Abstract:
BACKGROUND:Differential diagnosis of hypokalemia and adrenocorticotropic hormone (ACTH)-dependent Cushing's syndrome often presents challenging in endocrinology and requires careful clinical, biochemical, radiological, and pathological investigations. Hypokalemia is a common abnormality and systematic approach is required to avoid delays in diagnosis of important underlying causes. CASE SUMMARY & CONCLUSION:A 49-year-old woman presented with moderate hypokalemia. Further evaluation showed hypercortisolism due to ectopic ACTH secretion.Chest computed tomography (CT) revealed a peripheral solitary pulmonary nodule. Excision biopsy of the nodule showed carcinoid tumor. After excision biopsy, all of the patient's symptoms improved and electrolytes and ACTH levels also became normal.Carciniod tumors should be considered as a differential diagnosis in patients presenting with hypokalemia and ectopic ACTH syndrome. Carcinoid tumor often present as solitary pulmonary nodule and excision biopsy can be curative.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Saeian S,Ghayumi SMA,Shams Mdoi
10.1097/MD.0000000000005046subject
Has Abstractpub_date
2016-12-01 00:00:00pages
e5046issue
50eissn
0025-7974issn
1536-5964pii
00005792-201612160-00002journal_volume
95pub_type
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