Abstract:
:Diurnal variations in ventricular tachyarrhythmias (VAs) have been demonstrated in idiopathic arrhythmogenic heart disease. The electrophysiological characteristics of diurnal variations in idiopathic right ventricular outflow tract (RVOT) VA have not previously been elucidated. Sixty-two consecutive patients undergoing catheter ablation for idiopathic RVOT VA (mean age: 42.8 ± 12.3 years, 35 females) were enrolled. The diurnal variation type (group 1, n = 36) was defined as those patients who had most ventricular premature contractions (VPCs) during the night hours by preprocedure Holter recordings. Group 2 (n = 26) was defined as those patients who did not have significant VPC variations. The baseline characteristics and electrophysiological properties were collected and analyzed, and the rates of recurrence after catheter ablation were compared between the 2 groups. In this study, heart rate variability analysis demonstrated lower low frequency/high frequency ratios in group 1 than in group 2 (3.95 ± 3.08 vs 6.26 ± 5.33; P = 0.042). There were no significant differences in baseline characteristics, echocardiography and electrophysiological characteristics between the 2 groups. During a mean follow-up period of 13.5 ± 11.0 months, a total of 16 patients had VA recurrences, including 13 patients from group 1 and 3 patients from group 2 (36.1% vs 12.5%, P = 0.039). This study demonstrated the effect of the autonomic nervous system in idiopathic RVOT VAs and that the diurnal variation type leads to a higher recurrence rate after catheter ablation.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Jhuo SJ,Lo LW,Chang SL,Lin YJ,Chung FP,Hu YF,Chao TF,Tuan TC,Liao JN,Lin CY,Chang YT,Lin CH,Walia R,Te ALD,Yamada S,Raharjo SB,Tang WH,Lee KT,Lai WT,Chen SAdoi
10.1097/MD.0000000000006516subject
Has Abstractpub_date
2017-04-01 00:00:00pages
e6516issue
15eissn
0025-7974issn
1536-5964pii
00005792-201704140-00013journal_volume
96pub_type
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