Abstract:
BACKGROUND:This randomized controlled trial (RCT) aimed to compare the clinical outcomes of thoracolumbar burst fractures (TLBFs) treated with open reduction and internal fixation via the posterior paraspinal muscle approach (PPMA) and the post-middle approach (PA). METHODS:Patients with a traumatic single-level TLBFs (T10-L2), treated at our hospital between December 2009 and December 2014, were randomly allocated to Group A (PPMA) and Group B (PA). Sex, age, time from injury to surgery, the American Spinal Injury Association Impairment Scale score (ASIAIS), comorbidities, vertebral level, pre- and postoperative kyphotic angle (KA), visual analog scale (VAS) pain score, and the Oswestry Disability Index (ODI) scores were included in the analysis. Operative time, intraoperative blood loss, x-ray exposure time, postoperative drainage volume, superficial infection, and occurrence of deep infection were documented. The patients were followed up at 2 weeks; 1, 3, and 6 months; 1 and 2 years; and every 6 months thereafter. Radiological assessments were performed to assess fracture union and detect potential loosening and breakage of the pedicle screws and rods at each follow-up. Postoperative VAS and ODI scores were used to evaluate the clinical outcomes. RESULTS:A total of 62 patients were enrolled (30 in Group A and 32 in Group B, respectively). The operative time (P < .001) and x-ray exposure time (P < .001) in Group A were significantly longer than those in Group B. However, compared to Group B, there were less intraoperative blood loss (P < .001), lower postoperative drainage volume (P < .001), lower VAS scores (2-week (P = .029), 1-month (P = .023), 3-month (P = .047), and 6-month follow-up (P = .010)), and lower ODI scores (2-week, P = .010; 1-month, P < .001; 3-month, P = .028; and 6-month follow-up, P = .033) in Group A. CONCLUSIONS:Although PPMA required a longer operative time and x-ray exposure time, PPMA provided several advantages over PA, including less intra-operative blood loss and lower postoperative drainage volume, and greater satisfaction with postoperative pain relief and functional improvement, than PA, especially at the 6-month follow-up after surgery. Further high-quality multicenter studies are warranted to validate our findings.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Chang W,Zhang D,Liu W,Lian X,Jiao Z,Chen Wdoi
10.1097/MD.0000000000011193subject
Has Abstractpub_date
2018-06-01 00:00:00pages
e11193issue
25eissn
0025-7974issn
1536-5964pii
00005792-201806220-00072journal_volume
97pub_type
杂志文章,随机对照试验相关文献
MEDICINE文献大全abstract::To assess whether the pattern of presentation and the outcome of monoclonal gammopathy of undetermined significance (MGUS) have changed over the last 3 decades, we evaluated 1400 patients, divided into 3 groups: group I (1975-1987), group II (1988-1997), and group III (1998-2007). We observed a significant increase in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0b013e3181e763be
更新日期:2010-07-01 00:00:00
abstract:RATIONALE:Infertile male carrying balanced translocations can be broadly divided into two types: pregestational and gestational infertility. Chromosome and breakpoints involved translocation should be considered in genetic counselling for these patients. To date, > 100 cases have been described with carrying balanced t...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000010452
更新日期:2018-04-01 00:00:00
abstract::Many people exposed to torture later suffer from torture-related post-traumatic stress disorder (TR-PTSD). The aim of this study was to analyze the morphologic and functional brain changes in patients with TR-PTSD using magnetic resonance imaging (MRI) and positron emission tomography (PET). This study evaluated 19 su...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003387
更新日期:2016-04-01 00:00:00
abstract::This article explores information relating to female adolescents knowledge, attitudes, and behaviors toward human immunodeficiency virus (HIV) and other sexually transmitted diseases (STDs) in Carriacou. The authors aimed at finding out whether adolescent females in Carriacou receive adequate information about HIV and...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004800
更新日期:2016-09-01 00:00:00
abstract::Pasteurella multocida, a small, gram-negative coccobacillus , is part of the normal oral flora of many animals, including the dog and cat. P. multocida is the etiologic agent in a variety of infectious disease syndromes. We have reported 34 cases of infection caused by P. multocida and have reviewed the English litera...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:
更新日期:1984-05-01 00:00:00
abstract:RATIONALE:Intraductal papillary mucinous neoplasms of the pancreas (IPMNs) are benign cystic tumors with a relevant risk of malignant transformation over time. Currently, follow-up after surgical resection of benign IPMNs remains controversial. PATIENT CONCERNS:This is a case report of a 68-year-old male who underwent...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009894
更新日期:2018-02-01 00:00:00
abstract:RATIONALE:Cranial arterial air embolism is a rare but potentially fatal complication after computed tomography (CT)-guided pulmonary interventions. PATIENT CONCERNS:A 64-year-old man was diagnosed with a pulmonary nodule (diameter: approximately 1 cm) in the right lower lobe. The patient developed convulsions after CT...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015437
更新日期:2019-05-01 00:00:00
abstract:RATIONALE:Acute cerebral infarction after snake bites is rare. The underlying mechanism causing the thrombotic process remains complex and unknown. PATIENT CONCERNS:We herein describe a 49-year-old female who was bitten by a Trimeresurus stejnegeri. After 4 days of biting, she developed acute ischemic infarct. DIAGNO...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015684
更新日期:2019-06-01 00:00:00
abstract::Multilevel cervical reconstruction and fusion after cervical tuberculosis has always been a challenge. The current implantation materials for cervical fusion, including titanium mesh, cage, and plate are limited by its inferior biological mechanical characteristics and the properties of the metallic material. This has...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009382
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:To evaluate the analgesic efficacy on defined areas of the abdomen and back after ultrasound-guided subcostal transversus abdominis plane (TAP) block using 0.25% levobupivacaine 0.5 mL/kg. METHODS:Twenty patients undergoing elective laparoscopic cholecystectomy, between 20 and 60 years of age with operative...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000006309
更新日期:2017-03-01 00:00:00
abstract::This article evaluates the long-term outcomes of computed tomography (CT)-guided percutaneous radiofrequency thermocoagulation (PRT) for patients with recurrent trigeminal neuralgia (TN) after microvascular decompression (MVD).This is a retrospective study of 41 patients with intractable TN who after MVD underwent CT-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001176
更新日期:2015-08-01 00:00:00
abstract:OBJECTIVE:This study aimed to explore the cost-effectiveness of etanercept plus methotrexate (ETN+MTX) compared to triple disease-modifying anti-rheumatic drugs (DMARDs) in treating Chinese rheumatoid arthritis (RA) patients. METHODS:The 134 Chinese RA patients who were about to initiate ETN+MTX or triple DMARDs thera...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016635
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Our study aimed to screen and explore the expression of inflammatory factors in keloid patients and to investigate how hyperbaric oxygen (HBO) therapy affects the expression levels of interleukin-12p40 (IL-12p40), macrophage inflammatory protein-1β (MIP-1β), platelet-derived growth factor-BB (PDGF-BB), and i...
journal_title:Medicine
pub_type: 临床试验,杂志文章
doi:10.1097/MD.0000000000019857
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Cardiac myxomas are the most frequent primary cardiac tumor in adults. The incidence in pediatric patients is extremely low. Heavy calcification of an atrial myxoma is uncommon in children. CASE PRESENTATION:An 18-month-old boy was admitted for a significant precordial systolic murmur. Transthoracic echoc...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011073
更新日期:2018-06-01 00:00:00
abstract:RATIONALE:Total hip arthroplasty (THA) concomitant with subtrochanteric femoral shortening osteotomy for Crowe type IV dysplastic hip has been reported. However, the combination of subtrochanteric femoral osteotomy and revision THA has only been mentioned in one case report. PATIENT CONCERNS:A 67-year-old female had a...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012934
更新日期:2018-10-01 00:00:00
abstract:RATIONALE:The treatment of osteogenesis imperfecta (OI) requires a multidisciplinary approach to maximize function and reduce fracture incidence. The aim of this case report was to discuss an alternative surgical approach to stabilize a corrective osteotomy using the Fassier Duval (FD) system in an OI patient. PATIENT...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008459
更新日期:2017-11-01 00:00:00
abstract:OBJECTIVE:Numerous studies have shown that lymphovascular invasion (LVI) is linked to biochemical recurrence (BCR) in prostate cancer (PCa) patients following radical prostatectomy (RP). However, the actual clinicopathological impacts of LVI remain unclear. Thus, we performed a meta-analysis to evaluate the pathologic ...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013537
更新日期:2018-12-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000006944.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/MD.0000000000007458
更新日期:2017-06-30 00:00:00
abstract::Venous thromboembolism (VTE) is a preventable cause of morbidity and mortality in acutely ill patients hospitalized in medical departments. Thromboprophylaxis with anticoagulants was shown to be safe and effective in medical patients with high risk to develop VTE. Despite guidelines recommendations, the rate of thromb...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000019127
更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:The benefit of a procalcitonin (PCT)-guided antibiotic strategy in acute exacerbation of chronic obstructive pulmonary disease (AECOPD) remains uncertain. OBJECTIVES:This updated meta-analysis was performed to reevaluate the therapeutic potential of PCT-guided antibiotic therapy in AECOPD. DATA SOURCES:We ...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000016775
更新日期:2019-08-01 00:00:00
abstract::Atrial fibrillation (AF), the most common cardiac arrhythmia, is a major risk factor for thromboembolic events, especially ischemic stroke. Catheter ablation is an effective method to maintain sinus rhythm in patients with AF. Although some observational studies have shown a relatively lower stroke rate after catheter...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000008479
更新日期:2017-12-01 00:00:00
abstract:ABSTRACT:Colorectal cancer is a heterogeneous disease with multiple epigenetic alterations and different molecular features. The molecular classification is based on 2 major distinct pathways: microsatellite stable pathway and the microsatellite instability pathway. Molecular profiling of colorectal cancer provides imp...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000024062
更新日期:2021-01-08 00:00:00
abstract::We sought to investigate the association of preoperative fibrinogen levels with clinicopathologic outcomes after surgical treatment of nonmetastatic renal cell carcinoma. We reviewed the records of 1511 patients who had their fibrinogen levels measured preceding surgery. The associations between preoperative fibrinoge...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000002626
更新日期:2016-01-01 00:00:00
abstract::Meckel diverticulum is the most prevalent congenital abnormality of the gastrointestinal tract in children. The aim of this study was to review and analyze clinical data on the diagnosis and management of Meckel diverticulum in pediatric patients. The records of 102 pediatric patients (<14 years old) who underwent sur...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000007760
更新日期:2017-08-01 00:00:00
abstract:RATIONALE:About 60,0000 people are involved in traffic accident each year in China and spinal cord injury (SCI) often occurs. Pregnant women with paraplegia is rare, and they face higher risk during pregnancy and childbirth. PATIENT CONCERNS:We report a case of a 35-year-old patient with SCI, who had vaginal forceps d...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010445
更新日期:2018-04-01 00:00:00
abstract::The aim of this study is to report first preliminary results of patients enrolled in a phase II study that will investigate the activity and safety of docetaxel, oxaliplatin, and 5-fluorouracil (DOF) in combination with trastuzumab in human epidermal receptor-2 (HER-2) positive patients with advanced gastric or gastro...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000010745
更新日期:2018-05-01 00:00:00
abstract::Mannitol is widely used to reduce intracranial pressure and is protective against ischemic and nephrotoxic acute renal failure. However, the capacity of this seemingly innocuous agent to produce acute renal failure is not well recognized. We report herein the clinical course of 8 cases of mannitol-induced acute renal ...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/00005792-199005000-00003
更新日期:1990-05-01 00:00:00
abstract::In a review of endocarditis caused by fastidious, slow-growing gram-negative rods, similarities in the spectrum of disease overshadow differences among cases grouped by specific organisms. Cardiobacterium hominis, Actinobacillus actinomycetemcomitans and Haemophilus species usually seed previously damaged cardiac valv...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/00005792-197903000-00003
更新日期:1979-03-01 00:00:00
abstract:RATIONALE:To report a patient with primary progressive freezing gait (PPFG) whose degeneration of corticofugal tract (CFT) from the supplementary motor area (SMA) was demonstrated using diffusion tensor tractography (DTT). PATIENT CONCERNS:A 66-year-old woman presented with a solitary symptom of a sudden transient bre...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000006840
更新日期:2017-05-01 00:00:00
abstract::This case series aimed to preliminarily evaluate the efficacy and safety of drug-eluting beads transarterial chemoembolization (DEB-TACE) in patients with lung, renal, gastric, and other non-liver cancers.Twenty-four patients who underwent DEB-TACE or DEB-TACE combined with other therapies were reviewed in this case s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020878
更新日期:2020-07-31 00:00:00