Abstract:
Importance:Primary hyperparathyroidism (pHPT) is a common clinical entity, with approximately 100 000 new cases diagnosed each year in the United States. Most patients with pHPT have a relatively mild form of the disease and present with few if any overt signs or symptoms. This has led to a dilemma regarding which patients should be considered for parathyroid surgery. In this article, we review the established literature on the indications for surgery in asymptomatic pHPT and discuss the most recent consensus conference guidelines. Observations:The reviewed literature suggests that there were improved outcomes among patients with asymptomatic pHPT who underwent curative surgery. Conclusions and Relevance:Most patients with pHPT should be considered for parathyroidectomy. More randomized clinical trials are needed to strongly support a surgical recommendation for all asymptomatic patients with pHPT.
journal_name
JAMA Surgjournal_title
JAMA surgeryauthors
Stephen AE,Mannstadt M,Hodin RAdoi
10.1001/jamasurg.2017.1721subject
Has Abstractpub_date
2017-09-01 00:00:00pages
878-882issue
9eissn
2168-6254issn
2168-6262pii
2634515journal_volume
152pub_type
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