Abstract:
:
journal_name
Drug Safjournal_title
Drug safetyauthors
Kawada Tdoi
10.1007/s40264-018-0670-2subject
pub_date
2018-06-01 00:00:00pages
641-642issue
6eissn
0114-5916issn
1179-1942pii
10.1007/s40264-018-0670-2journal_volume
41pub_type
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abstract:BACKGROUND AND PURPOSE:Selective serotonin reuptake inhibitors (SSRIs) are frequently prescribed in the elderly due to a more favorable risk profile than other antidepressants (ADs). However, SSRIs are associated with an increased risk of gastrointestinal bleeding, while evidence on the risk of hemorrhagic stroke (HS) ...
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abstract::Quinolones are a class of antibacterial agents for the treatment of several infectious diseases (e.g. urinary and respiratory tract infections). They are used worldwide due to their broad spectrum of activity, high bioavailability and good safety profile. The safety profile varies from quinolone to quinolone. The aim ...
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更新日期:2004-01-01 00:00:00
abstract:INTRODUCTION:Detecting signals of safety concerns associated with complementary medicines (CMs) relies on spontaneous reports submitted by health professionals and patients/consumers. Community pharmacists are well placed to identify and report suspected adverse drug reactions (ADRs) associated with CMs, but pharmacist...
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doi:10.1007/s40264-020-00980-x
更新日期:2020-11-01 00:00:00
abstract::Severe skin adverse drug reactions can result in death, but the rate of such events is fortunately low. The incidences of Stevens-Johnson syndrome and toxic epidermal necrolysis range from 1.2 to 6 per million per year and 0.4 to 1.2 per million per year, respectively. Stevens-Johnson syndrome is fatal in about 5% and...
journal_title:Drug safety
pub_type: 杂志文章,评审
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更新日期:1995-07-01 00:00:00
abstract::Transdermal fentanyl is effective and well tolerated for the treatment of chronic pain caused by malignancy and non-malignant conditions when administered according to the manufacturer's recommendations. Compared with oral opioids, the advantages of transdermal fentanyl include a lower incidence and impact of adverse ...
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pub_type: 杂志文章,评审
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更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Newly approved drugs, in comparison with older drugs, are more often prescribed to patients who have not responded satisfactorily to established related drugs or as first-line therapy to patients with a high baseline risk for adverse outcomes (i.e. channelling). However, these patients are less likely to ben...
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更新日期:2008-01-01 00:00:00
abstract::Osteoporosis is the most frequent metabolic condition experienced by elderly individuals. It is characterised by a low bone mass and microarchitectural deterioration of bone tissue leading to an increase in bone fragility and susceptibility to fracture. Osteoporosis constitutes a significant financial burden for healt...
journal_title:Drug safety
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更新日期:1998-08-01 00:00:00