Abstract:
:
journal_name
Drug Safjournal_title
Drug safetyauthors
Simoons M,Seldenrijk A,Mulder H,van Roon E,Bakker R,Ruhé Hdoi
10.1007/s40264-018-0716-5subject
pub_date
2018-12-01 00:00:00pages
1417-1418issue
12eissn
0114-5916issn
1179-1942pii
10.1007/s40264-018-0716-5journal_volume
41pub_type
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DRUG SAFETY文献大全abstract:BACKGROUND:At time of approval, knowledge of the full benefit risk of any drug is limited, in particular with regards to safety. Post-approval surveillance of potential drug safety concerns is recognized as an important task of regulatory agencies. For innovative, often first-in-class drugs, safety knowledge at time of...
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更新日期:2019-09-01 00:00:00
abstract::Drugs used in the treatment of peptic ulcer disease may interact with the renal system in a variety of ways. Since many agents are eliminated by renal excretion, clearance of these agents may be reduced and half-life extended in the presence of renal insufficiency. The histamine H2-receptor antagonists may interfere w...
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doi:10.2165/00002018-199207040-00004
更新日期:1992-07-01 00:00:00
abstract::Although inhaled and intranasal corticosteroids are first-line therapy for asthma and allergic rhinitis, there has recently been an increasing awareness of their propensity to produce systemic adverse effects. The availability of more potent and lipophilic corticosteroids and new chlorofluorocarbon (CFC)-free formulat...
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更新日期:2000-07-01 00:00:00
abstract::Many drug products contain excipients which perform important functions in terms of stability, solubility and identification. Excipients should not be considered as inactive ingredients, as they have been associated with a wide range of adverse reactions in some individuals. Monitoring for excipient toxicity is import...
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abstract:BACKGROUND:Automated disproportionality analysis of spontaneous reporting is increasingly used routinely. It can theoretically be influenced by a competition bias for signal detection owing to the presence of reports related to well-established drug-event associations. OBJECTIVE:The aim of the study was to explore the...
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pub_type: 杂志文章,评审
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更新日期:2016-01-01 00:00:00
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journal_title:Drug safety
pub_type: 杂志文章,多中心研究
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更新日期:2012-07-01 00:00:00