doi：10.23736/S0026-4806.19.05976-7
更新日期：2019-10-01 00:00:00
abstract：AIM:Management of functional dyspepsia is still controversial. Different controlled trials reported a superiority of prokinetics, H2-receptor antagonists and proton-pump inhibitors over placebo; nevertheless, symptomatic improvement after therapy is often incomplete and some of these drugs possess serious side effects....
journal_title：Minerva medica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2011-04-01 00:00:00
abstract：:The prevalence of cholelithiasis was determined by ultrasound in 168 patients affected by chronic liver disease and compared to 828 subjects of the general population. We found an increase of cholelithiasis in chronic liver patients (p less than 0.004). This difference persisted separating the subjects in males (p les...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1991-11-01 00:00:00
abstract：:In evaluating pre- and post-operative immunological status of 15 patients with malignant breast and thyroid tumors and of 9 patients with benign breast and thyroid lesions, rosette E test, CEA, cortisol, immunocomplexes and determination of circulating leukocytes, B lymphocytes and immunoglobulins was employed. The ob...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1982-04-28 00:00:00
abstract：:Multivaried and trend analyses were applied to a set of 27 periodic haematochemical checks on 37 patients given surgery for biliopancreatic pathology. Preoperative and postoperative data were separately analysed. The software employed was specially designed for the purpose. The discriminating function was used in the ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1983-02-25 00:00:00
abstract：:18 cases of anatomically verified lung cancer were studied scintigraphically with microspheres of human albumin labelled with 99Tc, mercury bichloride (197Hg) and citrate of gallium (67Ga), to assess the diagnostic value of this technique. Using albumin microspheres, changes in the scintigraphic picture were obtained ...
journal_title：Minerva medica
pub_type： 杂志文章
doi：
更新日期：1976-10-27 00:00:00
abstract：:The considerable progress made recently in the study of amyloid substance have led to the identification of numerous organised protein components in typical microfibrillar structures. In spite of the biochemical heterogeneity of fibril proteins, it is still possible to find similar chemicophysical and tintorial featur...
journal_title：Minerva medica
pub_type： 杂志文章,评审
doi：
更新日期：1980-06-23 00:00:00
