A meta-analysis of safety and efficacy of regorafenib for refractory metastatic colorectal cancer.

abstract：:As detection rates of non-albicans Candida species are increasing, determining their pathogen profiles and antifungal susceptibilities is important for antifungal treatment selection. We identified the antifungal susceptibility patterns and predictive factors for mortality in candidemia.A multicenter retrospective ana...

journal_title：Medicine

authors： Jung IY,Jeong SJ,Kim YK,Kim HY,Song YG,Kim JM,Choi JY

更新日期：2020-03-01 00:00:00

abstract：RATIONALE:The emphysematous prostatic abscess is a rare but potentially life-threatening clinical condition. The early diagnosis is difficult due to nonspecific symptoms. PATIENT CONCERNS:A 72-year-old man with poorly controlled diabetes mellitus was admitted to hospital because of dysuria and acute urine retention. H...

journal_title：Medicine

authors： Li Z,Wen J,Zhang N

更新日期：2020-02-01 00:00:00

abstract：RATIONALE:Pulmonary amyloidosis is a rare respiratory disease characterized by amyloid deposition in the lungs. The clinical manifestations of pulmonary amyloidosis are variable and without specific symptoms. PATIENT CONCERNS:We report a rare case of tracheobronchial amyloidosis to improve our understanding of the dis...

journal_title：Medicine

authors： Peng X,Wang X,Luo D,Zuo W,Yao H,Zhang W

更新日期：2020-06-26 00:00:00

abstract：RATIONALE:Primary pulmonary meningiomas are extremely rare, and only a few cases have been reported in the medical literature. Imaging findings of primary pulmonary meningiomas have been reported even more rarely. PATIENT CONCERNS:We present the case of a 54-year-old male patient with cough and sputum lasting for 20 y...

journal_title：Medicine

authors： Hong S,Jiang J,Zhou F,Liu J

更新日期：2018-01-01 00:00:00

abstract：RATIONALE:Acute fatty liver of pregnancy (AFLP) is extremely hazardous to pregnant woman in the 3rd trimester of pregnancy. AFLP has an insidious onset and nonspecific experimental indicators, which therefore is difficult to be diagnosed. PATIENT CONCERNS:Case 1 was transferred to our hospital for hypertensive disorde...

journal_title：Medicine

authors： Wang L,Gan Q,Du S,Zhao Y,Sun G,Lin Y,Li R

更新日期：2020-07-17 00:00:00

abstract：RATIONALE:Congenital myasthenic syndrome (CMSs) are a group of rare genetic disorders of the neurological junction, which can result in structural or functional weakness. Here, we characterized a case of CMS in order to clarify the diagnosis and expand the understanding of it. The molecular diagnosis had implications f...

journal_title：Medicine

authors： Yang K,Cheng H,Yuan F,Meng L,Yin R,Zhang Y,Wang S,Wang C,Lu Y,Xi J,Lu Q,Chen Y

更新日期：2018-04-01 00:00:00

abstract：BACKGROUND:This systematic review aims to evaluate the efficacy of Gegen Qinlian Decoction (GQD) for ulcerative colitis (UC). METHODS:PubMed, EMBASE, Springer LINK, Cochrane Library, the China National Knowledge Infrastructure, Chongqing Weipu Database for Chinese Technical Periodicals, Wan-fang Database, and Chinese ...

journal_title：Medicine

authors： Fan Y,Yi W,Huang H,Mei Z,Feng Z

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Patients who have tested positive for the human immunodeficiency virus (HIV) and who also experience alcohol use disorder (AUD) symptoms have worse clinical outcomes when compared with those who do not have AUD symptoms. The objective of the present study was to determine the effect of rational emotive healt...

journal_title：Medicine

authors： Omeje JC,Otu MS,Aneke AO,Adikwu VO,Nwaubani OO,Chigbu EF,Onuigbo LN,Udom IE,Aye EN,Akaneme IN,Egeonu DC,Ezema VS,Okpanachi GO,Ohabuenyi AG,Eseadi C,Eze NM

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:The critically ill and surgical patients are at significant risk of delirium, which is associated with a high morbidity and mortality. The association between statin use and the incidence of delirium is still controversial. In this article, we will perform a systematic review and meta-analysis of published s...

journal_title：Medicine

authors： Zeng H,Li Z,He G,Han Y,Fu W,Wen J

更新日期：2018-12-01 00:00:00

abstract：BACKGROUND:The effects of different types of tree nut, peanut, and soy nut consumption on serum C - reactive protein (CRP) are not well established. we aimed to undertake a systematic review and meta-analysis of prospective studies to determine the effect of nut consumption (tree nuts, peanuts, and soy nuts) on serum C...

journal_title：Medicine

authors： Mazidi M,Rezaie P,Ferns GA,Gao HK

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Recent studies have demonstrated that coronary microcirculation dysfunction (CMVD) is closely correlated with adverse clinical outcomes. In this study, quantitative stress myocardial contrast echocardiography (MCE) was used to evaluate the CMVD and to investigate its association with the prognosis of patient...

journal_title：Medicine

authors： Yang N,Su YF,Li WW,Wang SS,Zhao CQ,Wang BY,Liu H,Guo M,Han W

更新日期：2019-07-01 00:00:00

abstract：RATIONALE:Vortioxetine is a new multimodal antidepressant approved by the Food and Drug Administration for the treatment of Major Depressive Disorder and recently introduced in Europe. While antidepressant properties of vortioxetine and its tolerability have been demonstrated by preclinical and clinical studies data on...

journal_title：Medicine

authors： Mazza MG,Rossetti A,Botti ER,Clerici M

更新日期：2018-06-01 00:00:00

abstract：:Unplanned reoperations have not been studied extensively in pediatric patients, especially concerning risk factors. We aim to estimate the rate of unplanned reoperations and to determine the associated factors in pediatric general surgical specialties.This analysis included a retrospective case-control study of unplan...

journal_title：Medicine

authors： Li A,Zhu H,Zhou H,Liu J,Deng Y,Liu Q,Guo C

更新日期：2020-05-01 00:00:00

abstract：RATIONALE:Ossifying fibroma is benign fibro-osseous neoplasm. The authors report a case of ossifying fibroma in the mandibular angle suspected as metastasis of clear cell renal cell carcinoma. PATIENT CONCERNS:A 74-year-old man presented to the primary hospital complaining of frequent urination. A tumor in the left ki...

journal_title：Medicine

authors： Matsuda S,Yoshimura H,Yoshida H,Taga M,Imamura Y,Kiyoshima T,Sano K

更新日期：2019-08-01 00:00:00

abstract：RATIONALE:Hepatoblastoma is a rare malignancy. Approximately 100 cases are diagnosed yearly in the United States. The highest incidence occurs in infants and in children younger than 5 years. Cases involving patients older than 5 years are very rare. We describe the case of a patient who was diagnosed with hepatoblasto...

journal_title：Medicine

authors： Pateva IB,Egler RA,Stearns DS

更新日期：2017-01-01 00:00:00

abstract：:The aim of this study was to study the ability of the genotype to predict impairment and disability in hospitalized ischemic stroke (IS) patients after hospital discharge and 6 months after the onset of stroke symptoms.A total of 786 patients with a first IS were enrolled. Apolipoprotein E (ApoE) polymorphism was exam...

journal_title：Medicine

authors： Zhang Y,Liu S,Yue W,Shi Z,Guan Y,Li M,Ji Y,Li X

更新日期：2017-12-01 00:00:00

abstract：:To date, there is no clear agreement regarding which is the best method to detect a connective tissue disease (CTD) during the initial diagnosis of interstitial lung diseases (ILD). The aim of our study was to explore the impact of a systematic diagnostic strategy to detect CTD-associated ILD (CTD-ILD) in clinical pra...

journal_title：Medicine

authors： Hernandez-Gonzalez F,Prieto-González S,Brito-Zeron P,Cuerpo S,Sanchez M,Ramirez J,Agustí C,Lucena CM,Paradela M,Grafia I,Espinosa G,Sellares J

更新日期：2020-01-01 00:00:00

abstract：:Pelvic inflammatory disease (PID) has been investigated in Western countries and identified to be associated with chronic pelvic pain and inflammation. Bladder pain syndrome/interstitial cystitis (BPS/IC) is a complex syndrome that is significantly more prevalent in women than in men. Chronic pelvic pain is a main sym...

journal_title：Medicine

authors： Chung SD,Chang CH,Hung PH,Chung CJ,Muo CH,Huang CY

更新日期：2015-11-01 00:00:00

abstract：RATIONALE:We report on a patient with injury of the cortico-ponto-cerebellar tract (CPCT) following mild traumatic brain injury (TBI), diagnosed by diffusion tensor tractography (DTT). PATIENT CONCERNS:A 53-year-old female patient was injured in a car crash. While under treatment at a local medical center for headache...

journal_title：Medicine

authors： Jang SH,Kwon HG

更新日期：2017-12-01 00:00:00

abstract：:Based on the source of the embolus, septic pulmonary embolism (SPE) can be classified as cardiac, peripheral endogenous, or exogenous. Cardiac SPEs are the most common.We conducted a retrospective analysis of 20 patients with cardiac SPE hospitalized between 1991 and 2013 at a Chinese tertiary referral hospital.The st...

journal_title：Medicine

authors： Song XY,Li S,Cao J,Xu K,Huang H,Xu ZJ

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND:Flavopiridol a semisynthetic flavone that inhibits cyclin-dependent kinases (CDKs) and has growth-inhibitory activity and induces a blockade of cell-cycle progression at G1-phase and apoptosis in numerous human tumor cell lines and is currently under investigation in phase II clinical trials. Cancer stem cel...

journal_title：Medicine

authors： Bozok Cetintas V,Acikgoz E,Yigitturk G,Demir K,Oktem G,Tezcanli Kaymaz B,Oltulu F,Aktug H

更新日期：2016-10-01 00:00:00

abstract：INTRODUCTION:Acute hydrocephalus is a common complication of spontaneous or traumatic intracranial bleeding with extensive subarachnoid hemorrhage (SAH) or ventricular extension. However, it has never been reported to be secondary to pneumocephalus. PATIENT CONCERNS:A 32-year-old man was admitted following a motorcycl...

journal_title：Medicine

authors： Li G,Wang G,Luan T,Hou K,Yu J

更新日期：2020-01-01 00:00:00

abstract：:In this study, we evaluate the efficacy of short-course radiotherapy (SCRT) versus long-course radiotherapy (LCRT) in the treatment of metastatic spinal cord compression (MSCC).PubMed, EMBASE, and Web of Science were searched up to April 2015. Relevant data were extracted based on inclusion and exclusion criteria. Met...

journal_title：Medicine

authors： Qu S,Meng HL,Liang ZG,Zhu XD,Li L,Chen LX,Zhou ZR

更新日期：2015-10-01 00:00:00

abstract：:Lung ultrasound (LU) is increasingly used to assess pleural and lung disease in intensive care unit (ICU) and emergency unit at the bedside. We assessed the performance of bedside chest radiograph (CR) and LU during severe acute chest syndrome (ACS), using computed tomography (CT) as the reference standard. We prospec...

journal_title：Medicine

authors： Razazi K,Deux JF,de Prost N,Boissier F,Cuquemelle E,Galactéros F,Rahmouni A,Maître B,Brun-Buisson C,Mekontso Dessap A

更新日期：2016-02-01 00:00:00

abstract：:To summarize the clinical features of eyeball rupture with or without orbital fracture and explore the differences between them.In all, 197 patients were observed, and the following data were recorded: sex, age, time of injury, place of injury, cause of trauma, zone of eye injury, intraocular content prolapse, surgica...

journal_title：Medicine

authors： Chen X,Yao Y,Wang F,Liu T,Zhao X

更新日期：2017-06-01 00:00:00

abstract：:Xiakemycin A (XKA), a new antibiotic in the pyranonaphthoquinone family, shows antitumor activity. However, the type of cell death induced by XKA remains elusive. In this study, we aim to investigate the type of death induced by XKA in hepatic cancer.The apoptotic features, such as chromatic agglutination, reactive ox...

journal_title：Medicine

authors： Chen C,Han Z,Yang M,Jiang Z,Ou X

更新日期：2020-04-01 00:00:00

abstract：OBJECTIVE:The aim of present study is to quantitatively evaluate the association between different interventions and abstinence rates based on network meta-analysis. METHOD:Following PRISMA guidelines, randomized clinical trials that compared different alcoholic interventions for alcohol use disorders associated with ...

journal_title：Medicine

authors： Gao J,Cao J,Guo T,Xiao Y

更新日期：2018-12-01 00:00:00

abstract：RATIONALE:Alveolar soft part sarcoma (ASPS) is a rare, malignant neoplasm, which mostly occurs in the upper and lower extremities. This article presents an unusual case of ASPS involving the penis of a 3-year-old boy. To our knowledge, this is the first case of ASPS in the penis of a child. PATIENT CONCERNS:The patien...

journal_title：Medicine

authors： Qiu L,Li Y,Ali SI,Xie M

更新日期：2017-11-01 00:00:00

abstract：:This study aimed to investigate the correlation of microRNA (miR)-206, vascular endothelial growth factor (VEGF) and miR-206/VEGF axis at different gestational ages with fetal growth retardation (FGR) risk in pregnancies.Eight hundred twenty pregnancies were consecutively recruited and their plasma samples were collec...

journal_title：Medicine

authors： Li Y,Liu J

更新日期：2020-02-01 00:00:00

abstract：BACKGROUND:The small renal masses (SRMs) were defined that the diameter of renal masses measured by enhanced image was ≤4 cm. The diagnostic accuracy of contrast-enhanced ultrasound (CEUS) for SRMs is apparently variable among previous studies. Hence, this study will evaluate the diagnostic accuracy of CEUS in the iden...

journal_title：Medicine

authors： Wu JF,Wu C,Wang YL,Wang ZP

更新日期：2020-07-17 00:00:00