Development and validation of a bladder trabeculation grading system in pediatric neurogenic bladder.

Abstract:

:Bladder trabeculation (BT) is commonly noted on cystogram images of patients with neurogenic bladder (NB). BT is associated with a hostile bladder often requiring prompt, more aggressive management. We aimed to define and validate a reliable grading system for BT severity. The proposed grading system will improve clinicians and radiologist's communication and serve as a foundation for future studies in the field of NB. The study was conducted in two phases: 1) Development of a grading system for BT and 2) testing of the proposed grading system for reliability and validity. Agreement between raters was assessed using Cohen's Kappa. Inter-rater reliability and intra-rater reliability was assessed using intra-class correlation coefficients (ICC) and Spearman's p (rho) correlation coefficient. The content of the grading system was assessed for face validity by senior pediatric urology and radiology experts. We observed inter-rater reliability with ICC of 0.998 (95%CI 0.996-0.999, p < 0.001), and a Cohen's Kappa ranging from 0.795 to 1.0, p < 0.001 and Spearman's p (rho) correlation coefficient ranging from 0.910 to 1.0, p < 0.001 between raters on the decided grades of BT. In conclusion, we established a defined grading system for BT severity that has substantial inter/intra-rater reliability and validity. This grading system could be useful for improving clinician and radiologist's communication about the status of a child's bladder wall and serve as a foundation for future studies assessing severity of NB.

journal_name

J Pediatr Urol

authors

Selby B,Hidas G,Chuang KW,Soltani T,Billimek J,Kaplan S,Wehbi E,Khoury A

doi

10.1016/j.jpurol.2020.03.007

subject

Has Abstract

pub_date

2020-06-01 00:00:00

pages

367-370

issue

3

eissn

1477-5131

issn

1873-4898

pii

S1477-5131(20)30060-7

journal_volume

16

pub_type

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