Abstract:
BACKGROUND:Application of adipose-derived stem cells originated from buccal fat pad (BFP) can simplify surgical procedures and diminish clinical risks compared to large autograft harvesting. PURPOSE:This study sought to evaluate and compare the efficacy of buccal fat pad-derived stem cells (BFPSCs) in combination with anorganic bovine bone mineral (ABBM) for vertical and horizontal augmentation of atrophic posterior mandibles. MATERIALS AND METHODS:Fourteen patients with atrophic posterior mandible were elected for this prospective exploratory study. BFP (3-5 mL) was harvested and BFPSCs were isolated and combined with ABBM at 50% ratio. The vertical and horizontal alveolar deficiencies were augmented by 50% mixture of ABBM with either BFPSCs (group 1) or particulated autologous bone (group 2). Titanium mesh was contoured to the desired 3D shape of the alveolar ridge and fixated to the host sites over the graft material of the two groups. At first, the amount of new bone areas was calculated by quantitative analysis of cone beam computed tomography (CBCT) images that were taken 6 months postoperatively according to regenerative techniques (group 1 vs group 2 without considering the type of bone defects). Second, these amounts were calculated in each group based on the type of defects. RESULTS:Quantitative analysis of CBCT images revealed the areas of new bone formation were 169.5 ± 5.90 mm2 and 166.75 ± 10.05 mm2 in groups 1 and 2, respectively. The area of new bone formation for vertical defects were 164.91 ± 3.74 mm2 and 169.36 ± 12.09 mm2 in groups 1 and 2, respectively. The area of new bone formation for horizontal deficiencies were 170.51 ± 4.54 mm2 and 166.98 ± 9.36 mm2 in groups 1 and 2, respectively. There were no statistically significant differences between the two groups in any of the pair-wise comparisons (P > 0.05). CONCLUSIONS:The findings of the present study demonstrated lack of difference in bone volume formation between BFPSCs and autologous particulate bone in combination with ABBM. If confirmed by future large-scale clinical trial, BFPSCs may provide an alternative to autogenous bone for reconstruction of alveolar ridge defects.
journal_name
Clin Implant Dent Relat Resjournal_title
Clinical implant dentistry and related researchauthors
Khojasteh A,Hosseinpour S,Rezai Rad M,Alikhasi M,Zadeh HHdoi
10.1111/cid.12729subject
Has Abstractpub_date
2019-04-01 00:00:00pages
292-300issue
2eissn
1523-0899issn
1708-8208journal_volume
21pub_type
杂志文章abstract:BACKGROUND:In oral implantology there has been a general trend away from machine-turned minimally rough and acid-etched and blasted implants toward intermediary roughened surfaces. Mechanical interlocking at micron resolution is claimed to be the dominant reason for the fixation of such implants in bone. However, clini...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2004.tb00032.x
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Consistent bone changes occur after tooth removal, often compromising the success of implants placed within the socket left to natural healing The long-term effect of ridge preservation on implant outcomes is still unclear. PURPOSE:The aim of the study was to assess success and survival rates of implants pl...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章,随机对照试验
doi:10.1111/cid.12682
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Studies assessing clinical and radiographic peri-implant parameters around short dental implants (SDIs) in treated generalized aggressive periodontitis (GAgP) patients are scant. OBJECTIVES:This 3-year follow-up study aimed to compare the clinical peri-implant and radiographic bone status around SDIs placed...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12761
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:The technical development of digital processing allows the production of anatomically full-contoured implant-supported restorations. PURPOSE:The aim of this prospective clinical trial was to analyze the treatment concept of monolithic lithium disilicate (LS2) single-unit restorations in a complete digital w...
journal_title:Clinical implant dentistry and related research
pub_type: 临床试验,杂志文章
doi:10.1111/cid.12472
更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:The effects of the locations of dental implants on treatment outcomes, as evaluated by oral health-related quality of life (OHRQoL) assessment, remain controversial. PURPOSE:To investigate the association between the locations of dental implants and changes in OHRQoL. MATERIALS AND METHODS:Sixty-eight subj...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12497
更新日期:2017-08-01 00:00:00
abstract:PURPOSE:The purpose of this prospective follow-up study was to evaluate survival and success of early-loaded implants placed in the edentulous mandible and the survival of the fixed dental prostheses (FDPs) after in mean 7.2 years. MATERIALS AND METHODS:Thirty-seven patients (mean age 64.5 years, 18.9% male) received ...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12062
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Peri-implantitis is an infection of the implant surface caused by adhesion of bacteria that generate bone resorption and sometimes even consequent implant loss. Both screw-retained and cemented fixed implants are affected. PURPOSE:The purpose of this study is to investigate the morphological defects at the ...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12133
更新日期:2015-01-01 00:00:00
abstract:BACKGROUND:Although most implant systems have been designed for a two-stage surgical technique, a one-stage surgical technique has always been advocated for the ITI Dental Implant System (Straumann AG, Waldenburg, Switzerland). A new generation of ITI implants was presented in 1988 and included a hollow cylinder, a hol...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2001.tb00125.x
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to document the long-term outcome of Brånemark implants installed in augmented maxillary bone and to identify parameters that are associated with peri-implant bone level. MATERIAL AND METHODS:Patients of a periodontal practice who had been referred to a maxillofacial surgeon for i...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2011.00359.x
更新日期:2013-02-01 00:00:00
abstract:BACKGROUND:Accurate recording of implant location is required so that definitive restorations are properly supported and do not place additional stresses on the implants. Movement of impression copings inside the impression material using an open-tray or close-tray impression technique during clinical and laboratory ph...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2009.00241.x
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Immediate/early loading protocols are becoming frequently used in implant dentistry, but the prerequisites for achieving good results and the limitations of such protocols are not fully known. Moreover, the terminology used in immediate/early loading is still confusing. PURPOSE:The purpose of this article i...
journal_title:Clinical implant dentistry and related research
pub_type: 共识发展会议,杂志文章,评审
doi:10.1111/j.1708-8208.2003.tb00183.x
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Full-arch immediate function protocols such as the All-on-4 concept need long-term validation. PURPOSE:To report the 5-13 year outcomes of the All-on-4 treatment concept for the rehabilitation of the edentulous maxilla. MATERIALS AND METHODS:This retrospective case series study involved 1072 patients (4288...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12771
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:Reactive oxygen species contribute to periodontal tissue homeostasis under control of anti-oxidative responses. Disruption in this balance induces severe inflammation and extended tissue degradation. PURPOSE:Aim of this study was to identify the expression levels of nuclear factor, erythroid 2 like 2 (NFE2L...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12619
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Elicitation of the relationship of periodontopathogens and pro-inflammatory cytokines to bone resorption and formation is significant to a growing body of research known as osteoimmunology. It is essential that clinically healthy peri-implant and periodontal sites are studied to contribute comparison data fo...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2007.00076.x
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Before early functional loading of unsplinted implants with mandibular overdentures can become widespread, more clinical studies are needed to investigate the success of the approach. PURPOSE:To evaluate the success rates of two types of roughened titanium surface implants with early 2-week functional loadi...
journal_title:Clinical implant dentistry and related research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1708-8208.2003.tb00196.x
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:High failure rates have been presented for implants placed in grafted bone. The bone graft-implant interface constitutes a most complex healing situation, where the time scale for osseointegration and development of implant stability currently is not known. PURPOSE:The aim of the study was to measure the st...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.1999.tb00094.x
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Mesenchymal stem cell (MSC) treatment in conjunction with bone graft materials or space filler can be an alternative to autogenous bone grafts in the treatment of peri-implant bone defects. PURPOSE:To evaluate the success of bone regeneration capacity of adipose-derived and bone marrow-derived MSCs for the ...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12378
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:Straumann® BoneCeramic™ is a synthetic biphasic calcium phosphate (BCP) aimed for sinus floor augmentation. Long-term follow-up of implants placed in BCP after sinus augmentation is still missing. PURPOSE:The primary aim of the study was to compare survival rates and marginal bone loss of Straumann SLActive...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12374
更新日期:2016-10-01 00:00:00
abstract:BACKGROUND:A moderately rough surface implant (TiUnite, Nobel Biocare AB, Göteborg, Sweden) was introduced in 2000. Laboratory studies and some clinical studies have demonstrated excellent bone response in the early healing phase. PURPOSE:The aim of this prospective multicenter study was to follow a large number of co...
journal_title:Clinical implant dentistry and related research
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1111/j.1708-8208.2005.tb00077.x
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Maxillary sinus floor elevation surgery is widely used as a preimplantology method to permit implant insertion. Nevertheless, very few data are available about long-term stability of dental implants inserted in grafted sites. PURPOSE:The aims of the present study were to evaluate the evolution of resonance ...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2008.00113.x
更新日期:2009-09-01 00:00:00
abstract:BACKGROUND:Implant restorations became the first choice for single-tooth replacement today. PURPOSE:The prospective clinical trial aims to investigate computer-aided-design (CAD)/computer-aided-manufacturing (CAM)-processed implant crowns after 5 years of loading. MATERIALS AND METHODS:Twenty patients were included f...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章,随机对照试验
doi:10.1111/cid.12681
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Autogenous bone grafts obtained by different harvesting techniques behave differently during the process of graft consolidation; the underlying reasons are however not fully understood. One theory is that harvesting techniques have an impact on the number and activity of the transplanted cells which contribu...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2012.00440.x
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:Peri-implant mucositis is very common and, when left untreated, can progress to the more serious condition of peri-implantitis. Therefore, early diagnosis, adequate treatment and, in particular, adherence to a peri-implant supportive therapy are extremely important for the management of peri-implant mucositi...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/cid.12833
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:The original Brånemark protocol for dental implant treatment was based on submerged healing prior to loading. However, immediate loading has been reported possible with high success rates for various indications, provided that good bone quality and quantity are present. In many of these studies, machined-sur...
journal_title:Clinical implant dentistry and related research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1708-8208.2003.tb00015.x
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:The aim of this study was to present the clinical outcomes of the immediate loading of two bar-splinted implants retaining a mandibular overdenture. MATERIALS AND METHODS:In a clinical trial, 124 edentulous patients were treated according to a new treatment concept, which involves the immediate loading of two ...
journal_title:Clinical implant dentistry and related research
pub_type: 临床试验,杂志文章
doi:10.1111/j.1708-8208.2009.00210.x
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Discrimination between ongoing and solved research questions may help to distinguish established dogmas from evidence-based implant dentistry. PURPOSE:The purpose of this study was to investigate topics of interest in the field of oral implant science and evolving thematic trends in clinical studies during ...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章,评审
doi:10.1111/cid.12371
更新日期:2016-08-01 00:00:00
abstract:PURPOSE:The aim of this retrospective clinical study was to evaluate the clinical outcome of fixed implant-supported complete prostheses on Astra or Brånemark implants when using either conventional cast frameworks or frameworks produced according to the Cresco Ti Precision method (Cresco Ti Systems Sàrl., Lausanne, Sw...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2005.tb00064.x
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To investigate the effectiveness of adding leukocyte and platelet-rich fibrin (L-PRF) to deproteinized bovine bone mineral (DBBM) for early implant placement after maxillary sinus augmentation. MATERIALS AND METHODS:Twelve patients requiring two-stage bilateral maxillary sinus augmentation were enrolled to the...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章,随机对照试验
doi:10.1111/cid.12713
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Rigid temporization has been recognized to have a significant impact on the peri-implant tissue response in immediate implant loading since it reduces the mechanical stress exerted on each implant. PURPOSE:A successful protocol for immediate loading of multiple implants depends on an adequate fixation and i...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2006.00011.x
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to compare survival rates and marginal bone resorption of the Lifecore (LC) Restore Implant System with the benchmark Nobel Biocare (NB) MK II Implant System. MATERIALS AND METHODS:All implants were inserted by the same surgeon and all radiological analyses were performed by the s...
journal_title:Clinical implant dentistry and related research
pub_type: 杂志文章
doi:10.1111/j.1708-8208.2008.00115.x
更新日期:2009-09-01 00:00:00