Abstract:
:Crystals of an almost self-complementary DNA 15-mer d(CGCGAAATTTACGCG) have been grown by the vapor diffusion technique at 4 degrees C. The space group is I222 with a = 37.3 A, b = 54.6 A and c = 104.8 A. Solution studies showed that the 15-mer forms a duplex with the extra adenine residue unpaired: (sequence; see text) Crystals are stable at 4 degrees C and are suitable for medium-resolution structural studies.
journal_name
J Mol Bioljournal_title
Journal of molecular biologyauthors
Miller M,Wlodawer A,Appella E,Sussman JLdoi
10.1016/0022-2836(87)90503-1subject
Has Abstractpub_date
1987-06-20 00:00:00pages
967-8issue
4eissn
0022-2836issn
1089-8638pii
0022-2836(87)90503-1journal_volume
195pub_type
杂志文章abstract::Analysis of the conformational differences between the oxy and deoxy forms of hemoglobin is complicated by shifting coordinate systems and correlated motions between different parts of the molecule. Methods independent of any frame of reference were used to study the differences in structure between the oxy and deoxy ...
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