Distinct herpesvirus resistances and immune responses of three gynogenetic clones of gibel carp revealed by comprehensive transcriptomes.

abstract：BACKGROUND:Leaf blight caused by Calonectria spp. is one of the most destructive diseases to affect Eucalyptus nurseries and plantations. These pathogens mainly attack Eucalyptus, a tree with a diversity of secondary metabolites employed as defense-related phytoalexins. To unravel the fungal adaptive mechanisms to vari...

journal_title：BMC genomics

authors： Ye X,Zhong Z,Liu H,Lin L,Guo M,Guo W,Wang Z,Zhang Q,Feng L,Lu G,Zhang F,Chen Q

更新日期：2018-05-10 00:00:00

abstract：BACKGROUND:The Egyptian Rousette bat (Rousettus aegyptiacus), a common fruit bat species found throughout Africa and the Middle East, was recently identified as a natural reservoir host of Marburg virus. With Ebola virus, Marburg virus is a member of the family Filoviridae that causes severe hemorrhagic fever disease i...

journal_title：BMC genomics

authors： Lee AK,Kulcsar KA,Elliott O,Khiabanian H,Nagle ER,Jones ME,Amman BR,Sanchez-Lockhart M,Towner JS,Palacios G,Rabadan R

更新日期：2015-12-07 00:00:00

abstract：BACKGROUND:Dermatophytes are the primary causative agent of dermatophytoses, a disease that affects billions of individuals worldwide. Trichophyton rubrum is the most common of the superficial fungi. Although T. rubrum is a recognized pathogen for humans, little is known about how its transcriptional pattern is related...

journal_title：BMC genomics

authors： Wang L,Ma L,Leng W,Liu T,Yu L,Yang J,Yang L,Zhang W,Zhang Q,Dong J,Xue Y,Zhu Y,Xu X,Wan Z,Ding G,Yu F,Tu K,Li Y,Li R,Shen Y,Jin Q

更新日期：2006-10-11 00:00:00

abstract：BACKGROUND:With its genome sequence and other experimental attributes, Populus trichocarpa has become the model species for genomic studies of wood development. Wood is derived from secondary growth of tree stems, and begins with the development of a ring of vascular cambium in the young developing stem. The terminal r...

journal_title：BMC genomics

authors： Dharmawardhana P,Brunner AM,Strauss SH

更新日期：2010-03-04 00:00:00

abstract：BACKGROUND:Due to the high morbidity and mortality of fulminant hepatitis, early diagnosis followed by early effective treatment is the key for prognosis improvement. So far, little is known about the gene expression changes in the early stage of this serious illness. Identification of the genes related to the very ear...

journal_title：BMC genomics

authors： Chen F,Zhu HH,Zhou LF,Li J,Zhao LY,Wu SS,Wang J,Liu W,Chen Z

更新日期：2010-04-15 00:00:00

abstract：BACKGROUND:The capsular polysaccharide is the principal virulence factor of Streptococcus pneumoniae and a target for current pneumococcal vaccines. However, some pathogenic pneumococci are serologically nontypeable [nontypeable pneumococci (NTPn)]. Due to their relative rarity, NTPn are poorly characterized, and, as s...

journal_title：BMC genomics

authors： Mohale T,Wolter N,Allam M,Ndlangisa K,Crowther-Gibson P,du Plessis M,von Gottberg A

更新日期：2016-06-22 00:00:00

abstract：BACKGROUND:Long non-coding RNAs (lncRNAs) are a new class of regulatory molecules with roles in diverse biological processes. While much effort has been invested in the analysis of lncRNAs from established plant models Arabidopsis, maize, and rice, almost nothing is known about lncRNAs from fruit crops, including those...

journal_title：BMC genomics

authors： Kang C,Liu Z

更新日期：2015-10-19 00:00:00

abstract：BACKGROUND:Human induced pluripotent stem cells (iPSCs) have a wide range of applications throughout the fields of basic research, disease modeling and drug screening. Epigenetic instable iPSCs with aberrant DNA methylation may divide and differentiate into cancer cells. Unfortunately, little effort has been taken to c...

journal_title：BMC genomics

authors： Shao X,Zhang C,Sun MA,Lu X,Xie H

更新日期：2014-11-18 00:00:00

abstract：BACKGROUND:Petal nectar spurs, which facilitate pollination through animal attraction and pollen placement, represent a key innovation promoting diversification in the genus Aquilegia (Ranunculaceae). Identifying the genetic components that contribute to the development of these three-dimensional structures will inform...

journal_title：BMC genomics

authors： Ballerini ES,Kramer EM,Hodges SA

更新日期：2019-08-22 00:00:00

abstract：BACKGROUND:Actinobacillus pleuropneumoniae is the etiological agent of porcine pleuropneumonia, a respiratory disease which causes great economic losses worldwide. Many virulence factors are involved in the pathogenesis, namely capsular polysaccharides, RTX toxins, LPS and many iron acquisition systems. In order to ide...

journal_title：BMC genomics

authors： Deslandes V,Denicourt M,Girard C,Harel J,Nash JH,Jacques M

更新日期：2010-02-08 00:00:00

abstract：BACKGROUND:Chemical bioavailability is an important dose metric in environmental risk assessment. Although many approaches have been used to evaluate bioavailability, not a single approach is free from limitations. Previously, we developed a new genomics-based approach that integrated microarray technology and regressi...

journal_title：BMC genomics

authors： Gong P,Nan X,Barker ND,Boyd RE,Chen Y,Wilkins DE,Johnson DR,Suedel BC,Perkins EJ

更新日期：2016-03-08 00:00:00

abstract：BACKGROUND:Despite its primary economic importance, genomic information on olive tree is still lacking. 454 pyrosequencing was used to enrich the very few sequence data currently available for the Olea europaea species and to identify genes involved in expression of fruit quality traits. RESULTS:Fruits of Coratina, a ...

journal_title：BMC genomics

authors： Alagna F,D'Agostino N,Torchia L,Servili M,Rao R,Pietrella M,Giuliano G,Chiusano ML,Baldoni L,Perrotta G

更新日期：2009-08-26 00:00:00

abstract：BACKGROUND:Dense single nucleotide polymorphism (SNP) genotyping arrays provide extensive information on polymorphic variation across the genome of species of interest. Such information can be used in studies of the genetic architecture of quantitative traits and to improve the accuracy of selection in breeding program...

journal_title：BMC genomics

authors： Houston RD,Taggart JB,Cézard T,Bekaert M,Lowe NR,Downing A,Talbot R,Bishop SC,Archibald AL,Bron JE,Penman DJ,Davassi A,Brew F,Tinch AE,Gharbi K,Hamilton A

更新日期：2014-02-06 00:00:00

abstract：BACKGROUND:The introduction of genome-wide shRNA and CRISPR libraries has facilitated cell-based screens to identify loss-of-function mutations associated with a phenotype of interest. Approaches to perform analogous gain-of-function screens are less common, although some reports have utilized arrayed viral expression ...

journal_title：BMC genomics

authors： Feddersen CR,Wadsworth LS,Zhu EY,Vaughn HR,Voigt AP,Riordan JD,Dupuy AJ

更新日期：2019-06-17 00:00:00

abstract：BACKGROUND:Microsatellites are widely used for many genetic studies. In contrast to single nucleotide polymorphism (SNP) and genotyping-by-sequencing methods, they are readily typed in samples of low DNA quality/concentration (e.g. museum/non-invasive samples), and enable the quick, cheap identification of species, hyb...

journal_title：BMC genomics

authors： Dawson DA,Ball AD,Spurgin LG,Martín-Gálvez D,Stewart IR,Horsburgh GJ,Potter J,Molina-Morales M,Bicknell AW,Preston SA,Ekblom R,Slate J,Burke T

更新日期：2013-03-15 00:00:00

abstract：BACKGROUND:The orphan nuclear receptor TR4 (human testicular receptor 4 or NR2C2) plays a pivotal role in a variety of biological and metabolic processes. With no known ligand and few known target genes, the mode of TR4 function was unclear. RESULTS:We report the first genome-wide identification and characterization o...

journal_title：BMC genomics

authors： O'Geen H,Lin YH,Xu X,Echipare L,Komashko VM,He D,Frietze S,Tanabe O,Shi L,Sartor MA,Engel JD,Farnham PJ

更新日期：2010-12-02 00:00:00

abstract：BACKGROUND:The increased multi-omics information on carefully phenotyped patients in studies of complex diseases requires novel methods for data integration. Unlike continuous intensity measurements from most omics data sets, phenome data contain clinical variables that are binary, ordinal and categorical. RESULTS:In ...

journal_title：BMC genomics

authors： Kim S,Herazo-Maya JD,Kang DD,Juan-Guardela BM,Tedrow J,Martinez FJ,Sciurba FC,Tseng GC,Kaminski N

更新日期：2015-11-11 00:00:00

abstract：BACKGROUND:Meta-analysis of QTLs combines the results of several QTL detection studies and provides narrow confidence intervals for meta-QTLs, permitting easier positional candidate gene identification. It is usually applied to multiple mapping populations, but can be applied to one. Here, a meta-analysis of drought re...

journal_title：BMC genomics

authors： Khowaja FS,Norton GJ,Courtois B,Price AH

更新日期：2009-06-22 00:00:00

abstract：:In 2009 the International Society for Computational Biology (ISCB) started to roll out regional bioinformatics conferences in Africa, Latin America and Asia. The open and competitive bid for the first meeting in Asia (ISCB-Asia) was awarded to Asia-Pacific Bioinformatics Network (APBioNet) which has been running the I...

journal_title：BMC genomics

authors： Schönbach C,Tan TW,Kelso J,Rost B,Nathan S,Ranganathan S

更新日期：2011-11-30 00:00:00

abstract：BACKGROUND:Macrobrachium rosenbergii, is one of a major freshwater prawn species cultured in Southeast Asia. White tail disease (WTD), caused by Macrobrachium rosenbergii nodavirus (MrNV), is a serious problem in farm cultivation and is responsible for up to 100% mortality in the post larvae stage. Molecular data on ho...

journal_title：BMC genomics

authors： Pasookhush P,Hindmarch C,Sithigorngul P,Longyant S,Bendena WG,Chaivisuthangkura P

更新日期：2019-10-22 00:00:00

abstract：BACKGROUND:The contribution of a gene to the fitness of a bacterium can be assayed by whether and to what degree the bacterium tolerates transposon insertions in that gene. We use this fact to compare the fitness of syntenic homologous genes among related Salmonella strains and thereby reveal differences not apparent a...

journal_title：BMC genomics

authors： Canals R,Xia XQ,Fronick C,Clifton SW,Ahmer BM,Andrews-Polymenis HL,Porwollik S,McClelland M

更新日期：2012-05-30 00:00:00

abstract：BACKGROUND:The pattern of point mutation is important for studying mutational mechanisms, genome evolution, and diseases. Previous studies of mutation direction were largely based on substitution data from a limited number of loci. To date, there is no genome-wide analysis of mutation direction or methylation-dependent...

journal_title：BMC genomics

authors： Jiang C,Zhao Z

更新日期：2006-12-13 00:00:00

abstract：BACKGROUND:The eyes and skin are obvious retinoid target organs. Vitamin A deficiency causes night blindness and retinoids are widely used to treat acne and psoriasis. However, more than 90% of total body retinol is stored in liver stellate cells. In addition, hepatocytes produce the largest amount of retinol binding p...

journal_title：BMC genomics

authors： He Y,Gong L,Fang Y,Zhan Q,Liu HX,Lu Y,Guo GL,Lehman-McKeeman L,Fang J,Wan YJ

更新日期：2013-08-28 00:00:00

abstract：BACKGROUND:Maintaining maximum genetic diversity and preserving breed viability in conserved populations necessitates the rigorous evaluation of conservation schemes. Three chicken breeds (Baier Yellow Chicken (BEC), Beijing You Chicken (BYC) and Langshan Chicken (LSC)) are currently in conservation programs in China. ...

journal_title：BMC genomics

authors： Zhang M,Han W,Tang H,Li G,Zhang M,Xu R,Liu Y,Yang T,Li W,Zou J,Wu K

更新日期：2018-08-09 00:00:00

abstract：BACKGROUND:Genetic admixture is a common caveat for genetic association analysis. Therefore, it is important to characterize the genetic structure of the population under study to control for this kind of potential bias. RESULTS:In this study we have sampled over 800 unrelated individuals from the population of Spain,...

journal_title：BMC genomics

authors： Gayán J,Galan JJ,González-Pérez A,Sáez ME,Martínez-Larrad MT,Zabena C,Rivero MC,Salinas A,Ramírez-Lorca R,Morón FJ,Royo JL,Moreno-Rey C,Velasco J,Carrasco JM,Molero E,Ochoa C,Ochoa MD,Gutiérrez M,Reina M,Pascual R,

更新日期：2010-05-25 00:00:00

abstract：:We describe an emerging initiative - the 'Functional Annotation of All Salmonid Genomes' (FAASG), which will leverage the extensive trait diversity that has evolved since a whole genome duplication event in the salmonid ancestor, to develop an integrative understanding of the functional genomic basis of phenotypic var...

journal_title：BMC genomics

authors： Macqueen DJ,Primmer CR,Houston RD,Nowak BF,Bernatchez L,Bergseth S,Davidson WS,Gallardo-Escárate C,Goldammer T,Guiguen Y,Iturra P,Kijas JW,Koop BF,Lien S,Maass A,Martin SAM,McGinnity P,Montecino M,Naish KA,Nichols K

更新日期：2017-06-27 00:00:00

abstract：BACKGROUND:After polyploidization, a genome may experience large-scale genome-repatterning, featuring wide-spread DNA rearrangement and loss, and often chromosome number reduction. Grasses share a common tetraploidization, after which the originally doubled chromosome numbers reduced to different chromosome numbers amo...

journal_title：BMC genomics

authors： Wang Z,Wang J,Pan Y,Lei T,Ge W,Wang L,Zhang L,Li Y,Zhao K,Liu T,Song X,Zhang J,Yu J,Hu J,Wang X

更新日期：2019-03-07 00:00:00

abstract：BACKGROUND:Restriction-modification (R-M) systems protect bacteria and archaea from attacks by bacteriophages and archaeal viruses. An R-M system specifically recognizes short sites in foreign DNA and cleaves it, while such sites in the host DNA are protected by methylation. Prokaryotic viruses have developed a number ...

journal_title：BMC genomics

authors： Rusinov IS,Ershova AS,Karyagina AS,Spirin SA,Alexeevski AV

更新日期：2018-12-07 00:00:00

abstract：BACKGROUND:Although an adverse early-life environment has been linked to an increased risk of developing the metabolic syndrome, the molecular mechanisms underlying altered disease susceptibility as well as their relevance to humans are largely unknown. Importantly, emerging evidence suggests that these effects operate...

journal_title：BMC genomics

authors： Emerald BS,Chng K,Masuda S,Sloboda DM,Vickers MH,Kambadur R,Gluckman PD

更新日期：2011-10-16 00:00:00

abstract：BACKGROUND:Protein phosphorylation is responsible for a large portion of the regulatory functions of eukaryotic cells. Although the list of sequenced genomes of filamentous fungi has grown rapidly, the kinomes of recently sequenced species have not yet been studied in detail. The objective of this study is to apply a c...

journal_title：BMC genomics

authors： Kosti I,Mandel-Gutfreund Y,Glaser F,Horwitz BA

更新日期：2010-02-24 00:00:00