Ultra-high field MRI: Advancing systems neuroscience towards mesoscopic human brain function.

Abstract:

:Human MRI scanners at ultra-high magnetic field strengths of 7 T and higher are increasingly available to the neuroscience community. A key advantage brought by ultra-high field MRI is the possibility to increase the spatial resolution at which data is acquired, with little reduction in image quality. This opens a new set of opportunities for neuroscience, allowing investigators to map the human cortex at an unprecedented level of detail. In this review, we present recent work that capitalizes on the increased signal-to-noise ratio available at ultra-high field and discuss the theoretical advances with a focus on sensory and motor systems neuroscience. Further, we review research performed at sub-millimeter spatial resolution and discuss the limits and the potential of ultra-high field imaging for structural and functional imaging in human cortex. The increased spatial resolution achievable at ultra-high field has the potential to unveil the fundamental computations performed within a given cortical area, ultimately allowing the visualization of the mesoscopic organization of human cortex at the functional and structural level.

journal_name

Neuroimage

journal_title

NeuroImage

authors

Dumoulin SO,Fracasso A,van der Zwaag W,Siero JCW,Petridou N

doi

10.1016/j.neuroimage.2017.01.028

subject

Has Abstract

pub_date

2018-03-01 00:00:00

pages

345-357

eissn

1053-8119

issn

1095-9572

pii

S1053-8119(17)30028-9

journal_volume

168

pub_type

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