Anti-TNF-α Use During the Third Trimester of Pregnancy in Women with Moderate-severe Inflammatory Bowel Disease and the Risk of Preterm Birth and Low Birth Weight.

abstract：:Crohn's disease and ulcerative colitis are quite often complicated with manifestations in extraintestinal organs like joints, eye, and skin. Although the etiopathogenesis of these nonmucosal complications remains unsettled, they all share the characteristic feature of inappropriate leukocyte recruitment in nonlymphati...

journal_title：Inflammatory bowel diseases

authors： Salmi M,Jalkanen S

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:To explore the relationship between personality and disease-specific quality of life [Inflammatory Bowel Disease Questionnaire (IBDQ)] in distressed [Perceived Stress Questionnaire (PSQ)] patients with ulcerative colitis (UC) and Crohn's disease (CD). METHODS:Included in the study were 56 patients with UC a...

journal_title：Inflammatory bowel diseases

authors： Boye B,Jahnsen J,Mokleby K,Leganger S,Jantschek G,Jantschek I,Kunzendorf S,Benninghoven D,Wilhelmsen I,Sharpe M,Blomhoff S,Malt UF,Lundin KE

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Practical and objective instruments to assess pediatric Crohn's disease (CD) activity are required for observational research and quality improvement. The objectives were: 1) to determine the feasibility of completing the Pediatric Crohn's Disease Activity Index (PCDAI) and the Abbreviated PCDAI (APCDAI); an...

journal_title：Inflammatory bowel diseases

authors： Kappelman MD,Crandall WV,Colletti RB,Goudie A,Leibowitz IH,Duffy L,Milov DE,Kim SC,Schoen BT,Patel AS,Grunow J,Larry E,Fairbrother G,Margolis P

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:A novel family of proton-sensing G protein-coupled receptors, including OGR1, GPR4, and TDAG8, was identified to be important for physiological pH homeostasis and inflammation. Thus, we determined the function of proton-sensing OGR1 in the intestinal mucosa. MTEHODS:OGR1 expression in colonic tissues was in...

journal_title：Inflammatory bowel diseases

authors： de Vallière C,Wang Y,Eloranta JJ,Vidal S,Clay I,Spalinger MR,Tcymbarevich I,Terhalle A,Ludwig MG,Suply T,Fried M,Kullak-Ublick GA,Frey-Wagner I,Scharl M,Seuwen K,Wagner CA,Rogler G

更新日期：2015-06-01 00:00:00

abstract：SUMMARY:: In recent years, heparin has emerged as a possible therapy for inflammatory bowel disease (IBD). Several recent, strongly positive, open-labeled series of heparin in both ulcerative colitis (UC) and Crohn's disease (CD) reinforce the work of Gaffney and co-workers that suggested a benefit of heparin in UC. Al...

journal_title：Inflammatory bowel diseases

authors： Korzenik JR

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Although dysplasia is thought to be the precursor lesion in the development of colitis-associated colorectal cancer (CRC), a significant proportion of patients with ulcerative colitis (UC) and low-grade (LGD) or indefinite (IND) dysplasia remain cancer-free during endoscopic follow-up. There is a need for bi...

journal_title：Inflammatory bowel diseases

authors： van Schaik FD,Oldenburg B,Offerhaus GJ,Schipper ME,Vleggaar FP,Siersema PD,van Oijen MG,Ten Kate FJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Caspase activation and recruitment domain 3 (CARD3) is a 61-kDa protein kinase. Recent evidence shows the importance of CARD3 in the immune response and inflammatory diseases. To elucidate its impact on inflammatory bowel disease, we studied the effects of the loss of CARD3 in the acute dextran sodium sulfat...

journal_title：Inflammatory bowel diseases

authors： Yu SJ,Liu Y,Deng Y,Zhu XY,Zhan N,Dong WG

更新日期：2015-04-01 00:00:00

abstract：PURPOSE:To describe the reported health-related quality of life (HRQOL) in children and adolescents with inflammatory bowel disease (IBD) after attending an IBD summer camp. METHODS:A prospective analysis of quality of life was completed at an overnight camp that was exclusively for patients with IBD, which was sponso...

journal_title：Inflammatory bowel diseases

authors： Shepanski MA,Hurd LB,Culton K,Markowitz JE,Mamula P,Baldassano RN

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:L-arginine (L-Arg) is the substrate for both inducible nitric oxide (NO) synthase (NOS2) and arginase (ARG) enzymes. L-Arg is actively transported into cells by means of cationic amino acid transporter (SLC7) proteins. We have linked L-Arg and arginase 1 activity to epithelial restitution. Our aim was to det...

journal_title：Inflammatory bowel diseases

authors： Coburn LA,Horst SN,Allaman MM,Brown CT,Williams CS,Hodges ME,Druce JP,Beaulieu DB,Schwartz DA,Wilson KT

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The relative contribution of psychological factors to the onset and course of inflammatory bowel diseases (IBD) is a matter of constant debate since its beginning, as is the clinical need and the efficacy of psychotherapeutic interventions. However, the perspective of patients with IBD has largely been ignor...

journal_title：Inflammatory bowel diseases

authors： Klag T,Mazurak N,Fantasia L,Schwille-Kiuntke J,Kirschniak A,Falch C,Goetz M,Malek NP,Enck P,Wehkamp J

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND:Intestinal stenosis is a frequent complication of Crohn's disease, often leading to repeated bowel obstruction and surgery. The prevalence of small bowel stenosis has ranged from 20% to 40% and from 7% to 15% in patients with colonic disease. Although balloon dilation is the initial preferred approach, many ...

journal_title：Inflammatory bowel diseases

authors： Swaminath A,Lichtiger S

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:MicroRNAs (miRNAs) are dysregulated in the inflammatory bowel diseases, Crohn's disease (CD) and ulcerative colitis (UC), which arise due to dysfunctional host-microbe interactions and impairment of the barrier function of the intestine. Here, we sought to determine whether circulating miRNAs are biomarkers ...

journal_title：Inflammatory bowel diseases

authors： Krissansen GW,Yang Y,McQueen FM,Leung E,Peek D,Chan YC,Print C,Dalbeth N,Williams M,Fraser AG

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Adipose tissue is recognized as a compartment secreting highly active molecules. Creeping fat represents a characteristic feature of Crohn's disease (CD). Proinflammatory or anti-inflammatory adipose-derived secretory products, now generally called adipocytokines, may play a role in the pathogenesis of CD. ...

journal_title：Inflammatory bowel diseases

authors： Paul G,Schäffler A,Neumeier M,Fürst A,Bataillle F,Buechler C,Müller-Ladner U,Schölmerich J,Rogler G,Herfarth H

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Easily accessible predictors of disease course in inflammatory bowel disease (IBD) are scarce, and it remains largely unknown whether a family history of IBD predicts the course of Crohn's disease (CD) and ulcerative colitis (UC). We aimed to compare the course of disease in familial and sporadic cases of IB...

journal_title：Inflammatory bowel diseases

authors： Trier Moller F,Andersen V,Andersson M,Jess T

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Mesalamine is the first-line drug for the treatment of ulcerative colitis (UC). We directly compared the efficacy and safety of two mesalamine formulations for the induction of remission in patients with UC. METHODS:In a multicenter, double-blind, randomized study, 229 patients with mild-to-moderate active ...

journal_title：Inflammatory bowel diseases

authors： Ito H,Iida M,Matsumoto T,Suzuki Y,Sasaki H,Yoshida T,Takano Y,Hibi T

更新日期：2010-09-01 00:00:00

abstract：BACKGROUND:The women's health aspect of inflammatory bowel disease (IBD) is a newer area of study; childbearing issues have received little attention despite the fact that IBD affects women predominantly during their childbearing years. The aim of this study was to better understand patients' considerations about pregn...

journal_title：Inflammatory bowel diseases

authors： Marri SR,Ahn C,Buchman AL

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel disease affects the quality of a patient's life in many ways, but no validated instrument for measuring disease-specific quality of life in these patients is available for use in Mainland China. The aim of our study was to develop and validate the Mainland Chinese translation of the Inflam...

journal_title：Inflammatory bowel diseases

authors： Ren WH,Lai M,Chen Y,Irvine EJ,Zhou YX

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Substance use disorders (SUDs) impose a substantial individual and societal burden; however, the prevalence and associated factors in persons with inflammatory bowel disease (IBD) are largely unknown. We evaluated the prevalence and risk factors of SUD in an IBD cohort. METHODS:Inflammatory bowel disease pa...

journal_title：Inflammatory bowel diseases

authors： Carney H,Marrie RA,Bolton JM,Patten SB,Graff LA,Bernstein CN,Kowalec K

更新日期：2021-01-01 00:00:00

abstract：:The diagnosis of inflammatory bowel disease (IBD) is traditionally based on a combination of clinical, endoscopic, histological, and radiological criteria. However, further testing is needed in cases of diagnostic uncertainty and in predicting disease course. This systematic review focuses on the potential for 10 sero...

journal_title：Inflammatory bowel diseases

authors： Prideaux L,De Cruz P,Ng SC,Kamm MA

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:The incidence of ulcerative colitis (UC) varies between Western and Eastern ethnicities. A distinct genetic background may play a role in the differences. Until now, very little was known of the UC genetics in Asian populations. Here we performed a haplotype-based analysis of six known UC susceptibility loci...

journal_title：Inflammatory bowel diseases

authors： Shi J,Zhou L,Zhernakova A,Qian J,Zhu F,Sun G,Zhu L,Ma X,Dijkstra G,Wijmenga C,Faber KN,Lu X,Weersma RK

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Interleukin (IL)-6/signal transducers and activators of transcription 3 (STAT3) signaling plays an important role in the development of colitis-associated colorectal cancer (CAC). The mechanism of CAC formation remains unclear, and the relationship between miRNAs and the IL-6/STAT3 signaling pathway in the d...

journal_title：Inflammatory bowel diseases

authors： Wang A,Deng S,Chen X,Yu C,Du Q,Wu Y,Chen G,Hu L,Hu C,Li Y

更新日期：2020-03-04 00:00:00

abstract：Background:Tumor necrosis factor alpha (TNF-α) inhibitors are linked with increased risk of reactivation of active tuberculosis. The QuantiFERON-TB Gold In-Tube test is approved for screening latent tuberculosis infection in children and adults. There are limited data on the test performance in children on long-term tr...

journal_title：Inflammatory bowel diseases

authors： Vortia E,Uko VE,Yen-Lieberman B,Frawley J,Worley SE,Danziger-Isakov L,Kaplan B,Mahajan L

更新日期：2018-03-19 00:00:00

abstract：BACKGROUND:The clinical presentation of the inflammatory bowel diseases (IBD) is extremely heterogenous and is characterized by various extraintestinal manifestations and complications (EIM). Increasing genetic insight for IBD and EIM shows multiple shared susceptibility loci. We hypothesize that, next to these overlap...

journal_title：Inflammatory bowel diseases

authors： van Sommeren S,Janse M,Karjalainen J,Fehrmann R,Franke L,Fu J,Weersma RK

更新日期：2014-06-01 00:00:00

abstract：BACKGROUND:Inflammatory bowel diseases (IBD) are characterized by intermittent relapses, and their course is heterogeneous and unpredictable. Our aim was to determine the ability of protein, metabolite, or microbial biomarkers to predict relapse in patients with quiescent disease. METHODS:This prospective study enroll...

journal_title：Inflammatory bowel diseases

authors： Borren NZ,Plichta D,Joshi AD,Bonilla G,Sadreyev R,Vlamakis H,Xavier RJ,Ananthakrishnan AN

更新日期：2020-09-18 00:00:00

abstract：BACKGROUND:Many chronic illnesses are accompanied by impaired cognitive functioning. In people with Inflammatory Bowel Disease (IBD), there is some research to suggest a decrement in verbal IQ (VIQ), when compared to people with Irritable Bowel Syndrome (IBS) and healthy controls. Although this is an important finding,...

journal_title：Inflammatory bowel diseases

authors： Dancey CP,Attree EA,Stuart G,Wilson C,Sonnet A

更新日期：2009-06-01 00:00:00

abstract：:Ulcerative colitis (UC) and Crohn's disease (CD) may directly result in morbidity and rarely mortality from complications such as colorectal cancer or sepsis. Mortality rates compared with the matched general population, measured by standardized mortality ratio, may therefore be increased. This review examines the evi...

journal_title：Inflammatory bowel diseases

authors： Selinger CP,Leong RW

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:The clinical utility of cellular therapies is being investigated in a broad range of therapeutic areas. This phase 1 study represents the first exploration of PDA001, a preparation of cells cultured from human placental tissue, in subjects with Crohn's disease. METHODS:Twelve subjects with active, moderate-...

journal_title：Inflammatory bowel diseases

authors： Mayer L,Pandak WM,Melmed GY,Hanauer SB,Johnson K,Payne D,Faleck H,Hariri RJ,Fischkoff SA

更新日期：2013-03-01 00:00:00

abstract：:Natural killer T (NKT) cells are a subset of lymphocytes that express cell surface molecules of both conventional T cells and natural killer cells and share the features of both innate and adaptive immune cells. NKT cells have been proposed to make both protective and pathogenic contributions to inflammatory bowel dis...

journal_title：Inflammatory bowel diseases

authors： van Dieren JM,van der Woude CJ,Kuipers EJ,Escher JC,Samsom JN,Blumberg RS,Nieuwenhuis EE

更新日期：2007-09-01 00:00:00

abstract：BACKGROUND:Clinical observations or animal studies implicate enteric glial cells in motility disorders, irritable bowel syndrome, inflammatory bowel disease, gastrointestinal (GI) infections, postoperative ileus, and slow transit constipation. Mechanisms underlying glial responses to inflammation in human GI tract are ...

journal_title：Inflammatory bowel diseases

authors： Liñán-Rico A,Turco F,Ochoa-Cortes F,Harzman A,Needleman BJ,Arsenescu R,Abdel-Rasoul M,Fadda P,Grants I,Whitaker E,Cuomo R,Christofi FL

更新日期：2016-08-01 00:00:00

abstract：Background:Understanding of the prevalence, pathophysiology, and management of fecal incontinence (FI) in inflammatory bowel disease (IBD) patients without an ileal pouch anal anastomosis (IPAA) is suboptimal. We conducted a systematic review and meta-analysis on the prevalence, pathophysiology, and management of prima...

journal_title：Inflammatory bowel diseases

authors： Gu P,Kuenzig ME,Kaplan GG,Pimentel M,Rezaie A

更新日期：2018-05-18 00:00:00