Abstract:
:The epithelium of the human fallopian tube (oviduct) and cervix were studied by histological, immunohistological, and ultrastructural methods with a view to establishing the nature of the so called "basal" and "reserve" cells. The results indicated that the "basal" cells of the oviductal epithelia were T lymphocytes, with a predominance of T cytotoxic and suppressor cells. A more heterogeneous inflammatory cell population was present in cervical epithelium, although once again T cytotoxic and suppressor cells were the most numerous subtype. The intraepithelial inflammatory cells were quite distinct from the cells commonly referred to as "reserve" cells (reserve cell hyperplasia), which have epithelial characteristics. The origin of the "reserve" cells is unclear, but they seem to arise within the epithelium. They probably represent an early sign of squamous metaplasia. The lymphoid tissue of fallopian tube and endocervix shows similarities with that of the endometrium and mucosal associated lymphoid tissue in general.
journal_name
J Clin Patholjournal_title
Journal of clinical pathologyauthors
Peters WMdoi
10.1136/jcp.39.3.306subject
Has Abstractpub_date
1986-03-01 00:00:00pages
306-12issue
3eissn
0021-9746issn
1472-4146journal_volume
39pub_type
杂志文章abstract::The activities of three commercial products of papain were compared as supplied and after activation, and when used in the enzyme-serum method for rhesus (D) grouping. Certain dangers in activation became apparent, and accurate determination of the proportions of papain to anti-D appeared more important than indiscrim...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.15.6.503
更新日期:1962-11-01 00:00:00
abstract::Immunoreactive plasminogen activators were studied in tissue sections using a peroxidase method and monospecific antibodies to tissue plasminogen activator produced by a melanoma. Tissue plasminogen activator reactivity was found in skin melanomas and in endothelial and smooth muscle cells of arteries and veins. Vesse...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.38.2.140
更新日期:1985-02-01 00:00:00
abstract::Circulating immune complexes have been detected in the sera of 24 Nigerian children with acute poststreptococcal glomerulonephritis using two methods. There was a significant correlation between levels of soluble complexes, detected in samples taken from patients in the oliguric phase of acute nephritis, and severity ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.31.9.817
更新日期:1978-09-01 00:00:00
abstract::Of the first 250 heart and 35 heart and lung transplant recipients at Papworth Hospital, Cambridge, who survived for more than one month after transplantation, 217 heart and 33 heart and lung patients were investigated serologically for evidence of Toxoplasma gondii infection. Six patients acquired primary T gondii in...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.42.2.194
更新日期:1989-02-01 00:00:00
abstract::Streptex was compared to routine laboratory identification methods available. The results from Streptex sometimes required several attempts before final identification could be achieved. In the main, group D streptococci other than Strep. faecalis failed to group with the Streptex antisera, and this method cannot ther...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.32.12.1234
更新日期:1979-12-01 00:00:00
abstract::Programmed death ligand 1 (PD-L1) is the principal ligand of programmed death 1 (PD-1), a coinhibitory receptor that can be constitutively expressed or induced in myeloid, lymphoid, normal epithelial cells and in cancer. Under physiological conditions, the PD-1/PD-L1 interaction is essential in the development of immu...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jclinpath-2017-204853
更新日期:2018-03-01 00:00:00
abstract:AIM:To assess the clinical value of malignancy grading systems compared with nuclear DNA content, protein p53, and angiogenesis for predicting recurrence of stage I (UICC, 1987) tongue carcinomas. METHODS:Histopathological malignancy grading according to Jakobsson and tumour front grading according to Bryne et al were...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.52.1.35
更新日期:1999-01-01 00:00:00
abstract::Five cases of malignant histiocytosis of the intestine and one case of true histiocytic lymphoma were studied using immunohistological techniques. In paraffin sections tumour cells in all cases were shown to contain alpha-1-antitrypsin and to express the leucocyte common antigen. Four of the five cases of malignant hi...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.39.1.8
更新日期:1986-01-01 00:00:00
abstract::Thirteen meningiomas of varying light microscopic features were studied immunohistologically using a panel of monoclonal antibodies directed against epithelial, mesenchymal, and neural components. All 13 meningiomas showed expression of epithelial membrane antigen, vimentin, and S100 protein, as did normal meninges. F...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.39.4.435
更新日期:1986-04-01 00:00:00
abstract:AIMS:To compare the efficacy of and tolerance to oral fluconazole and intraconazole in preventing fungal infection in neutropenic patients with haematological malignancies. PATIENTS:213 consecutive, afebrile adult patients treated with or without autologous stem cell transplantation for haematological malignancies. M...
journal_title:Journal of clinical pathology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/jcp.52.5.376
更新日期:1999-05-01 00:00:00
abstract::In order to classify the underlying disorder in four patients with biopsy-proven amyloidosis without overt monoclonal gammopathy, the cytoplasmic immunoglobulin (Ig) distribution of bone marrow plasma cells was evaluated using direct immunofluorescence microscopy. This procedure revealed the presence of a monoclonal p...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.35.3.285
更新日期:1982-03-01 00:00:00
abstract:AIMS:The aims of this study were (1) to determine the measurement accuracy of a widely used guaiac faecal occult blood test (gFOBT) compared with an immunochemical faecal occult blood test (iFOBT) during in vitro studies, including their analytical stability over time at ambient temperature and at 4°C; and (2) to compa...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2010.085399
更新日期:2011-06-01 00:00:00
abstract:AIMS:To investigate whether cholesterol and lactate dehydrogenase (LDH) measurements in fluids are more sensitive and specific markers for differentiating between exudates and transudates, as confirmed clinically, than the measurement of fluid total protein concentrations alone. PATIENTS/METHODS:Serum, pleural fluid, ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.55.1.69
更新日期:2002-01-01 00:00:00
abstract::The thyroids of primary thyrotoxicosis patients prepared for partial thyroidectomy with propranolol contained much more lymphoid infiltrate than those prepared with carbimazole. No relation was found between the extent of lymphoid infiltrate in the thyroid and the development of postoperative hypothyroidism either bet...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.29.5.398
更新日期:1976-05-01 00:00:00
abstract:AIMS:To study the pathogenicity and virulence characteristics of Staphylococcus epidermidis, Staphylococcus haemolyticus, and Staphylococcus sapro-phyticus. METHODS:BALB/c mice were challenged intraperitoneally with graded doses of three strains belonging to each species. LD50s were measured for each strain. Haemolysi...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.47.8.743
更新日期:1994-08-01 00:00:00
abstract:AIM:We examined the genetic alterations in a mother and son with multiple eosinophilic chromophobe renal cell carcinomas (chRCCs) showing no other features. METHODS:Germline DNA and bilateral renal cell carcinoma DNA were genetically analysed by whole-exome sequencing. Candidate gene alterations in the first patient's...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2018-205211
更新日期:2018-10-01 00:00:00
abstract::A commercial latex slide test (Oxoid DR 620) for the identification of Escherichia coli O157 was compared with a standard tube agglutination method using E coli O157 antiserum (Difco). Thirty isolates previously confirmed as E coli O157 were positive by both methods: 30 isolates of E coli of serogroups other than O157...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.42.10.1109
更新日期:1989-10-01 00:00:00
abstract::An indirect immunoperoxidase technique has been used for visualisation of cellular immunoglobulins in chronic lymphocytic leukaemia. Baker's formol calcium was used as fixative. Monoclonal light and heavy chain patterns were demonstrated in 24 out of 27 cases. Only one case did not have any demonstrable immunoglobulin...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.36.12.1391
更新日期:1983-12-01 00:00:00
abstract::Gastroblastoma is a rare gastric epitheliomesenchymal biphasic tumour composed of spindle and epithelial cells, reported by Miettinen et al in a series of three cases in 2009. All those cases arose in stomachs of young adults. Neither the epithelial nor the mesenchymal component displayed sufficient atypia to diagnose...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.2009.074104
更新日期:2010-03-01 00:00:00
abstract::The results of an investigation show that there is no statistically significant excess of blood group A in cases of carcinoma of the oesophagus or in cases of benign prostatic hyperplasia. ...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.17.1.42
更新日期:1964-01-01 00:00:00
abstract:BACKGROUND:Ewing's sarcoma and peripheral primitive neuroectodermal tumour (pPNET) are now regarded as two morphological ends of a spectrum of neoplasms, characterised by a t(11;22) or other related chromosomal translocation involving the EWS gene on chromosome 22 and referred to as Ewing family of tumours (EFTs). EFTs...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jcp.2006.040931
更新日期:2007-06-01 00:00:00
abstract::Digital pathology (DP) and whole-slide imaging (WSI) technology have matured substantially over the last few years and there is growing evidence from validation studies that WSI is comparable to glass slides for histopathology diagnosis, although with some limitations, which can be appropriately minimised. Whether the...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jclinpath-2016-204272
更新日期:2017-05-01 00:00:00
abstract::In the past decade, cellular immunophenotyping has become a new discipline in diagnostic haematology and immunology, and is invaluable in the rapid diagnosis of leukaemia and monitoring disease progression in human immunodeficiency virus infected individuals. The introduction of bench top flow cytometers has meant tha...
journal_title:Journal of clinical pathology
pub_type: 杂志文章,评审
doi:10.1136/jcp.54.7.508
更新日期:2001-07-01 00:00:00
abstract:AIMS:To investigate the association of cagA positivity and non-opsonic neutrophil activation capacity in wild-type Helicobacter pylori strains with peptic ulcer disease or chronic gastritis only. METHODS:Helicobacter pylori were isolated from antral biopsies of 53 consecutive patients with chronic antral gastritis, of...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.53.4.318
更新日期:2000-04-01 00:00:00
abstract::Four assays for the detection of alphafetoprotein (AFP) in the diagnosis of primary hepatocellular carcinoma (HCC) were evaluated. The frequency of AFP detection was compared in 89 HCC patients and in 71 patients with chronic active hepatitis/cirrhosis. Of the four assays, immunodiffusion, counterimmunoelectrophoresis...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.33.8.792
更新日期:1980-08-01 00:00:00
abstract::Painful lymphadenopathy developed in eight female patients after massive infusions of iron dextran for sideropaenic anaemia. Fever, arthralgias, and malaise were also features of the clinical picture. The histology of one lymph node is described and changes in it are discussed in relation to the pathogenesis of the sy...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.21.4.492
更新日期:1968-07-01 00:00:00
abstract::In the present investigation, the prevalence of focal lymphocytic adenitis in the submandibular salivary gland was observed in a series of 116 postmortem subjects after suitable exclusions had been made. Focal lymphocytic adenitis could not be demonstrated in the labial salivary glands. The degree of lymphocytic infil...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.23.8.690
更新日期:1970-11-01 00:00:00
abstract::This paper illustrates a simple method of necropsy dissection of the abdominal organs after abdominal surgery. The organs are removed in one block as per the method described by Letulle. A retroperitoneal approach is then used. Structures are dissected away in a series of layers using the vasculature for guidance. Thi...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.49.9.776
更新日期:1996-09-01 00:00:00
abstract:AIMS:The development of a technique for simultaneous in situ hybridisation for native mRNA and conventional immunofluorescence for cytoplasmic antigens in routine pathology specimens. METHODS:Cocktails of synthetic deoxyoligonucleotides coding for immunoglobulin J chain and kappa light chain were 3' end labelled enzym...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.45.2.114
更新日期:1992-02-01 00:00:00
abstract::A competitive enzyme linked immunosorbent assay (ELISA) method was used to measure the concentration of lactoferrin in fluids from 36 odontogenic keratocysts, 15 dentigerous cysts, and 30 radicular/residual cysts. Keratocyst fluids contained significantly higher concentrations of lactoferrin than fluids from the other...
journal_title:Journal of clinical pathology
pub_type: 杂志文章
doi:10.1136/jcp.42.2.180
更新日期:1989-02-01 00:00:00