Model of Murine Ventricular Cardiac Tissue for In Vitro Kinematic-Dynamic Studies of Electromagnetic and β-Adrenergic Stimulation.

Abstract:

:In a model of murine ventricular cardiac tissue in vitro, we have studied the inotropic effects of electromagnetic stimulation (frequency, 75 Hz), isoproterenol administration (10 μM), and their combination. In particular, we have performed an image processing analysis to evaluate the kinematics and the dynamics of beating cardiac syncytia starting from the video registration of their contraction movement. We have found that the electromagnetic stimulation is able to counteract the β-adrenergic effect of isoproterenol and to elicit an antihypertrophic response.

journal_name

J Healthc Eng

authors

Fassina L,Cornacchione M,Pellegrini M,Mognaschi ME,Gimmelli R,Isidori AM,Lenzi A,Magenes G,Naro F

doi

10.1155/2017/4204085

subject

Has Abstract

pub_date

2017-01-01 00:00:00

pages

4204085

eissn

2040-2295

issn

2040-2309

journal_volume

2017

pub_type

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