Abstract:
BACKGROUND:Impaired in utero fetal growth trajectory may have long term health consequences of the newborns and increase risk of adulthood metabolic diseases. Prenatal exposure to air pollution has been linked to fetal development restriction; however, the impact of exposure to ambient air pollutants on the entire course of intrauterine fetal development has not been comprehensively investigated. METHODS:During 2015-2018, two cohorts of mother-infant dyads (N = 678 and 227) were recruited in Shanghai China, from which three categories of data were systematically collected: (1) daily exposure to six air pollutants during pregnancy, (2) fetal biometry in the 2nd (gestational week 24, [GW24]) and 3rd trimester (GW36), and (3) neonatal outcomes at birth. We investigated the impact of prenatal exposure to air pollutant mixture on the trajectory of fetal development during the course of gestation, adjusting for a broad set of potential confounds. RESULTS:Prenatal exposure to PM2.5, PM10, SO2 and O3 significantly reduced fetal biometry at GW24, where SO2 had the most potent effect. For every 10 μg/m3 increment increase of daily SO2 exposure during the 1st trimester shortened femur length by 2.20 mm (p = 6.7E-21) translating to 5.3% reduction from the average of the study cohort. Prenatal air pollution exposure also decreased fetal biometry at GW36 with attenuated effect size. Comparing to the lowest exposed quartile, fetus in the highest exposed quartile had 6.3% (p = 3.5E-5) and 2.1% (p = 2.4E-3) lower estimated intrauterine weight in GW24 and GW36, respectively; however, no difference in birth weight was observed, indicating a rapid catch-up growth in the 3rd trimester. CONCLUSIONS:To our knowledge, for the first time, we demonstrated the impact of prenatal exposure to ambient air pollutants on the course of intrauterine fetal development. The altered growth trajectory and rapid catch-up growth in associated with high prenatal exposure may lead to long-term predisposition for adulthood metabolic disorders.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Shao X,Cheng H,Zhou J,Zhang J,Zhu Y,Yang C,Di Narzo A,Yu J,Shen Y,Li Y,Xu S,Zhang Z,Chen J,Cheng J,Hao Kdoi
10.1016/j.ecoenv.2020.110726subject
Has Abstractpub_date
2020-09-15 00:00:00pages
110726eissn
0147-6513issn
1090-2414pii
S0147-6513(20)30565-0journal_volume
201pub_type
杂志文章abstract::Cistus monspeliensis L. is a species that grows spontaneously in contaminated mining areas of the Iberian Pyrite Belt. This species can accumulate high concentrations of As in the shoots without visible signs of phytotoxicity. In order to understand the physiological mechanisms underlying this tolerance, C. monspelien...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.12.098
更新日期:2019-04-30 00:00:00
abstract::Hormonal regulation controls mammary gland (MG) development. Therefore some hormone-related factors can disrupt the early phases of MGs development, making the gland more susceptible to long term modifications in its response to circulating hormones. Endocrine disruptors, such as bisphenol A (BPA), are able to cause a...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2019.109918
更新日期:2020-01-30 00:00:00
abstract::High-performance liquid chromatography with electrochemical detection was used to measure N-acetyldopamine and N-acetyl 5-hydroxytryptamine in the cerebral ganglia of the African migratory locust, Locusta migratoria (fifth instar) exposed to lindane, a chlorinated insecticide. Locusts were poisoned by this insecticide...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(90)90050-f
更新日期:1990-08-01 00:00:00
abstract::Phytoremediation is an effective way to repair heavy metal contaminated soil and rhizosphere microorganisms play an important role in plant regulation. Nevertheless, little information is known about the variation of microbial metabolic activities and community structure in rhizosphere during phytoremediation. In this...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.110958
更新日期:2020-10-01 00:00:00
abstract::The release of active pharmaceutical ingredients (APIs) into the environment is of great concern for aquatic ecosystem as many of these chemicals are designed to exert biological activity. Hence, their impact on non-target organisms like fish would not be surprising. In this respect, we revisited fish toxicity data of...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.11.099
更新日期:2019-04-15 00:00:00
abstract::Chromium (Cr) pollution affects plant growth and biochemical processes, so, the relative uptake of glycine, nitrate, and ammonium by pak choi (Brassica chinensis) seedlings in treatments with 0mgL-1 and 10mgL-1 Cr (VI) were detected by substrate-specific 15N-labelling in a sterile environment. The short-term uptake of...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.02.009
更新日期:2017-05-01 00:00:00
abstract::The morphophysiological effects of Cr(VI) on Scenedesmus acutus were studied by light and fluorescence microscopy. Axenic cultures of S. acutus were grown in the presence of 1, 5, and 10 mg/liter of Cr(VI) supplied as K2Cr2O7. It was found that Cr(VI) inhibits cell proliferation and the formation of coenobia. It also ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1993.1008
更新日期:1993-02-01 00:00:00
abstract::An outdoor pot experiment was designed to study the potential of poplar (Populus nigra 'Italica') in phytoremediation of cadmium (Cd) and lead (Pb). Poplar was treated with a combination of different concentrations of Cd (w = 10, 25, 50mgkg-1 soil) and Pb (400, 800, 1200mgkg-1 soil) and several physiological and bioch...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.06.011
更新日期:2017-10-01 00:00:00
abstract::Acute toxic effects on Salmo gairdneri, Poecilia reticulata, Daphnia magna, and the growth inhibition of Selenastrum capricornutum were measured for eight aromatic hydrocarbons. Toxicity measurements were carried out following the OECD standard guidelines modified as appropriate in order to prevent hydrocarbon loss by...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(88)90030-9
更新日期:1988-10-01 00:00:00
abstract::Hematite nanoparticles (α-Fe2O3 NPs) were successfully synthesized by a low-cost solvent-free reaction using Ferrous sulfate waste (FeSO4·7H2O) and pyrite (FeS2) as raw materials and employed for the decolorization of Methyl Orange by the photo-Fenton system. The properties of α-Fe2O3 NPs before and after photo-Fenton...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.110744
更新日期:2020-09-01 00:00:00
abstract::Effects of 17beta-estradiol and p-nonylphenol were examined in the immune and endocrine organs of Japanese quail embryos. The test compounds were injected into the yolk of embryonated eggs. Injection of estrogen resulted in (1) disappearance of lymphoid cells and flattened development of plicae in the bursa of Fabrici...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2005.07.026
更新日期:2006-11-01 00:00:00
abstract::Bisphenol A (BPA) is a widely used chemical that has been extensively studied as an endocrine-disrupting chemical (EDC). Other bisphenols sharing close structural features with BPA, are increasingly being used as alternatives, increasing the need to assess associated hazards to the endocrine system. In the present stu...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.04.009
更新日期:2017-08-01 00:00:00
abstract::Studies showed that DDT levels were still high in Tianjin, China, even though its use was banned in 1983. To estimate current risk of DDT to human health in Tianjin area, a non-steady-state (Level IV) multimedia fugacity model was used to simulate the fate and transfer of p,p'-DDT before and after the ban. The ordinar...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2005.06.003
更新日期:2006-02-01 00:00:00
abstract::Algae blooms frequently occur in the coastal areas of China, and pose numbers of adverse effects to marine environment. Nitzschia closterium is one of the algal species associated with algae blooms and was selected as the target algae of this work. This study was the first attempt to investigate the effect of carbon s...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2019.03.110
更新日期:2019-08-15 00:00:00
abstract::Polybrominated diphenyl ethers (PBDEs) have been used as flame retardants in consumer products and are now found in the aquatic environment. The presence of PBDEs puts the health and survival of aquatic species at risk due to the various toxic effects associated with exposure to these compounds. The effects of a binar...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.07.052
更新日期:2018-11-15 00:00:00
abstract::Coal excavation and refinement processes generate substantial volumes of contaminated effluent that may be detrimental to aquatic ecosystems. As such, understanding the impacts of coal mine water releases on aquatic animals and ecosystems is essential for effectively managing and protecting neighboring environments. S...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2016.03.003
更新日期:2016-07-01 00:00:00
abstract::Biochar has been recently used as an alternative strategy to improve soil quality and plant growth in metal contaminated soils. However, the effects of biochar on gas exchange parameters such photosynthetic rate (A), water use efficiency (WUE) and instantaneous carboxylation efficiency (ICE) in metal tolerant plant sp...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2019.109557
更新日期:2019-11-15 00:00:00
abstract::Aqueous samples containing various nitrated and aminated diphenylamine derivatives were subjected to the luminescent bacterium Vibrio fischeri NRRL-B-11177 to determine their ecotoxicological potential. As the most important toxicological parameter, EC50, the concentration needed to reduce bacterial luminescence by 50...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1995.1055
更新日期:1995-07-01 00:00:00
abstract::In vitro grown Petunia grandiflora and Gaillardia grandiflora plantlets showed 76 percent and 62 percent American Dye Manufacturers Institute value (color) removal from a simulated dyes mixture within 36h respectively whereas their consortium gave 94 percent decolorization. P. grandiflora, G. grandiflora and their con...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2014.01.033
更新日期:2014-05-01 00:00:00
abstract::The purpose of this study was to assess the human cancer risk due to the exposure to the soil-bound polycyclic aromatic hydrocarbons (PAHs) from Chengdu Economic Region (CER), western China with the main concern on cancer risk source apportionment. The total concentrations of sixteen PAHs ranged from 12.5 to 75431 ng ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.04.065
更新日期:2018-09-15 00:00:00
abstract::An oil spill into the River Lambro occurred on 23 February 2010 and reached the Po River the following day. Breams captured here on 1 March 2010, along with a sample from a control site, were examined by light and electron microscopy. The main affected organs were skin and gill with slight or no damage to liver, kidne...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2011.10.014
更新日期:2012-03-01 00:00:00
abstract::The effects of the insecticidal Cry1Ab protein from Bacillus thuringiensis (Bt) on the nematode, Caenorhabditis elegans, were studied with soil from experimental fields cultivated with transgenic Bt corn (MON810) and with trypsinized Cry1Ab protein expressed in Escherichia coli. The content of Cry1Ab protein was above...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2007.10.017
更新日期:2008-06-01 00:00:00
abstract::Extensive industrial activities have led to an increase of the content of chromium in the environment, which causes serious pollution to the surrounding water, soil and atmosphere. The enrichment of chromium in the environment through the food chain ultimately affects human health. Therefore, the remediation of chromi...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章,评审
doi:10.1016/j.ecoenv.2020.111699
更新日期:2021-01-15 00:00:00
abstract::Contamination of the environment by heavy metals has been increasing in recent years due to industrial activities. Thus research involving microorganisms capable of surviving in multi-contaminated environments is extremely important. The objectives of the present study were to evaluate the removal of mercury alone and...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.02.010
更新日期:2017-06-01 00:00:00
abstract::Nonylphenol (NP) is one of commonly detected contaminants in the environment. Biological degradation is mainly responsible for remediation of NP-contaminated site. Knowledge about the structure of NP-degrading microbial community is still very limited. Microcosms were constructed to investigate the structure of microb...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2014.04.019
更新日期:2014-08-01 00:00:00
abstract::The mineralization kinetics of the detergent n-dodecylbenzenesulfonate ([14C]LAS) and the plasticizer di(2-ethylhexyl)phthalate ([14C]DEHP) were studied in three fresh sampled soils of different type. Time series of 14CO2 evolution were fitted with various linear and nonlinear models. The kinetics could be represented...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1996.0066
更新日期:1996-08-01 00:00:00
abstract::Chlorpyrifos (CPF) is a worldwide used pesticide that raises concerns from the environmental and human health perspectives. The presence of pesticides such as CPF in edible vegetables has been already reported, but little is known about the effects induced by this pesticide stress on the morphology, oxidative response...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2018.03.005
更新日期:2018-07-30 00:00:00
abstract::In nematodes, 10 J/m(2)/min of UV irradiation induced a mild reproductive toxicity. Pre-treatment with UV irradiation at 10 J/m(2)/min suppressed the formation of reproductive defects, and activated a noticeable reduction of percentage of population with hsp-16.2::gfp expression, an obvious elevation of superoxide dis...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2009.12.014
更新日期:2010-03-01 00:00:00
abstract::Honeybees (Apis mellifera) play an important role in agriculture worldwide. Several factors including agrochemicals can affect honey bee health including habitat fragmentation, pesticide application, and pests. The growing human population and subsequent increasing crop production have led to widespread use of agroche...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2020.111108
更新日期:2020-11-01 00:00:00
abstract::The concentrations and biomagnifications of dichlorodiphenyltrichloroethane (DDT) and its metabolites were examined in four fish species (Clarias gariepinus, Oreochromis niloticus, Tilapia zillii, and Carassius auratus) from Lake Ziway, Rift Valley, Ethiopia. Paired stomach content analysis, and stable isotope ratio o...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2013.03.020
更新日期:2013-09-01 00:00:00