Abstract:
:In an attempt to investigate beta-globin gene polymorphism in the Saudi population, DNA samples were analysed using restriction endonucleases, Mst II and Hpa I. Both beta A and beta S genes showed extensive polymorphism and were found to be linked to 13.0 kb, 7.6 kb, 7.0 kb, and 5.6 kb Hpa I fragments. Three DNA samples out of a total of 436 analysed, had beta-globin gene linked to three Hpa I fragments of the sizes 13.0 kb, 7.6 kb, and 5.6 kb. In this paper we present our findings and discuss the possibility of multiple beta-globin loci.
journal_name
Hum Genetjournal_title
Human geneticsauthors
el-Hazmi MA,Jabbar FA,Al-Swailem AR,Warsy ASdoi
10.1007/BF00282555subject
Has Abstractpub_date
1986-11-01 00:00:00pages
313-5issue
3eissn
0340-6717issn
1432-1203journal_volume
74pub_type
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