Sexual orientation of 46, XX patients with congenital adrenal hyperplasia: a descriptive review.

Abstract:

BACKGROUND:Congenital adrenal hyperplasia (CAH) consists of a group of diseases characterized by an enzyme deficiency, particularly 21-hydroxylase deficiency. The condition may present in the simple virilizing form or in the salt-wasting form, with varying degrees of genital ambiguity. The non-heterosexual orientation is used in gender studies fields and includes bisexual, homosexual, Lesbians, gays, bissexuals, transgender, intersex, and others. OBJECTIVE:The objective of this study was to evaluate the frequency of non-heterosexual orientation in patients with CAH, in an attempt to identify biological factors possibly associated with this occurrence. METHODS:This was a descriptive review of observational studies on the sexual orientation of patients with CAH published between 1985 and 2016, as listed in PubMed. RESULTS:Various studies have been performed to establish the relationship between CAH and non-heterosexual orientation. Non-heterosexual orientation is more prevalent in patients with more advanced Prader stages and those with the null and I2-splice genotype. CONCLUSION:The prevalence of homosexuality and bisexuality is greater in patients with CAH in relation to the general population.

journal_name

J Pediatr Urol

authors

Gondim R,Teles F,Barroso U Jr

doi

10.1016/j.jpurol.2018.08.004

subject

Has Abstract

pub_date

2018-12-01 00:00:00

pages

486-493

issue

6

eissn

1477-5131

issn

1873-4898

pii

S1477-5131(18)30437-6

journal_volume

14

pub_type

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