Abstract:
:The results obtained in 14 patients suffering from hormone-resistant metastatic breast cancer treated with the following association: methotrexate (5-fluorouracyl in case of methotrexate intolerance), cyclophosphamide, vinblastin administered i.v. once every 10-13 days, are reported. 4 objective regression (29%) were observed but survival did not very appreciably differing therapy. In 9 cases (65%) intolerance of various types was observed but in 8 these signs regressed in a short time and the therapy was resumed.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Pipino G,Germiniani R,Lavorato Fsubject
Has Abstractpub_date
1977-03-17 00:00:00pages
835-7issue
13eissn
0026-4806issn
1827-1669journal_volume
68pub_type
临床试验,杂志文章相关文献
MINERVA MEDICA文献大全abstract:AIM:The aim of this paper was to evaluate the effect of carbon dioxide (CO2) vs. air insufflation on post-endoscopic retrograde cholangiopancreatography (ERCP) abdominal pain and distension. In addition, we investigated the changes in the partial pressure of end-tidal CO2 (PetCO2) and the partial pressure of arterial C...
journal_title:Minerva medica
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2011-08-01 00:00:00
abstract::The subject of this dissertation is the diet of flight personnel. A rapid review of the general question of diet in general and that of flight personnel in particular is given. On this basis, the various aspects of the problem (energy sources, calorie requirements, activity of the individual, etc.) are examined. The c...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1982-08-25 00:00:00
abstract::Measurements of oxygen consumption, ventilation and dynamic respiratory work in three males during ergometer bicycle exercise at sea level and at 3500 m altitude are reported. At submaximal work load, dynamic respiratory work proved 140-180% greater at 3500 m than at sea level; at a given ventilation, on the other han...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1981-10-06 00:00:00
abstract::The bacterium Helicobacter pylori (H. pylori), prime causal agent of gastroduodenal diseases, has been involved in various aspects of several extragastric manifestations. Although currently available data do not provide proof of its role in most of them, a potential relationship cannot be ruled out. In the present rev...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:2010-04-01 00:00:00
abstract::Cytology using fine needle aspiration biopsy has been widely used in dysplastic and neoplastic thyroid lesions as it is free of complications and very accurate. Personal experience with 2212 thyroid fine needle aspiration biopsies (1564 patients) performed in the period 1983-1987 is reported. Cytologic and histologic ...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1989-05-01 00:00:00
abstract::The Authors report their experience with the placebo, an essential step in the clinical study of reflexotherapy. They assert that also in this branch of medicine it is possible to carry out a "double blind" clinical experimentation by means of placebo, that is, an essential condition in order to develop a scientific a...
journal_title:Minerva medica
pub_type: 临床试验,杂志文章
doi:
更新日期:1980-03-31 00:00:00
abstract::After a brief survey of the various modifications that may be encountered by drugs through the work of systems that detoxify the liver cell, attention is given to the problem of enzymic induction. The latter is the result of derepression of a gene that codes for a given enzyme; at the molecular level, derepression tak...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1976-09-29 00:00:00
abstract::In this review, the Authors analyzes the more recent data in the Literature about the major cardiovascular risks in diabetic patients affected by systemic arterial hypertension. The more effective pharmacological and not pharmacological treatment is suggested. Particularly the advantages and more important side-effect...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:1992-11-01 00:00:00
abstract::Among 1258 polyps from the lower gastro-intestinal tract removed by rectoscopy or coloscopy and examined histologically there were 744 adenomas, 72% tubular, 27% papillary and 1% villous. 96.5% of all adenomas were extracted from patients aged over 40 years. Four fifths of the tumours were found in the rectum and sigm...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1978-11-30 00:00:00
abstract::A group of 104 workers were examined. They were employed in selecting rags and separating the lining from wollen fabrics to be used again as thread waste in the textile industry. The aim of the study was to point out tendon and joint related disorders of the upper limb due to repetitive and forced movements. Twenty-ei...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:1995-11-01 00:00:00
abstract::Intranasal desmopressin represents the treatment of choice in Central Diabetes Insipidus. Nevertheless, this route of administration bears some practical disadvantage, linked to either difficult delivering technique, or the status of nasal mucose. The antidiuretic effectiveness of oral desmopressin has been recently d...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::The frequency of thyroid alterations was examined and dietary iodine intake was assessed via urinary iodine in 6-15 yr-old schoolchildren from 145 towns in Piedmont and the Aosta Valley. Local food iodine values were also determined in 56 towns. Alteration frequency and daily urinary elimination of iodine were inverse...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1975-10-17 00:00:00
abstract::Conventional conservative treatment of chronic uremia is aimed at reducing protein intake to a minimum level compatible with nitrogen balance. A great progress in this field is represented by a low protein diet associated with some essential aminoacids and ketoanalogues. A group of 20 patients with chronic renal failu...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1980-09-19 00:00:00
abstract:AIM:Corticosteroids, antidopaminergig agents and 5-HT3 antagonists are the most commonly used drugs in the treatment of chemotherapy-induced vomiting. Acupuncture and acupressure have also appeared to exert antiemetic effects. The aim of this study was to evaluate the efficacy of acupressure in the treatment of chemoth...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:2006-10-01 00:00:00
abstract::Treatment of chronic hepatitis B has shown a rapid development in the last years leading to a shift of treatment strategies from interferon to hepatitis B virus (HBV)-polymerase inhibitors. In particular, treatment with HBV-polymerase inhibitors has changed the indication on how to treat a patient and when to stop the...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:2009-12-01 00:00:00
abstract::The preoperative diagnosis of carcinoma of the gallbladder is very difficult because the clinical manifestations of this disease are nonspecific and often indistinguishable from those of cholecystitis. Radiography, including oral cholecystograms and i.v. cholangiograms, give aspecific findings. Ultrasound scans were p...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::Non-ketonic hyperosmolar hyperglycaemic coma (N.K.H.H.C.) is by no means uncommon in diabetes. Its picture includes sensorial depression, hyperglycaemia, hyperazotemia, marked dehydration and plasma hyperosmolarity. It is mostly found in elderly subjects with non-serious diabetes. Reference is made to 6 personal cases...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1976-02-18 00:00:00
abstract::A brief report on the role of neurotransmittors (especially dopamine) depletion in cerebral aging and the development of certain pathological conditions in the elderly is presented. This is followed by a report on the results obtained by the administration of citicoline (500 mg/per diem intramuscularly for 20 days) to...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1983-04-07 00:00:00
abstract::15 male heroin addicts, 19-26 yr, were given 20 hospital treatments for detoxifying. Therapeutic program was based on GABAergic drugs (1-glutamine, sodium valproate, pyridoxine), low doses psychodrugs and acupuncture, added from the 3rd day. A full avoidance of the withdrawal syndrome was reached in 15 out of 18 Ss so...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1982-03-31 00:00:00
abstract::PRA (in the supine and erect subject) and urinary sodium before and after acute treatment (100 mg i.m.) and chronic treatment (100 mg per os for 8 days) were examined in two groups of subjects with no signs of cardiovascular or renal disease. It was found that indomethacin, which is a well-known inhibitor of prostagla...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1978-09-15 00:00:00
abstract::In the present work receptors for polymerized rat serum albumin (P-RSA) were studied by incubation of radiolabelled polymers with rat hepatocytes isolated with mechanical techniques. Isolated rat hepatocytes showed a receptor activity for polymerized albumin and such a membrane receptor seems to be controlled by the c...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract::Thyroid disorders include autoimmune thyroid diseases (AITD), thyroid goiter, nodule and cancer. AITD mainly consist of autoimmune thyroiditis and Graves disease. The common characteristic of thyroid disorders is female preponderance in their prevalence. The female-to-male rate ratio is reported at 4~6:1 for AITD and ...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:2015-04-01 00:00:00
abstract::Penile systolic pressure has been evaluated by the Doppler-sonographic method in 15 diabetic patients suffering from erectile impotence. Urodynamic tests have also been carried out in some patients for a diagnosis of neurological impotence. The results obtained show the possibility of a double or sole origin (neurogen...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1981-12-08 00:00:00
abstract::The Authors report their experience on a series of 125 patients that underwent stereotactic biopsy. The procedure has proved reliable and almost risk -free. The diagnosis obtained from the bioptic specimen by smear technique-cytological examination and by paraffin embedding-histological examination are compared. Neuro...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1984-05-19 00:00:00
abstract::Numerous factors may influence the sympathetic and pressure response to physical exercise, age, sex, type of activity carried on and training for example. Training, in particular is considered to reduce both adrenergic and pressure response. Plasma catecholamine levels and the haemodynamic response to the hand-grip te...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00
abstract::308 mammary needle aspirations for suspected clinical forms of mammary cystitis were performed between 1971 and 1980 at the Savona Oncological Centre. The evacuated cystic cavity was always treated with a concentrated Lugol solution, the sclerosing and modifying properties of which foster wall adherence and prevent re...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1982-11-17 00:00:00
abstract:BACKGROUND:This study aims to provide a reference for the clinical treatment of patients with spleen ruptures by analyzing and discussing the clinical effects of the conservative treatment. METHODS:The clinical data of 93 patients with blunt spleen rupture treated in the First Affiliated Hospital of University of Scie...
journal_title:Minerva medica
pub_type: 杂志文章
doi:10.23736/S0026-4806.20.06574-X
更新日期:2020-05-29 00:00:00
abstract::It is possible to carry out percutaneous injections of lesions in any organ under the direction of echography. This is particularly so in the liver, pancreas and kidney. The procedure has been used in 79 patients for diagnostic and/or therapeutic purposes and has provided very good and promising results. The technique...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1981-04-02 00:00:00
abstract::An examination was made of the series of 439 lung tumours diagnosed ambulatorially at the Turin Social Health Dispensary to assess the diagnostic return from several techniques (cytology of the sputum, bronchial aspirate and brushing; histology on a biopsy specimen) used singly or in combination. It was also sought to...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1984-09-08 00:00:00
abstract::A case of pleuropulmonary manifestation as the first symptom of rheumatoid arthritis is reported; articular involvement followed at a later stage. Pleuropulmonary localisation of rheumatoid arthritis is varied and infrequent; it is seldom the first manifestation of illness. This case was particular because isolated pl...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00