Abstract:
BACKGROUND:Addenbrooke's Cognitive Examination III (ACE-III) is a screening test that was recently validated for diagnosing dementia. Since it assesses attention, language, memory, fluency, and visuospatial function separately, it may also be useful for general neuropsychological assessments. The aim of this study was to analyze the tool's ability to detect early stages of Alzheimer's disease and to examine the correlation between ACE-III scores and scores on standardized neuropsychological tests. METHODS:Our study included 200 participants categorized as follows: 25 healthy controls, 48 individuals with subjective memory complaints, 47 patients with amnestic mild cognitive impairment and 47 mild Alzheimer's disease, and 33 patients with other neurodegenerative diseases. RESULTS:The ACE-III memory and language domains were highly correlated with the neuropsychological tests specific to those domains (Pearson correlation coefficient of 0.806 for total delayed recall on the Free and Cued Selective Reminding Test vs. 0.744 on the Boston Naming Test). ACE-III scores discriminated between controls and patients with amnestic mild cognitive impairment (AUC: 0.906), and between controls and patients with mild Alzheimer's disease (AUC: 0.978). CONCLUSION:Our results suggest that ACE-III is a useful neuropsychological test for assessing the cognitive domains of attention, language, memory, and visuospatial function. It also enables detection of Alzheimer's disease in early stages.
journal_name
Int Psychogeriatrjournal_title
International psychogeriatricsauthors
Matias-Guiu JA,Cortés-Martínez A,Valles-Salgado M,Rognoni T,Fernández-Matarrubia M,Moreno-Ramos T,Matías-Guiu Jdoi
10.1017/S1041610216001496subject
Has Abstractpub_date
2017-01-01 00:00:00pages
105-113issue
1eissn
1041-6102issn
1741-203Xpii
S1041610216001496journal_volume
29pub_type
杂志文章abstract:BACKGROUND:Capgras syndrome is characterized by the recurrent, transient belief that a person has been replaced by an identical imposter. We reviewed clinical characteristics of Dementia with Lewy Bodies (DLB) patients with Capgras syndrome compared to those without Capgras. METHODS:We identified 55 consecutive DLB pa...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002189
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:The ability to manage everyday technology (ET), such as computers and microwave ovens, is increasingly required in the performance of everyday activities and participation in society. This study aimed to identify aspects that influence the ability to manage ET among older adults with and without cognitive im...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211002092
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:We studied the suitability of The Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Battery (CERAD-NB) total score for monitoring Alzheimer's disease (AD) progression in early-diagnosed medicated patients. We also investigated possible differences in progression between patients w...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213000653
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:In a previous paper, we presented results from a 12-week study of a Psychomotor DANCe Therapy INtervention (DANCIN) based on Danzón Latin Ballroom that involves motor, emotional-affective, and cognitive domains, using a multiple-baseline single-case design in three care homes. This paper reports the results ...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S104161021600171X
更新日期:2017-02-01 00:00:00
abstract::ABSTRACTBackground:Research reviews highlight methodological limitations and gaps in the evidence base for the arts in dementia care. In response, we developed a 12-week visual art program and evaluated the impact on people living with dementia through a mixed-methods longitudinal investigation. METHODS:One hundred a...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002162
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:The purpose of the study was to examine the attention deficit hyperactivity disorder (ADHD) symptomatology across the lifespan by comparing older individuals' self-reports about current ADHD symptoms and symptoms in childhood. METHODS:The 25-item Wender Utah Rating Scale (WURS) was initially administered in...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002050
更新日期:2013-04-01 00:00:00
abstract::An extensive new caring program--including the introduction of Individual Care Plans and changes in ward organization, caring techniques, and caring philosophy--was introduced at two psychogeriatric wards with severely demented patients. The hypotheses were that the patients (n = 31) would improve in psychosocial capa...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610293001504
更新日期:1993-10-01 00:00:00
abstract:BACKGROUND:A carer-held record (CHR) was developed to enable carers to contribute to care plans for their relatives with dementia, alongside other professionals. The aim of this study was to establish whether CHRs provide any measurable benefits for carers, in the areas of health, stress, knowledge of dementia and locu...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610205002565
更新日期:2006-06-01 00:00:00
abstract::Over the past five to ten years, neuroimaging capability for neurodegenerative diseases has made remarkable progress. However, debate remains as to the true clinical utility of these advanced and costly investigations. Not only is the place of these tests in diagnostic algorithms unclear, but the access to them varies...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/S1041610211000901
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Inability to walk compromises the well-being of the growing number of nursing home residents with dementia. The purpose of this study was to estimate the incidence and identify predictors of walking disability that may be remediable. METHODS:A cohort was followed fortnightly for a year in 15 nursing homes i...
journal_title:International psychogeriatrics
pub_type: 杂志文章,多中心研究
doi:10.1017/S1041610210000116
更新日期:2011-02-01 00:00:00
abstract::This paper provides a review of research issues and findings on the epidemiology of delirium. Despite the fact that research on this important geriatric syndrome has been conducted for many decades, several methodological issues make it difficult to compare findings across studies. In this paper we first discuss broad...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/s1041610291000625
更新日期:1991-01-01 00:00:00
abstract:UNLABELLED:This article reports the findings of a 3-year epidemiological survey for dementia in an urban community-resident population in Mumbai (Bombay), India, wherein the prevalence of all types of dementia was determined. METHOD:The study was conducted in three stages. Stage 1: From a potential pool of 30,000 subj...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610201007852
更新日期:2001-12-01 00:00:00
abstract::ABSTRACTObjectives:The objectives of the study were to examine the trajectory of spirituality among older adults, to investigate the roles of gender and religion on the developmental trajectory of spirituality, and to explore whether the linear growth of spirituality accelerated or decelerated at time points at which ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000029
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The economic cost of dementia is high and can be predicted by cognitive and neuropsychiatric profiles. The differential costs of the various subtypes of dementia are unknown in Argentina, and this study therefore aimed to compare these costs. METHODS:Patients with a diagnosis of dementia of Alzheimer-type (...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210002012
更新日期:2011-05-01 00:00:00
abstract::ABSTRACTBackground:Evidence suggests that semantic interference may be a sensitive indicator of early dementia. We examined the utility of the Semantic Interference Test (SIT), a cognitive stress memory paradigm which taps proactive and retroactive semantic interference, for predicting progression from mild cognitive ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002666
更新日期:2018-10-01 00:00:00
abstract::The authors conducted a survey of members of the International Psychogeriatric Association (IPA) to determine the state of development of both the profession of geriatric psychiatry and services for mentally ill elderly. Ratings for both issues were based on a scale of 1 to 4, with 1 being little to no development and...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610298005444
更新日期:1998-12-01 00:00:00
abstract:BACKGROUND:Effectiveness of educational interventions targeted at improving delirium care is limited by implementation barriers. Studying factors which shape learning needs can overcome these knowledge transfer barriers. This in-depth qualitative study explores learning needs of hospital staff relating to care needs of...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212002074
更新日期:2013-04-01 00:00:00
abstract:BACKGROUND:It is unclear how brain reserve interacts with gender and apolipoprotein E4 (APOE4) genotype, and how this influences the progression of Alzheimer's disease (AD). The association between intracranial volume (ICV) and progression to AD in subjects with mild cognitive impairment (MCI), and differences accordin...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021500229X
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:This study aimed to determine: (1) the prevalence of depression, anxiety, and depression associated with anxiety (DA); (2) the risk factor profile of depression, anxiety, and DA; (3) the course of depression, anxiety, and DA over 24 months. METHODS:Two-year longitudinal study of 20,036 adults aged 60+ years...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S104161021200107X
更新日期:2012-10-01 00:00:00
abstract::I read with great interest the study of Petrazzuoli et al. (2017) on exploring dementia management attitudes in primary care. The authors made a laudable effort to evaluate this important issue, which certainly needs timely attention. The high response rate from 25 member countries of the European General Practice Res...
journal_title:International psychogeriatrics
pub_type: 评论,信件
doi:10.1017/S1041610217003003
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Despite the increasing prevalence of Alzheimer's disease (AD), very few studies have examined advanced preparation for the possibility of becoming sick with AD, and these few studies indicate a general lack of preparation. This study aimed to expand knowledge regarding preparedness for AD among younger and o...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610211001803
更新日期:2012-02-01 00:00:00
abstract::ABSTRACTBackground:The number of elderly individuals living in China is increasing rapidly. The aim of this study was to examine the potential risk factors of geriatric depression in rural areas. METHODS:A repeated cross-sectional study was conducted between January 2015 and October 2016 in rural China. Nine hundred ...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610218000030
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Although interpersonal interactions are thought to affect psychopathology in schizophrenia, there is a paucity of data about how older adults with schizophrenia manage interpersonal conflicts. This paper examines interpersonal conflict strategies and their impact on positive symptom remission in older adults...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610212001093
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Research on the behavioral correlates of anxiety in older adults is sparse. The aim of this study was to explore the association of anxiety with behavioral patterns defined by health, activity, emotional and social variables. METHODS:A convenience sample of 395 older adults completed measures of health, act...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610214001148
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:Hospital-treated deliberate self harm and suicide among older adults have rarely been examined at a national level. METHODS:The Irish Central Statistics Office provided suicide and undetermined death data for 1980-2006. The National Registry of Deliberate Self Harm collected data relating to deliberate self...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610210001377
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Children of patients with young onset dementia (YOD) who are confronted with a parent who has a progressive disease, often assist in caregiving tasks, which may have a great impact on their lives. The objective of the present study is to explore the experiences of children living with a young parent with dem...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610213001890
更新日期:2014-12-01 00:00:00
abstract:OBJECTIVE:Clinical syndromes such as amnestic mild cognitive impairment (MCI) are highly predictive of future development of Alzheimer's disease (AD), but it is not known how many of the individuals that develop the disease can be identified with these syndromes. This study aims to determine how many individuals with A...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610207006564
更新日期:2008-04-01 00:00:00
abstract:BACKGROUND:Delirium is frequently observed in clinical practice, particularly in medical and surgical wards and more so among patients at risk, especially elderly with preexisting central nervous system impairments. OBJECTIVE:Despite the severe consequences of delirium, epidemiological data relating to incidence of de...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/s1041610202008499
更新日期:2002-09-01 00:00:00
abstract::ABSTRACTBackground:The aim of this study is to identify the prevalence and risk factors of documented delirium in general practices in Germany. METHODS:The present study includes 2,194 patients over the age of 65 years with delirium and 2,194 controls without delirium from a sample of 6,180,042 patients from 1,262 ge...
journal_title:International psychogeriatrics
pub_type: 杂志文章
doi:10.1017/S1041610217002587
更新日期:2018-04-01 00:00:00
abstract::In this review, we explore the relationship between epilepsy and cognition and between epilepsy and dementia. Chronic epilepsy, particularly mesial temporal lobe epilepsy (MTLE) with hippocampal sclerosis, may be associated with impaired cognition, which can be secondary to uncontrolled seizures, to adverse effects of...
journal_title:International psychogeriatrics
pub_type: 杂志文章,评审
doi:10.1017/s1041610205002024
更新日期:2005-01-01 00:00:00