Abstract:
OBJECTIVE:To determine the short- (4 weeks) and long-term (6 month) effectiveness of Tibetan medicated bathing therapy in patients with post-stroke limb spasticity. DESIGN:Prospective, blinded, randomized controlled trial. SUBJECTS:Post-stroke patients with limb spasticity were recruited between December 2013 and February 2017 and randomly assigned 1:1 to a control group that received conventional rehabilitation (n = 222) or an experimental group that received Tibetan medicated bathing therapy in combination with conventional rehabilitation (n = 222). METHODS:All patients received conventional rehabilitation. In addition, the experimental group received Tibetan medicated bathing therapy. The interventions were conducted 5 times per week for 4 weeks. The primary endpoint was changes from baseline after 4 weeks of therapy in muscle tone in the spastic muscles (elbow flexors, wrist flexors, finger flexors, knee extensors, ankle plantar flexors), as measured by the Modified Ashworth Scale (MAS). RESULTS:The mean change from baseline after 4 weeks of therapy in the MAS score for the elbow flexors (P = .017), wrist flexors (P < .001), and ankle plantar flexors (P < .001) was significantly greater in patients in the experimental group compared to the control group. The benefit was maintained for 3 muscle groups (elbow flexors P < .001, wrist flexors P = .001, and ankle plantar flexors P < .001) and 6 months (elbow flexors P < .001, wrist flexors P = .002, and ankle plantar flexors P < .001) after therapy. All adverse events were mild, and no serious adverse reactions to Tibetan medicated bathing therapy were recorded. CONCLUSIONS AND IMPLICATIONS:Tibetan medicated bathing therapy, in combination with conventional rehabilitation, has potential as a safe, effective treatment for the alleviation of post-stroke upper limb spasticity. Tibetan medicated bathing therapy was most advantageous for patients who had a baseline muscle tone score of 1+ to 2 on the MAS in the affected limb and recent onset of stroke (duration of the disease of 1-3 months).
journal_name
J Am Med Dir Assocjournal_title
Journal of the American Medical Directors Associationauthors
Wang M,Liu S,Peng Z,Zhu Y,Feng X,Gu Y,Sun J,Tang Q,Chen H,Huang X,Hu J,Chen W,Xiang J,Wan C,Fan G,Lu J,Xia W,Lihua Wang,Steven Y Cheng,Lu X,Li Jdoi
10.1016/j.jamda.2019.10.018subject
Has Abstractpub_date
2020-03-01 00:00:00pages
374-380.e4issue
3eissn
1525-8610issn
1538-9375pii
S1525-8610(19)30769-8journal_volume
21pub_type
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journal_title:Journal of the American Medical Directors Association
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journal_title:Journal of the American Medical Directors Association
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journal_title:Journal of the American Medical Directors Association
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pub_type: 共识发展会议,杂志文章,评审
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pub_type: 杂志文章,评审
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journal_title:Journal of the American Medical Directors Association
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