Common variant in myocilin gene is associated with high myopia in isolated population of Korcula Island, Croatia.

Abstract:

AIM:To study the association between genetic variants in myocilin and collagen type I alpha 1 genes and high myopia in an isolated island population. METHODS:A total of 944 examinees from the genetic epidemiology study conducted on the island of Korcula, Croatia, were included in the study. We selected 2 short nucleotide polymorphisms (SNP) available in our genome-wide scan set of SNPs that were previously associated with high myopia and used them to replicate previous claims of possible association. RESULTS:Nineteen cases of high myopia, defined as the refraction of

journal_name

Croat Med J

journal_title

Croatian medical journal

authors

Vatavuk Z,Skunca Herman J,Bencić G,Andrijević Derk B,Lacmanović Loncar V,Petric Vicković I,Bucan K,Mandić K,Mandić A,Skegro I,Pavicić Astalos J,Merc I,Martinović M,Kralj P,Knezević T,Barać-Juretić K,Zgaga L

doi

10.3325/cmj.2009.50.17

subject

Has Abstract

pub_date

2009-02-01 00:00:00

pages

17-22

issue

1

eissn

0353-9504

issn

1332-8166

journal_volume

50

pub_type

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