Abstract：
OBJECTIVES:Chlorhexidine (CHX) is a commonly used antiseptic mouthwash, used by dental practitioners and the public, due to its antimicrobial effects. The aim of this article was to provide a narrative review of current antimicrobial uses of CHX relevant to dentistry in the context of oral diseases, highlighting need for further studies to support its safe and appropriate use. STUDY SELECTION, DATA AND SOURCES:Randomised controlled trials, systematic reviews and national (UK and US) guidelines were consulted where available, with search terms for each subject category entered into MEDLINE, PubMed, Google Scholar and the Cochrane database. RESULTS:Some evidence existed to support adjunctive short-term use of CHX to manage dental plaque, and reduce clinical symptoms of gingivitis, dry socket, as well as reduce aerosolisation of bacteria. However, use must be weighed alongside the less desirable effects of CHX, including extrinsic staining of teeth, antimicrobial resistance to antiseptic agents and the rare, but fatal, allergic reactions to CHX. Conversely, evidence for the effectiveness of chlorhexidine to manage or prevent periodontitis, dental caries, necrotising periodontal diseases, peri-implantitis, and infections associated with extraction and aerosolised viruses remains less certain. CONCLUSIONS:The use of CHX in dentistry and oral healthcare continues to be widespread and thus it is important that dental practitioners understand that, based on its differential mechanisms of action on different microbes, appropriate clinical and dental use of CHX should be oral disease specific. However, further scientific and clinical research is required before full recommendations can be made.
journal_name
J Dentjournal_title
Journal of dentistryauthors
Brookes ZLS,Bescos R,Belfield LA,Ali K,Roberts Adoi
10.1016/j.jdent.2020.103497subject
Has Abstractpub_date
2020-12-01 00:00:00pages
103497eissn
0300-5712issn
1879-176Xpii
S0300-5712(20)30244-Xjournal_volume
103pub_type
杂志文章,评审abstract：OBJECTIVES:To integrate items from two widely used oral health-related quality of life (OHRQoL) questionnaires, the General Oral Health Assessment Index (GOHAI) and the Oral Impacts on Daily Performances (OIDP), as well as culturally-specific items of the Oral Health Impact Profile (OHIP) into a four-dimensional OHRQoL...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2016.06.006
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVES:To explore the association between frequency of consumption of sugar-sweetened beverages (SSB) and caries increment over 4 years in adults. A second objective was to explore whether the association between frequency of SSB consumption and caries increment varied by socio-demographic characteristics and use o...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2014.04.011
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVES:A meta-analysis was conducted to assess the relationship between parental age and the occurrence of non-syndromic oral clefts. The questions addressed if younger or older mothers and fathers have an increased risk of having a child with non-syndromic oral clefts. DATA:Data from cohort studies, case-control,...
journal_title：Journal of dentistry
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jdent.2011.10.002
更新日期：2012-01-01 00:00:00
abstract：OBJECTIVES:This study aimed to evaluate the effect of low-fluoride toothpastes with calcium glycerophosphate (CaGP) on enamel remineralization in situ. METHODS:Volunteers (n=10) wore palatal devices holding four bovine enamel blocks. The treatments involved 5 experimental phases of 3 days each according to the followi...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2014.09.001
更新日期：2014-12-01 00:00:00
abstract：AIM:It is the aim of this paper to investigate the survival of direct-placement restorations provided within the General Dental Services in England and Wales, in relation to the dentist factors which may affect this. METHODS:For this work, survival of a restoration was considered to be the time between the date of com...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.03.009
更新日期：2005-11-01 00:00:00
abstract：:Maximum lateral forces as measured by strain gauges mounted on the analysing rod of a Nesor surveyor for four operators during surveying procedures ranged from 81 to 110 cN (mean 92.4 cN). Maximum lateral forces used when trimming blockout and inlay wax ranged from 159 to 184 cN (mean 169 cN) and 137 to 196 cN (mean 1...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/0300-5712(91)90012-n
更新日期：1991-06-01 00:00:00
abstract：OBJECTIVES:Verify the influence of curing methods on contraction stress, stress rate, and degree of conversion (DC) of a restorative composite and on bond strength of composite restoratives. METHODS:For the stress test, composite (0.84 mm thick) was applied between two 5-mm diameter glass rods, mounted in a servohydra...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2006.10.003
更新日期：2007-04-01 00:00:00
abstract：OBJECTIVES:To investigate differentially expressed salivary peptides in the development of early childhood caries (ECC) in 3-4 year-old children. MATERIALS AND METHODS:Eighty-two caries-free children at baseline were followed-up for 1year, during which period 15 of them had developed ECC (Group C), whilst another 15 c...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2017.04.006
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVES:Three activated organofunctional silane coupling agents alone and blended with a non-functional cross-linker silane were evaluated as adhesion promoters in an experiment where a bis-GMA (bis-phenol-A-diglycidyldimethacrylate) resin was bonded to silicatized titanium. The adhesive performances of the silanes ...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2006.01.008
更新日期：2006-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the induced changes in the chemical and mechanical performance at the glass-ionomer cement-dentin interface after mechanical load application. METHODS:A conventional glass-ionomer cement (GIC) (Ketac Bond), and a resin-modified glass-ionomer cement (RMGIC) (Vitrebond Plu...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2018.04.006
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVES:Ultrasound may offer a possible alternative to rotary instruments for removing bone. This study was undertaken to analyse in vitro the various factors that influence the cutting of bone by an ultrasonic chisel. STUDY DESIGN:A block of bovine femur was moved in a longitudinal direction under a stationary ult...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(99)00044-5
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:To monitor zirconia-ceramic and metal-ceramic posterior FDPs with respect to survival and technical/biological complication rates. MATERIALS AND METHODS:Fifty-eight patients received 76 3- to 5-unit posterior FDPs. The sites were randomly assigned to 40 zirconia-based (ZC) and 36 metal-based (MC) FDPs. FDPs...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2018.05.015
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVES:Previously, we have reported that dental composite incorporating the new monomer methacryloyloxydodecylpyridinium bromide (MDB) showed no release of antibacterial components after being cured but still exhibited antibacterial activity against Streptococcus mutants on its surface. In this study, in order to e...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/0300-5712(95)93576-n
更新日期：1995-06-01 00:00:00
abstract：OBJECTIVE:Bitewing radiographs are the main tool for approximal caries detection. However, interpretation of findings is affected by numerous factors, such as beam angulation, exposure conditions, morphologic variations, etc. The objective of the present study was to compare the ability to detect virtually identical, a...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/0300-5712(95)00111-5
更新日期：1996-11-01 00:00:00
abstract：OBJECTIVES:The aim of this in vitro study was to evaluate the penetration of an infiltrant and a sealant, when applied as recommended, into fissure caries lesions. METHODS:The fissure systems of extracted human teeth were classified according to the international caries detection and assessment system (ICDAS, codes: 0...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2014.01.006
更新日期：2014-04-01 00:00:00
abstract：OBJECTIVE:The fracture of bonded ceramic to metal restorations remains a problem in clinical dental practice. The use of resin based composites to repair such fractures is generally unsatisfactory. Tribochemical technology creates a surface layer of small silica particles fused to the surface substrate. Such a layer po...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/s0300-5712(00)00006-3
更新日期：2000-08-01 00:00:00
abstract：OBJECTIVES:Evaluate color and translucency of both non-colored and colored zirconia ceramics and compare them with corresponding properties of human dentine. METHODS:0.5mm thick samples of human (MSHD) and bovine (MSBD) dentine were obtained from 5 extracted human anterior maxillary teeth and 5 bovine incisors, respec...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.08.018
更新日期：2012-12-01 00:00:00
abstract：OBJECTIVES:Mutans streptococci and Lactobacilli on impressions of teeth and caries tests were used to identify caries prone subjects. METHODS:Twenty-seven dental students were examined for caries initially and after 4 years. At the initial examination plaque index; saliva flow, buffering capacity and lysozyme; sucrose...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2008.07.004
更新日期：2008-11-01 00:00:00
abstract：:The Annual Conference of the British Association of Teachers of Conservative Dentistry (BATCD) was held in Sheffield on 16 and 17 September 1993. The main programme addressed educational issues in three areas: the undergraduate/vocational-trainee interface, the teaching of implants in the undergraduate curriculum, and...
journal_title：Journal of dentistry
pub_type：
doi：10.1016/0300-5712(94)90069-8
更新日期：1994-10-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to investigate the effect of silver diamine fluoride (SDF) therapy on the oral health-related quality of life (OHRQoL) of preschool children and their families in a school-based setting. METHODS:A prospective study was conducted in six kindergartens in Hong Kong. Parents of the chil...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2018.12.004
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:The study evaluated the clinical performance and marginal adaptation of direct and semi-direct class II composite restorations in a split-mouth design over 3.5 years. DESIGN:44 upper posterior teeth in 11 adults with primary carious lesions were treated with 22 direct and 22 semi-direct restorations. Convent...
journal_title：Journal of dentistry
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.jdent.2004.11.009
更新日期：2005-07-01 00:00:00
abstract：OBJECTIVES:To evaluate the changes in oral health-related quality of life (OHRQoL) reported by subjects treated with conventional prostheses. METHODS:A consecutive sample of 153 patients seeking prosthodontic rehabilitation was recruited. Socio-demographic and prosthetic-related factors (Eichner Index; number of occlu...
journal_title：Journal of dentistry
pub_type： 临床试验,杂志文章
doi：10.1016/j.jdent.2013.01.006
更新日期：2013-06-01 00:00:00
abstract：UNLABELLED:Soy beverages are water extracts of whole soybeans and are often promoted as a healthy alternative to bovine milk. Little analysis has been carried out to determine the effects of soy beverages on oral health, especially their potential acidogenicity. OBJECTIVES:The aim of this study was to determine the po...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.05.004
更新日期：2012-09-01 00:00:00
abstract：INTRODUCTION:We assessed time trends in root caries experience, i.e. the sum of filled and carious root surfaces (FRS, CRS), and evaluated risk indicators of FRS/CRS in Germany. METHODS:FRS and CRS from repeated waves (1997, 2005, 2014) of the nationally-representative German Oral Health Studies were analyzed in 35-44...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2018.08.013
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVES:Methacrylic compounds such as 2-hydroxyethyl methacrylate (HEMA), triethylene glycol dimethacrylate (TEGDMA) and bisphenol A glycerolate (1 glycerol/phenol) dimethacrylate (Bis-GMA) are largely present in auto- or photopolymerizable composite resins. Since the polymerization reaction is never complete, these...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2006.07.008
更新日期：2007-03-01 00:00:00
abstract：OBJECTIVES:This longitudinal randomized controlled clinical trial evaluated the longevity of composite resin inlays in single- or multi-surface cavities up to 4 years. METHODS:21 dental students placed 75 Artglass and 80 Charisma composite resin inlays in class I and II cavities in posterior teeth (89 adult patients) ...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2011.04.005
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:An accurate evaluation of the extent of dental caries and possible progress of the lesion from enamel into dentin is very important in clinical dentistry. Dentists need an imaging technology that can noninvasively and reliably quantify the extent of caries. This study aimed to evaluate the effectiveness of no...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.10.007
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to examine the behavior of posterior teeth restored with single-tooth restorations with intentionally high occlusal contacts. METHODS:Consent was obtained from 17 patients who were seen a total of 5 times over 3.5 years. The restorations placed were all full occlusal coverage gold r...
journal_title：Journal of dentistry
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jdent.2015.11.006
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVES:To determine the correlation between fracture toughness and leucite content in dental porcelains. The mechanisms by which leucite influences the fracture toughness of dental porcelains were also investigated. METHODS:Six porcelains were tested: A (Ceramco I/Dentsply), B (Ceramco II/Dentsitply), C (Finesse/D...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2005.02.001
更新日期：2005-10-01 00:00:00
abstract：OBJECTIVES:To assess the cuspal deflection and cervical microleakage of standardised Class II cavities incrementally filled with a dimethacrylate RBC or bulk-fill flowable RBC bases. METHODS:Twenty-four sound upper premolar teeth with Class II cavities were allocated to three groups (n=8). Restoration of the teeth inv...
journal_title：Journal of dentistry
pub_type： 杂志文章
doi：10.1016/j.jdent.2012.02.015
更新日期：2012-06-01 00:00:00
