Enhancing genetic disease control by selecting for lower host infectivity and susceptibility.

abstract：:Here I develop the idea that ubiquitous harmful genome-wide mutation with local differentiation favors dispersal, even though migration reduces average fitness. Historical contingency of the mutational process means that demes (sub-populations) differentiate from one another. Deleterious or lethal partially recessive ...

journal_title：Heredity

authors： Morgan MT

更新日期：2002-10-01 00:00:00

abstract：:Galton's ancestral law states that the two parent contribute between them on average one-half of the total heritage of the offspring, the four grandparents one-quarter, and so on. He interpreted this law both as a representation of the separate contributions of each ancestor to the heritage of the offspring and as a m...

journal_title：Heredity

authors： Bulmer M

更新日期：1998-11-01 00:00:00

abstract：:WOLBACHIA are maternally inherited bacteria, which are very common in arthropods and nematodes. Wolbachia infection may affect host reproduction through feminisation, parthenogenesis, male-killing, cytoplasmic incompatibility and increased fecundity. Previous studies showing discrepancies between the phylogenies of Wo...

journal_title：Heredity

authors： Reuter M,Pedersen JS,Keller L

更新日期：2005-03-01 00:00:00

abstract：:The sibling species Anopheles atroparvus and Anopheles labranchiae are cytogenetically almost indistinguishable. The chromosome complement (2n = 6) consists of two pairs of autosomes and two heteromorphic sex chromosomes with largely homologous heterochromatic long arms. Treatment of chromosome preparations with the r...

journal_title：Heredity

authors： Marchi A,Mezzanotte R

更新日期：1990-08-01 00:00:00

abstract：:In early 1992, the European bumblebee, Bombus terrestris, was first seen in Tasmania and currently has spread to most of the island. Here, we report on the genetic structure, using micro-satellites, of the invading population from samples collected in the years 1998-2000, a few years after the first sighting of the sp...

journal_title：Heredity

authors： Schmid-Hempel P,Schmid-Hempel R,Brunner PC,Seeman OD,Allen GR

更新日期：2007-10-01 00:00:00

abstract：:Echinoderms represent a researchable subset of a dynamic larval evolutionary cosmos. Evolution of echinoderm larvae has taken place over widely varying time scales from the origins of larvae of living classes in the early Palaeozoic, approximately 500 million years ago, to recent, rapid and large-scale changes that ha...

journal_title：Heredity

authors： Raff RA,Byrne M

更新日期：2006-09-01 00:00:00

abstract：:Despite the crucial role of cyanobacteria in various ecosystems, little is known about their evolutionary histories, especially microevolutionary dynamics, because of the lack of knowledge regarding their mutation rates. Here we directly estimated cyanobacterial mutation rates based on ancient DNA analyses of ice core...

journal_title：Heredity

authors： Segawa T,Takeuchi N,Fujita K,Aizen VB,Willerslev E,Yonezawa T

更新日期：2018-06-01 00:00:00

abstract：:Correlated multiple testing is widely performed in genetic research, particularly in multilocus analyses of complex diseases. Failure to control appropriately for the effect of multiple testing will either result in a flood of false-positive claims or in true hits being overlooked. Cheverud proposed the idea of adjust...

journal_title：Heredity

authors： Li J,Ji L

更新日期：2005-09-01 00:00:00

abstract：:We investigated intraspecific and interspecific patterns of paternity in Tribolium castaneum, the flour beetle, by mating females either to pairs of conspecific males or to one conspecific and one heterospecific male of the closely related species, T. freemani. Females of both species store sperm in the spermatheca af...

journal_title：Heredity

authors： Robinson T,Johnson NA,Wade MJ

更新日期：1994-08-01 00:00:00

abstract：:Stable hybrid zones in which ecologically divergent taxa give rise to a range of recombinants are natural laboratories in which the genetic basis of adaptation and reproductive isolation can be unraveled. One such hybrid zone is formed by the fire-bellied toads Bombina bombina and B. variegata (Anura: Discoglossidae)....

journal_title：Heredity

authors： Nürnberger B,Hofman S,Förg-Brey B,Praetzel G,Maclean A,Szymura JM,Abbott CM,Barton NH

更新日期：2003-08-01 00:00:00

abstract：:We present an approach for quantitative trait locus (QTL) mapping, termed as 'lineage-specific QTL mapping', for inferring allelic changes of QTL evolution along with branches in a phylogeny. We describe and analyze the simplest case: by adding a third taxon into the normal procedure of QTL mapping between pairs of ta...

journal_title：Heredity

authors： Chen C,Ritland K

更新日期：2013-08-01 00:00:00

abstract：:Blue mussels of the genus Mytilus have an unusual mode of mitochondrial DNA inheritance termed doubly uniparental inheritance (DUI). Females are homoplasmic for the F mitotype which is inherited maternally, whereas males are heteroplasmic for this and the paternally inherited M mitotype. In areas where species distrib...

journal_title：Heredity

authors： Wood AR,Turner G,Skibinski DO,Beaumont AR

更新日期：2003-10-01 00:00:00

abstract：:P elements, both complete and incomplete, contain a left and right end, normally depicted as pointing away from each other. Here, we examine the properties of P elements that may be described as 're-arranged elements' or 'inside-out elements', containing inverted ends. Two such structures exist, having either ends poi...

journal_title：Heredity

authors： Liang X,Sved JA

更新日期：2009-04-01 00:00:00

abstract：:We conducted controlled crosses in populations of the long-lived clonal shrub, Vaccinium angustifolium (lowbush blueberry) to estimate inbreeding depression and mutation parameters associated with somatic deleterious mutation. Inbreeding depression level was high, with many plants failing to set fruit after self-polli...

journal_title：Heredity

authors： Bobiwash K,Schultz ST,Schoen DJ

更新日期：2013-10-01 00:00:00

abstract：:Knowledge of the degree of temporal stability of population genetic structure and composition is important for understanding microevolutionary processes and addressing issues of human impact of natural populations. We know little about how representative single samples in time are to reflect population genetic constit...

journal_title：Heredity

authors： Charlier J,Laikre L,Ryman N

更新日期：2012-10-01 00:00:00

abstract：:The pattern of colonization of a forest site by the ectomycorrhizal basidiomycete fungus Hebeloma cylindrosporum Romagnesi was followed from 1993 until 1997. Fruit-bodies of this tetrapolar heterothallic species were mapped, collected and propagated as pure mycelial cultures. Isolates were analysed for their mating-ty...

journal_title：Heredity

authors： Gryta H,Debaud JC,Marmeisse R

更新日期：2000-03-01 00:00:00

abstract：:Invasive species are believed to spread through a process of stratified dispersal consisting of short-distance diffusive spread around established foci and human mediated long-distance jumps. Brazilian peppertree (Schinus terebinthifolius), native to South America, was introduced twice as an ornamental plant into Flor...

journal_title：Heredity

authors： Williams DA,Muchugu E,Overholt WA,Cuda JP

更新日期：2007-05-01 00:00:00

abstract：:Principal components analysis of genetic data is used to avoid inflation in type I error rates in association testing due to population stratification by covariate adjustment using the top eigenvectors and to estimate cluster or group membership independent of self-reported or ethnic identities. Eigendecomposition tra...

journal_title：Heredity

authors： Shriner D

更新日期：2011-10-01 00:00:00

abstract：:The study of local adaptation is rendered difficult by many evolutionary confounding phenomena (for example, genetic drift and demographic history). When complex traits are involved in local adaptation, phenomena such as phenotypic plasticity further hamper evolutionary biologists to study the complex relationships be...

journal_title：Heredity

authors： de Villemereuil P,Gaggiotti OE,Mouterde M,Till-Bottraud I

更新日期：2016-03-01 00:00:00

abstract：:Pinewood nematode (Bursaphelenchus xylophilus) is an invasive species that causes a destructive forest disease-pine wilt disease. This disease has been prevalent in some countries in Asia since the 1970s. An amplified fragment length polymorphism survey was used to compare the genetic variation of native and invasive ...

journal_title：Heredity

authors： Cheng XY,Cheng FX,Xu RM,Xie BY

更新日期：2008-04-01 00:00:00

abstract：:Haplodiploidy is one of the most widespread mechanisms of sex determination in animals. In many Hymenoptera, including all hitherto investigated social species, diploid individuals, which are heterozygous at the sex locus, develop as females, whereas haploid, hemizygous individuals develop as males (single-locus compl...

journal_title：Heredity

authors： Schrempf A,Aron S,Heinze J

更新日期：2006-07-01 00:00:00

abstract：:How does genetic diversity within populations of plants develop during primary succession on alpine glacier forelands? Theory predicts that pioneer populations are characterized by low genetic diversity due to founder effects and that genetic diversity increases within populations as they mature and recurrent gene flo...

journal_title：Heredity

authors： Raffl C,Holderegger R,Parson W,Erschbamer B

更新日期：2008-05-01 00:00:00

abstract：:Forty-two homozygous lines each isoallelic for the Esterase 6 (Est-6) locus were extracted from a natural population of Drosophila melanogaster. Homogenates of 4-5 day old virgin adults of each sex from several replicate cultures of each line were assayed for EST6 activity. Depending on the line, males had from three ...

journal_title：Heredity

authors： Game AY,Oakeshott JG

更新日期：1989-02-01 00:00:00

abstract：:The sequences of ITS1 of the internal transcribed spacer regions of nuclear ribosomal DNA from 11 species or subspecies in four sections of the genus Beta were compared. Phylogeny of these wild beet taxa was inferred from the sequence data using phenetic and phylogenetic analyses. Multiple accessions from the same 11 ...

journal_title：Heredity

authors： Shen Y,Ford-Lloyd BV,Newbury HJ

更新日期：1998-05-01 00:00:00

abstract：:Distinguishing genetically differentiated populations within hybrid zones and determining the mechanisms by which introgression occurs are crucial for setting effective conservation policy. Extensive hybridization among grey wolves (Canis lupus), eastern wolves (C. lycaon) and coyotes (C. latrans) in eastern North Ame...

journal_title：Heredity

authors： Rutledge LY,Garroway CJ,Loveless KM,Patterson BR

更新日期：2010-12-01 00:00:00

abstract：:Eukaryotic genomes frequently acquire new protein-coding genes which may significantly impact an organism's fitness. Novel genes can be created, for example, by duplication of large genomic regions or de novo, from previously non-coding DNA. Either way, creation of a novel transcript is an essential early step during ...

journal_title：Heredity

authors： Schmitz JF,Chain FJJ,Bornberg-Bauer E

更新日期：2020-08-01 00:00:00

abstract：:Many populations of the buprestid leaf-mining beetle, Brachys tessellatus, from central South Carolina, USA, show highly skewed sex ratios, ranging from 1.3 to 6.0 females per male. We have identified a Rickettsia bacterium that is associated with sex ratio distortion (SRD) and selective killing of male embryos in B. ...

journal_title：Heredity

authors： Lawson ET,Mousseau TA,Klaper R,Hunter MD,Werren JH

更新日期：2001-04-01 00:00:00

abstract：:The genetic differentiation of populations is usually studied by using the equilibrium theory of Wright's infinite island model. In practice, however, populations are not always in equilibrium, and the number of subpopulations is often very small. To get some insight into the dynamics of genetic differentiation of the...

journal_title：Heredity

authors： Varvio SL,Chakraborty R,Nei M

更新日期：1986-10-01 00:00:00

abstract：:To improve the efficiency of gynogenetic induction, the effects of UV light and thermal shock on gametes were investigated in the sea bass. Exposure of sperm to UV light (>/=15 000 erg mm-2) reduced the amount of motile spermatozoa, without affecting the duration of motility in the spermatozoa that remained motile. Th...

journal_title：Heredity

authors： Felip A,Piferrer F,Carrillo M,Zanuy S

更新日期：1999-10-01 00:00:00

abstract：:Connectivity is widely recognized as an important component in developing effective management and conservation strategies. Although managers are generally most interested in demographic, rather than genetic connectivity, new analytic approaches are able to provide estimates of both demographic and genetic connectivit...

journal_title：Heredity

authors： Thomas L,Bell JJ

更新日期：2013-10-01 00:00:00