当前位置： SCI文献检索 > CROATIAN MEDICAL JOURNAL期刊下所有文献 > Interleukin 1 level, cognitive performance, and severity of depressive symptoms in patients treated with systemic anticancer therapy: a prospective study.

Interleukin 1 level, cognitive performance, and severity of depressive symptoms in patients treated with systemic anticancer therapy: a prospective study.

Abstract：

AIM:To assess the relationship between cognitive functions, severity of depressive symptoms, and expression of interleukin 1 (IL)-1 in patients treated with systemic anticancer therapy. METHODS:This prospective study, conducted in 2017-2018, involved 55 patients (56% men) subjected to systemic anticancer therapy. Forty-one patients had lung cancer (74.55%) and 14 had breast cancer (25.45%). Patients' mean age was 55.5±9.3 (from 26 to 65 years). Neuropsychological tests were conducted twice: on the day of qualifying for the study before the start of chemotherapy and after the end of the full treatment cycle. We assessed patients' cognitive functioning using Trail Making Test A&B (TMT), Stroop Color-Word Interference Test, and Verbal Fluency Test (VFT). Severity of depressive symptoms and the level of IL-1 expression were also examined. RESULTS:After chemotherapy, patients had significantly lower expression of IL-1α (P<0.005) and IL-1β (P<0.001) at the protein level. They also had lower severity of depressive symptoms (borderline significant, P=0.063), needed more time to complete the first part of the Stroop test (P=0.03), and had worse score on the first part of the VFT (P<0.001). Before chemotherapy there was a significant negative correlation between IL-1β expression and the speed at which the first part of the TMT test was completed. CONCLUSIONS:The severity of depressive symptoms after chemotherapy was lower than before chemotherapy. Patients' cognitive performance did not significantly deteriorate after chemotherapy, except the performance at the first part of the Stroop test and the first part of the VFT.

journal_name

Croat Med J

journal_title

Croatian medical journal

authors

Jasionowska J,Talarowska M,Kalinka E,Skiba A,Szemraj J,Mikołajczyk I,Gałecki P

subject

Has Abstract

pub_date

2019-04-30 00:00:00

pages

166-173

issue

2

eissn

0353-9504

issn

1332-8166

journal_volume

60

pub_type

杂志文章

相关文献

CROATIAN MEDICAL JOURNAL文献大全
  • Y-chromosome short tandem repeat intermediate variant alleles DYS392.2, DYS449.2, and DYS385.2 delineate new phylogenetic substructure in human Y-chromosome haplogroup tree.

    abstract：AIM:To determine the human Y-chromosome haplogroup backgrounds of intermediate-sized variant alleles displayed by short tandem repeat (STR) loci DYS392, DYS449, and DYS385, and to evaluate the potential of each intermediate variant to elucidate new phylogenetic substructure within the human Y-chromosome haplogroup tree...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2009.50.239

    authors： Myres NM,Ritchie KH,Lin AA,Hughes RH,Woodward SR,Underhill PA

    更新日期：2009-06-01 00:00:00

  • Psychosomatic and depressive symptoms in civilians, refugees, and soldiers: 1993-2004 longitudinal study in Croatia.

    abstract：AIM:To evaluate psychosomatic complaints and depressive symptoms among civilians, refugees, and soldiers in the war and post-war period in Croatia. METHOD:The design of the study was longitudinal, including four repeated assessments during the war and post-war period (1993, 1995, 2000, and 2004). The baseline assessme...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Proroković A,Cavka M,Cubela Adorić V

    更新日期：2005-04-01 00:00:00

  • Haplotype data for 23 Y-chromosome markers in a reference sample from Bosnia and Herzegovina.

    abstract：AIM:To detect polymorphisms of 23 Y-chromosomal short tandem repeat (STR) loci, including 6 new loci, in a reference database of male population of Bosnia and Herzegovina, as well as to assess the importance of increasing the number of Y-STR loci utilized in forensic DNA analysis. METHODS:The reference sample consiste...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2013.54.286

    authors： Kovačević L,Fatur-Cerić V,Hadzic N,Čakar J,Primorac D,Marjanović D

    更新日期：2013-06-01 00:00:00

  • "Complementary and alternative" medicine--a measure of crisis in academic medicine.

    abstract：:Academic medicine integrates three of the most honorable human activities: treating the ill, teaching, and research. The quality that all three share is persistent quest for truth. However, there is reluctance of academic medicine today to openly defend scientific truth by challenging the arguments and the very existe...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Marusic M

    更新日期：2004-12-01 00:00:00

  • Body mass index and nutrition as determinants of health and disease in population of Croatian Adriatic islands.

    abstract：AIM:To investigate the relationships between body mass index (BMI), dietary habits, and cardiovascular risk factors in isolated Adriatic island populations of Croatia. METHODS:Random sample of subjects (n=1001) was interviewed, using a validated questionnaire developed for this research program. Dietary habits were as...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Pucarin-Cvetković J,Mustajbegović J,Doko Jelinić J,Senta A,Nola IA,Ivanković D,Kaić-Rak A,Milosević M

    更新日期：2006-08-01 00:00:00

  • Kidney transplantation using a colon pouch (Mainz pouch III): a case report.

    abstract：:Kidney transplantation is the most efficient method of renal replacement therapy. When this method is performed, native urinary bladder is the preferred urinary reservoir. However, in some patients with an anatomically and functionally abnormal lower urinary tract, the urinary bladder cannot be used for transplantatio...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Markić D,Oguić R,Krpina K,Gršković A,Vukelić I,Rački S,Ivančić A,Primc D,Španjol J

    更新日期：2019-12-31 00:00:00

  • Utilizing DNA analysis to combat the world wide plague of present day slavery--trafficking in persons.

    abstract：:A study was conducted to determine if modern forensic DNA typing methods can be properly employed throughout the world with a final goal of increasing arrests, prosecutions, and convictions of perpetrators of modern day trafficking in persons while concurrently reducing the burden of victim testimony in legal proceedi...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2014.55.3

    authors： Palmbach TM,Blom J,Hoynes E,Primorac D,Gaboury M

    更新日期：2014-02-01 00:00:00

  • Common variant in myocilin gene is associated with high myopia in isolated population of Korcula Island, Croatia.

    abstract：AIM:To study the association between genetic variants in myocilin and collagen type I alpha 1 genes and high myopia in an isolated island population. METHODS:A total of 944 examinees from the genetic epidemiology study conducted on the island of Korcula, Croatia, were included in the study. We selected 2 short nucleot...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2009.50.17

    authors： Vatavuk Z,Skunca Herman J,Bencić G,Andrijević Derk B,Lacmanović Loncar V,Petric Vicković I,Bucan K,Mandić K,Mandić A,Skegro I,Pavicić Astalos J,Merc I,Martinović M,Kralj P,Knezević T,Barać-Juretić K,Zgaga L

    更新日期：2009-02-01 00:00:00

  • Possible transfusion-related acute lung injury (TRALI) in cardiac surgery patients.

    abstract：AIM:To determine the incidence of possible transfusion-related acute lung injury (TRALI) and related risk factors in cardiac surgery patients. METHODS:A single-center prospective cohort study was conducted from January 2009 to March 2010 at the Zagreb University Hospital Center, Croatia. Patient-, transfusion-, and su...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2014.55.138

    authors： Zah-Bogovic T,Mesaric J,Hrabac P,Majeric-Kogler V

    更新日期：2014-04-01 00:00:00

  • Prevalence of multiple sclerosis in Croatia: data from national and non-governmental organization registries.

    abstract：AIM:To update the estimate of multiple sclerosis (MS) prevalence in Croatia using multiple epidemiological tools. METHODS:This level IV, epidemiological study gathered data from three national patient registries and one database of a non-governmental MS patients' organization. Data were extracted on all individuals wh...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2018.59.65

    authors： Benjak T,Štefančić V,Draušnik Ž,Cerovečki I,Roginić D,Habek M,Mihel S,Stevanović R

    更新日期：2018-04-30 00:00:00

  • Double incompatibility at human alpha fibrinogen and penta E loci in paternity testing.

    abstract：:We present a paternity testing case in which a double incompatibility was found for two short tandem repeat (STR) markers, human fibrinogen alpha (FGA) and Penta E. Analysis of the trio (mother, father, and daughter) included the amplification with a battery of 15 autosomal short tandem repeats (STR) by using a commer...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Nutini AL,Mariottini A,Giunti L,Torricelli F,Ricci U

    更新日期：2003-06-01 00:00:00

  • Epidemiology of central nervous system tumors in Labin area, Croatia, 1974-2001.

    abstract：AIM:To establish the incidence of tumors of the central nervous system (CNS) in the population of Labin area in Istria, Croatia, characterized by very little population migration. METHOD:We retrospectively analyzed data on 175 patients (102 men and 73 women) diagnosed with CNS tumor according to the World Health Organ...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Materljan E,Materljan B,Sepcić J,Tuskan-Mohar L,Zamolo G,Erman-Baldini I

    更新日期：2004-04-01 00:00:00

  • Transvaginal color doppler ultrasound in the conservative treatment and surveillance of three ectopic pregnancies.

    abstract：:We evaluated the role of transvaginal color Doppler ultrasound in the treatment and follow-up after transvaginal instillation of methotrexate in ectopic pregnancy. Three patients diagnosed with ectopic pregnancies were treated with a single 50 mg dose of methotrexate, transvaginally instilled, under direct color sonog...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Plancher S,Conway C,Zalud I

    更新日期：1998-06-01 00:00:00

  • Challenge of goodness III: public health facing war.

    abstract：:Using moral and empirical analysis, we analyzed and discussed the role of public health in prevention of war as well as its function during and after the war. The idea is to develop a theory and new strategy in the spirit of public health to improve practices in preserving and strengthening peace, to be prepared for t...

    journal_title：Croatian medical journal

    pub_type： 杂志文章,评审

    doi：

    authors： Lang S,Kovacić L,Sogorić S,Brborović O

    更新日期：2002-04-01 00:00:00

  • Academic medicine--experiences from Finland and suggestions for the future.

    abstract：:This article presents the basic facts about education, health care system, and academic medicine in Finland. The issue of the academic medicine in the world is discussed and Finnish models compared with those of the rest of the world. Possible solutions for the recovery of academic medicine, education, and research ar...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Stefanović V

    更新日期：2004-06-01 00:00:00

  • When autosomal short tandem repeats fail: optimized primer and reaction design for Y-chromosome short tandem repeat analysis in forensic casework.

    abstract：:Y-chromosomal short tandem repeats (Y-STRs) are useful forensic DNA markers in investigation of sexual assault cases when a mixture of male and female DNA (e.g., in vaginal swabs) is present in a sample, especially when DNA of the male contributor is present only in very small amount compared to the DNA of the female ...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Parson W,Niederstätter H,Köchl S,Steinlechner M,Berger B

    更新日期：2001-06-01 00:00:00

  • Educating science editors: is there a comprehensive strategy?

    abstract：:The article considers available options to educate science editors in the fast-transforming digital environment. There is no single course or resource that can cover their constantly changing and diversifying educational needs. The involvement in research, writing, and reviewing is important for gaining editing skills...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2014.55.672

    authors： Gasparyan AY,Yessirkepov M,Gorin SV,Kitas GD

    更新日期：2014-12-01 00:00:00

  • A validation of the Croatian version of Zarit Burden Interview and clinical predictors of caregiver burden in informal caregivers of patients with dementia: a cross-sectional study.

    abstract：AIM:To validate the Croatian version of the Zarit Burden Interview (ZBI) and to investigate the predictors of perceived burden. METHODS:This cross-sectional study involved 131 dyads of one informal caregiver family member and one patient with dementia visiting primary care practices (Health Care Center Zagreb-West; 10...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Lucijanić J,Baždarić K,Librenjak D,Lucijanić M,Hanževački M,Jureša V

    更新日期：2020-12-31 00:00:00

  • Medical audit of diabetes mellitus in primary care setting in Bosnia and Herzegovina.

    abstract：AIM:To assess the quality of diabetes care provided by family medicine teams in primary health centers in Bosnia and Herzegovina (BH) through a medical audit, addressing the extent to which clinical practice complied with pre-determined explicit criteria of long-term management. METHOD:Retrospective analysis included ...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2008.49.757

    authors： Novo A,Jokić I

    更新日期：2008-12-01 00:00:00

  • Professionals with delivery skills: backbone of the health system and key to reaching the maternal health Millennium Development Goal.

    abstract：:The attainment of the fifth Millennium Development Goal requires adequate national reserves of skilled birth attendants. Nurses, midwives, and their equivalents form the frontline of the formal health system are a critical element of global efforts to reduce ill-health and poverty in the poorest areas of the world. Pl...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2008.3.318

    authors： Wirth M

    更新日期：2008-06-01 00:00:00

  • Impact of ovariectomy, high fat diet, and lifestyle modifications on oxidative/antioxidative status in the rat liver.

    abstract：AIM:To estimate the impact of high fat diet and estrogen deficiency on the oxidative and antioxidative status in the liver of the ovariectomized rats, as well as the ameliorating effect of physical activity or consumption of functional food containing bioactive compounds with antioxidative properties on oxidative damag...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2014.55.218

    authors： Vuković R,Blažetić S,Oršolić I,Heffer M,Vari SG,Gajdoš M,Krivošíková Z,Kramárová P,Kebis A,Has-Schön E

    更新日期：2014-06-01 00:00:00

  • Unlinked anonymous monitoring of human immunodeficiency virus prevalence in high- and low-risk groups in Slovenia, 1993-2002.

    abstract：AIM:To determine the prevalence of human immunodeficiency virus (HIV) infection in high-risk groups, ie, injecting drug users, patients with sexually transmitted infections, and men who have sex with men, and compare it with the prevalence determined in low-risk group, ie, pregnant women. METHODS:Residual sera from sp...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Klavs I,Poljak M

    更新日期：2003-10-01 00:00:00

  • Treatment outcomes and perception of social acknowledgment in war veterans: follow-up study.

    abstract：AIM:To assess treatment outcomes of psychotherapy for war veterans suffering from posttraumatic stress disorder (PTSD) and to investigate self-perceived social acknowledgment. METHODS:In this prospective cohort study, a set of psychological instruments was used to assess the level of posttraumatic stress symptoms (Cli...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Ljubotina D,Pantić Z,Francisković T,Mladić M,Priebe S

    更新日期：2007-04-01 00:00:00

  • Conscience in health care and the definitions of death.

    abstract：:Brain death or neurologic death has gradually become recognized as human death over the past decades worldwide. Nevertheless, in Japan, the New York State, and the State of New Jersey, death is declared based not on brain death criteria, but on cardio-pulmonary criteria. In Japan, the 1997 Organ Transplant Law legaliz...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2013.54.75

    authors： Kato Y

    更新日期：2013-02-01 00:00:00

  • International pediatric cardiac assistance in Croatia: results of the 10 year program.

    abstract：AIM:In an effort to help alleviate the lack of an adequate pediatric cardiac surgical service that existed in Croatia following 1991 the International Childrens Heart Foundation (ICHF) was asked to provide the necessary surgery. Initially, this project was undertaken as a humanitarian program to provide pediatric cardi...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Novick WM,Anić D,Ivancan V,Di Sessa TG

    更新日期：2004-08-01 00:00:00

  • Starling forces drive intracranial water exchange during normal and pathological states.

    abstract：AIM:To quantify the exchange of water between cerebral compartments, specifically blood, tissue, perivascular pathways, and cerebrospinal fluid-filled spaces, on the basis of experimental data and to propose a dynamic global model of water flux through the entire brain to elucidate functionally relevant fluid exchange ...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2017.58.384

    authors： Linninger AA,Xu C,Tangen K,Hartung G

    更新日期：2017-12-31 00:00:00

  • Changes in human immunodeficiency virus and sexually transmitted infections-related sexual risk taking among young Croatian adults: 2005 and 2010 population-based surveys.

    abstract：AIM:To determine changes in sexual behaviors and other relevant characteristics related to human immunodeficiency virus (HIV) and sexually transmitted infection (STI) risks among young Croatian adults. METHOD:We surveyed adults aged 18-24 in 2005 (n=1092) and 18-25 in 2010 (n=1005). Both samples were probabilistic and...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：10.3325/cmj.2011.52.458

    authors： Landripet I,Stulhofer A,Bacak V

    更新日期：2011-08-15 00:00:00

  • Navigating Knowledge Landscapes in the digital society: a look back and visions for the future.

    abstract：: ...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Svalastog AL,Allgaier J,Gajović S

    更新日期：2018-10-31 00:00:00

  • Phthalates in underground waters of the Zagreb area.

    abstract：AIM:To determine whether and in what concentrations the underground waters, stream waters, spring water, and tap water from the Zagreb area contain phthalates -- compounds used as plastic softeners, which have recently been ascribed carcinogenic, mutagenic, and teratogenic effects. METHOD:The presence of dimethyl phth...

    journal_title：Croatian medical journal

    pub_type： 杂志文章

    doi：

    authors： Mihovec-Grdić M,Smit Z,Puntarić D,Bosnir J

    更新日期：2002-08-01 00:00:00

  • Myocardial protective effect of warm blood, tepid blood, and cold crystalloid cardioplegia in coronary artery bypass grafting surgery.

    abstract：AIM:To compare the myocardial effects of cardioplegia by warm blood, tepid blood, and cold crystalloid during coronary artery bypass grafting (CABG). METHODS:Patients undergoing CABG surgery at Kaunas University Hospital between 2000 and 2004 were randomized into three groups (n=156), receiving a different method of c...

    journal_title：Croatian medical journal

    pub_type： 杂志文章,随机对照试验

    doi：

    authors： Sirvinskas E,Nasvytis L,Raliene L,Vaskelyte J,Toleikis A,Trumbeckaite S

    更新日期：2005-12-01 00:00:00