Abstract：
AIM:The aim of this study was to assess the efficacy of propranolol treatment in multifocal and diffuse infantile hepatic haemangioma (IHH). METHODS:A retrospective study of symptomatic or potentially symptomatic IHH was performed in our hospital between 2011 and 2016. RESULTS:Thirteen patients were identified: 2 patients had diffuse lesions, and 11 patients had multifocal lesions, including 2 patients who had combined lesions that shared features of both multifocal and diffuse lesion patterns. Eleven (84.6%) patients had cutaneous infantile haemangioma. Hepatomegaly was the predominant clinical presentation. Hypothyroidism was identified in three patients, including one patient who had documented congestive heart failure (CHF). The median age at diagnosis and the median duration of treatment were 2.0 months (range 1.2-26.0) and 24.0 months (range 4.0-30.0). The median duration of follow-up was 30.0 months (range 3.0-48.0). For patients with hypothyroidism, the thyroid hormone level was normal after 4 weeks of propranolol and levothyroxine treatment. All but one patient responded well to propranolol treatment. The patient who failed to respond to treatment died of CHF and abdominal compartment syndrome induced by hepatomegaly. No significant side effects of propranolol were observed during follow-up. CONCLUSIONS:Most multifocal and diffuse IHH respond well to propranolol. However, progressive cases may be fatal despite aggressive treatments. Our data suggest that propranolol may be considered the first-line treatment for multifocal and diffuse IHH due to its efficacy.
journal_name
J Paediatr Child Healthjournal_title
Journal of paediatrics and child healthauthors
Yang K,Peng S,Chen L,Chen S,Ji Ydoi
10.1111/jpc.14375subject
Has Abstractpub_date
2019-10-01 00:00:00pages
1194-1200issue
10eissn
1034-4810issn
1440-1754journal_volume
55pub_type
杂志文章abstract：OBJECTIVE:To define the bowel habits of healthy Australian children aged up to 2 years. METHODOLOGY:One hundred and forty children were recruited in six age categories with a minimum of 20 children per category. Data on bowel habit was recorded by parents daily for 1 week. RESULTS:Stool frequency decreased with age. ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1996.tb00963.x
更新日期：1996-12-01 00:00:00
abstract：:The recently released World Health Organization growth charts are methodologically robust, as well as clinically useful tools for monitoring the growth of children. They have been endorsed by premier organisations such as the Royal College of Paediatrics and Child Health (UK), Canadian Pediatric Society, Australian Br...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章,评审
doi：10.1111/j.1440-1754.2011.02214.x
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVES:The aims of our study were to review the Royal Children's Hospital cohort of children having thyroidectomy for thyroid nodules over the last 8 years and to report the changing pattern of thyroid cancer seen in our institution over that time. METHODS:We undertook a retrospective case-note review of all patie...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00724.x
更新日期：2005-11-01 00:00:00
abstract：:The disorder of multiple cranial nerve palsies without spinal cord involvement is referred to as polyneuritis cranialis (PC) and is rare. It is thought to be an acute post-infective polyneuropathy or a variant of Guillain-Barré syndrome. Electrophysiological evidence of demyelination has been reported, but no radiolog...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2003.00074.x
更新日期：2003-01-01 00:00:00
abstract：AIM:To evaluate the intake of a soy protein-based supplement (SPS) and its effects on the sexual maturation and nutritional status of prepubertal children who consumed it for a year. METHODS:Healthy children (n = 51) were recruited and randomly assigned to consume the lunch fruit juice with (n = 29) or without (n = 22...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.13934
更新日期：2018-09-01 00:00:00
abstract：:Crigler-Najjar syndrome type 1 (CNS1) is characterized by a severe unconjugated hyperbilirubinemia from birth. Intensive blue-light phototherapy is the standard method for management; however, it imposes severe restrictions on the child and their family's lifestyle. We describe here the use of a novel sit-up photother...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00642.x
更新日期：2005-07-01 00:00:00
abstract：AIM:Based on our experience with acute idiopathic scrotal oedema (AISO) and observations of the incidence of intestinal worm infestation (IWI), we decided to test the hypothesis that IWI occurs more frequently among children with AISO than it does in the general population. METHODS:A retrospective questionnaire-based ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2011.02182.x
更新日期：2012-01-01 00:00:00
abstract：BACKGROUND:Acute flaccid paralysis (AFP) is the most common clinical presentation of acute poliovirus infection, occurring in 0.1-1% of infected cases. AFP surveillance has been used world-wide to monitor the control and eradication of circulating wild poliovirus. This study aims to review the significance of all enter...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2006.00875.x
更新日期：2006-06-01 00:00:00
abstract：AIM:To examine the differences in return to work time after childbirth; the differences in income; and the differences in out of pocket health-care costs between mothers who had a preterm birth and mothers who delivered a full term baby in Australia. METHODS:Using administrative data, the length of time and 'risk' of ...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.15278
更新日期：2021-01-10 00:00:00
abstract：AIM:Paediatric haematopoietic stem cell donors undergo non-therapeutic procedures and endure known and unknown physical and psychosocial risks for the benefit of a family member. One ethical concern is the risk that they may be pressured by parents or health professionals to act as a donor. This paper adds to what is k...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12934
更新日期：2015-12-01 00:00:00
abstract：AIM:Footprints have long been used as proxy measures of foot morphology, yet there is little consensus regarding footprints versus measures of foot posture, which address foot anatomy directly. Foot posture in children can be a confusing clinical presentation, with previous studies both supporting and refuting the rela...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14558
更新日期：2020-02-01 00:00:00
abstract：:A child with psychotic symptoms and attention-deficit hyperactivity disorder who developed extrapyramidal symptoms while on a combination of risperidone, methylphenidate, sertraline, tropisetron and ketorolac is described herein. The extrapyramidal symptoms resolved with the administration of benztropine, an anticholi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00719.x
更新日期：2002-02-01 00:00:00
abstract：AIM:The relationship between obstructive sleep apnoea (OSA) and poorer neurobehavioural outcomes in school-age children is well established, but the relationship in obese children and adolescents, in whom OSA is more common, is not so well established. We aimed to investigate this relationship in 10-18-year-olds. METH...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12390
更新日期：2014-01-01 00:00:00
abstract：AIM:Chest compression depth (CCD) decreases significantly when performing one-handed chest compression (OHCC). We modified OHCC posture to increase CCD as follows: first, the axis of the compression hand was adjusted to the compression area; second, the opposite hand was wrapped around the elbow of the compression arm....
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14422
更新日期：2019-11-01 00:00:00
abstract：:The clinical course of a term neonate (birthweight 3.14 kg) who developed thrombosis of the left common and internal iliac veins on day 21 following recovery from Streptococcus mitis septicemia, with shock diagnosed on day 13, is reported. Subcutaneous low molecular weight heparin (LMWH) was commenced (1.5 mg/kg 12 ho...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00052.x
更新日期：2002-12-01 00:00:00
abstract：OBJECTIVES:To document whether medically stable infants can be transferred safely from incubators to unheated, open cots at 1500 g. METHODS:Four cohorts were recruited in a stepwise observational trial of transfer from incubators to unheated, open cots. We aimed to transfer the first 15 infants into cots on reaching a...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2005.00754.x
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:To identify barriers to the use of trained interpreters in emergency department (ED) paediatric consultations. METHODS:A cross-sectional survey of non-English-speaking-background (NESB) carers who presented a child aged 14 years or less to the Fairfield Hospital ED during a 3-month period was undertaken usin...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2003.00135.x
更新日期：2003-05-01 00:00:00
abstract：AIM:To investigate parental attitudes to cystic fibrosis (CF) carrier detection of their infant by newborn screening (NBS). METHODS:Data were collected from a postal questionnaire sent to parents of infants identified as CF carriers by NBS in 1996-1997 (inclusive) and 2001 in Victoria, Australia (n = 66). RESULTS:Alm...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2006.00917.x
更新日期：2006-09-01 00:00:00
abstract：AIM:This study aims to examine the influence of formula milk promotion via the media from Thailand to Lao People's Democratic Republic (PDR), where a cultural and linguistic proximity are shared. METHODS:A cross-sectional study was conducted through a structured questionnaire survey and focus group discussion (FGD) wi...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12391
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To determine the common features of small bowel injury (SBI) in childhood and the consequences of delayed diagnosis. METHODOLOGY:A retrospective case review was performed of children with traumatic SBI between January 1988 and November 1999. RESULTS:Twenty-eight patients were identified with SBI. Road traum...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2000.00502.x
更新日期：2000-06-01 00:00:00
abstract：:We discuss a recently resettled African refugee child with acute schistosomiasis, who presented with fever, hepatosplenomegaly and marked eosinophilia. We outline the differential diagnoses of eosinophilia in the recently resettled refugee and returned traveller and outline the epidemiology and clinical spectrum of sc...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2012.02523.x
更新日期：2012-10-01 00:00:00
abstract：OBJECTIVE:To describe the obstetric and perinatal factors, in particular the method of delivery, associated with development of a subgaleal haematoma (SGH) and to determine the outcome of survivors with this type of birth trauma. METHODOLOGY:Perinatal and obstetric data were retrospectively reviewed for 37 infants adm...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1996.tb01559.x
更新日期：1996-06-01 00:00:00
abstract：:Many Aboriginal women do not recall their last menstrual period date, so alternative methods of estimating gestational age are necessary for optimal obstetric and neonatal care. In this retrospective review of 605 Aboriginal infants born at the Royal Darwin Hospital, the gestational age was estimated by the Dubowitz m...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.1992.tb02675.x
更新日期：1992-08-01 00:00:00
abstract：:We describe three infants born to mothers with poorly controlled Graves' disease, who developed transient central hypothyroidism in the immediate postnatal period. Suppression of the fetal pituitary-thyroid axis may be due to placental transfer of thyroxine from the hyperthyroid mother. This may persist for months pos...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00741.x
更新日期：2002-04-01 00:00:00
abstract：AIM:To compare adverse medication events (AMEs) reported in children, via the International Statistical Classification of Diseases and Related Health Problems 10th Revision (ICD-10) coding with events reported via other data sources. METHOD:AME reports were retrieved using codes Y40-Y59 and X40-X44 over 6 months. Pati...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12684
更新日期：2014-12-01 00:00:00
abstract：:We present the case of a 16-year-old male who presented reporting a 6-month history of lowered mood, fatigue, anhedonia, disturbed sleep and heightened anxiety. On further questioning he reported restricted eating and weightlifting for at least 1 h on a daily basis. Investigations revealed findings compatible with sec...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.12495
更新日期：2014-09-01 00:00:00
abstract：AIM:Hepatitis A and E are enteric viral diseases that are characteristically found in developing countries. Sero-epidemiological data about both infections showed higher prevalence rates soon after the 1999 earthquakes in Duzce, Turkey. The aim of the present study was to evaluate the data 4 years after the earthquakes...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2007.01248.x
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVES:To evaluate the habits of betel quid use and areca nut chewing among school-aged children in Karachi, Pakistan. Areca nut (betel nut) is chewed by itself, in various scented preparations, and in betel quid (containing betel leaf, areca nut, slaked lime, condiments, sweeteners and sometimes tobacco) in variou...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1046/j.1440-1754.2002.00040.x
更新日期：2002-10-01 00:00:00
abstract：:Congenital rubella syndrome can be associated with disgammaglobulinaemia and autoimmune phenomena in adult and paediatric population. The aim of this article is to present the association between a congenital rubella syndrome with hypogammaglobulinaemia and hyper IgM diagnosed at the age of 8 months and autoimmune man...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/j.1440-1754.2007.01144.x
更新日期：2007-10-01 00:00:00
abstract：:Paediatricians contribute the greatest proportion of prescriptions for psychotropic medication to children between the ages of 3 and 14 years in Australia. Medications indicated for attention-deficit hyperactivity disorder are the most commonly prescribed, followed by antidepressants and antipsychotics. Outside treatm...
journal_title：Journal of paediatrics and child health
pub_type： 杂志文章
doi：10.1111/jpc.14155
更新日期：2018-10-01 00:00:00
