Abstract:
:The effect of intracranial internal carotid artery (ICA) calcification on cognitive impairment is uncertain. Our objective was to investigate whether intracranial ICA calcification is a significant cognitive predictor for cognitive impairment. Global cognition and degrees of intracranial ICA calcification of 579 subjects were assessed with Mini-Mental State Examination (MMSE) and Agatston calcium scoring method, respectively. Other risk factors for cognitive impairment, including age, education level, hypertension, diabetes mellitus, smoking, hyperlipidemia, and body mass index, were documented and analyzed for their associations with cognitive function. In univariate analyses, older age, lower education level, hypertension, diabetes mellitus, and higher intracranial ICA Agatston scores were significantly associated with cognitive impairment. In ordinal logistic regression, only age and total intracranial ICA Agatston score were significant risk factors for cognitive impairment. After adjustment for the other documented risk factors, subjects were 7% (95% CI: 5-10; P < 0.001) and 6% (95% CI: 0-13; P = 0.04) more likely to have lower cognitive category with every year increment of age and every 100-point increment of the total intracranial ICA Agatston score respectively. These results suggest an important role of the intracranial ICA calcification on cognitive impairment.
journal_name
Medicine (Baltimore)journal_title
Medicineauthors
Kao HW,Liou M,Chung HW,Liu HS,Tsai PH,Chiang SW,Chou MC,Peng GS,Huang GS,Hsu HH,Chen CYdoi
10.1097/MD.0000000000001546subject
Has Abstractpub_date
2015-09-01 00:00:00pages
e1546issue
39eissn
0025-7974issn
1536-5964pii
00005792-201509050-00019journal_volume
94pub_type
杂志文章相关文献
MEDICINE文献大全abstract::The Pediatric HIV/AIDS Cohort Study (PHACS), the largest ongoing longitudinal study of perinatal HIV-infected (PHIV) and HIV-exposed, uninfected (PHEU) children in the United States, comprises the Surveillance Monitoring of Antiretroviral Therapy [ART] Toxicities (SMARTT) Study in PHEU children and the Adolescent Mast...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000004733
更新日期:2016-09-01 00:00:00
abstract:BACKGROUND:Peripherally inserted central catheter (PICC) is closely related to venous thromboembolism (VTE). It is a common complication of hospitalized patients, and its etiology is complex. How to prevent the occurrence of VTE is the focus of clinical work. In order to provide basis for individual prevention and accu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000023091
更新日期:2020-11-06 00:00:00
abstract::Transient global amnesia is now considered a very rare complication of cerebral angiography. Various etiological mechanisms have been suggested to account for this complication, but no consensus has been reached yet. This case report documents one of the few reported cases of cerebral angiography-related transient glo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003590
更新日期:2016-05-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002212.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000480961.17450.a6
更新日期:2016-02-12 00:00:00
abstract::We present 2 rare cases of patients with uncontrolled hemorrhagic shock induced by traumatic ascending aortic pseudoaneurysm rupture into the esophagus. Two men were presented to the hospital after traffic accidents. Their chest radiograph showed no obvious signs of aortic damage or aortic pseudoaneurysms but only a s...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000000716
更新日期:2015-04-01 00:00:00
abstract:RATIONALE:Foreign-body ingestion is a common phenomenon and foreign bodies are mostly excreted in stool. Once sharp bodies are ingested without being realized, perforation of intestine is possible and misdiagnosis may be made. We report 2 toothpick ingestion cases that were both diagnosed accurately. PATIENT CONCERNS:...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009710
更新日期:2018-02-01 00:00:00
abstract:BACKGROUND:Optic atrophy (OPA) is a very tricky disorder. Presently, no effective management is available for this condition. Previous studies have reported that acupuncture may be effective for the treatment of OPA. However, its effectiveness is still inconclusive. Thus, this study will aim to assess the effectiveness...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016879
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:The process of population aging inclines to seek determinants of the quality of life in the older people. Health self-assessment is the one of the main elements of the quality of life. In the older people it is associated with functional efficiency. The aim of the study was to determine correlations of physi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000015984
更新日期:2019-06-01 00:00:00
abstract:RATIONALE:The superior sagittal sinus (SSS) and transverse sinus are the major dural sinuses that receive a considerable amount of venous drainage. The occlusion of them has been suggested to cause intracranial hypertension, hemorrhage, and lead to potentially fatal consequences. PATIENT CONCERNS:We reported a 35-year...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009038
更新日期:2017-12-01 00:00:00
abstract::Globalization has attracted much attention to universities over the past decade. The aim of this study was to evaluate the effect of the United States-China international pharmacy education programs (IPEP) in China.Kirkpatrick's model of evaluation was used to evaluate IPEP from reaction and learning levels. In the re...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020945
更新日期:2020-07-02 00:00:00
abstract:INTRODUCTION:The Klippel-Trenaunay syndrome (KTS) is a rare congenital disorder. The obstetric course of women with KTS varies. Complications include bleeding, disseminated intravascular coagulation (DIC), thromboembolic events, etc. PATIENT CONCERNS:: Here, we report a case of late puerperal hemorrhage of a Chinese pu...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018378
更新日期:2019-12-01 00:00:00
abstract::Aberrant glycosylated IgA1 molecules, mainly galactose-deficient IgA1 (Gd-IgA1), are important causal factors in IgA nephropathy; however, the underlying mechanism for the production of aberrantly glycosylated IgA1 is unknown. A recent genome-wide association study identified a novel IgAN susceptibility gene, TNFSF13,...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003099
更新日期:2016-03-01 00:00:00
abstract:RATIONALE:Late complement deficiency increases susceptibility to meningococcal disease and recurrent infections. In Korea, 5 case reports have described meningococcal disease with complement deficiency. However, C6 deficiency has not been described previously. PATIENT CONCERNS:A 21-year-old police trainee presented wi...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000020362
更新日期:2020-05-22 00:00:00
abstract:RATIONALE:Secondary hyperparathyroidism (SHPT) is often complicated with chronic renal failure. Though the total parathyroidectomy (TPTX) with forearm autotransplantation (FAT) has been commonly used to treatment refractory renal SHPT, the recurrence of SHPT is not infrequent, resulting from hyperplastic autograft, rem...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000016077
更新日期:2019-06-01 00:00:00
abstract::[This corrects the article DOI: 10.1097/MD.0000000000002325.]. ...
journal_title:Medicine
pub_type: 已发布勘误
doi:10.1097/01.md.0000483155.73927.6c
更新日期:2016-05-06 00:00:00
abstract::The refinement in surgical techniques combined with the preoperative management has improved the resectability rate of perihilar cholangiocarcinoma (pCCA). However, the prognosis of pCCA with curative resection is still dismal. This meta-analysis was performed to investigate the prognostic clinicopathological factors ...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000011999
更新日期:2018-08-01 00:00:00
abstract::Homeless people are particularly exposed to ectoparasites, but their exposure to arthropod-borne diseases has not been evaluated systematically. A medical team of 27 persons (7 nurses, 6 infectious disease residents or fellows, 2 dermatologists, and 12 infectious disease specialists) visited the 2 shelters in Marseill...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/01.md.0000152373.07500.6e
更新日期:2005-01-01 00:00:00
abstract::End stage renal disease (ESRD) has been reported to be an important risk factor for systemic vascular disease. Retinal vein occlusion (RVO) is closely related with cardiovascular diseases; however, its association with ESRD had not been reported. The aim of the study was to investigate whether ESRD is a risk factor fo...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000001960
更新日期:2015-11-01 00:00:00
abstract::Nuclear factor-κB-inducing kinase (NIK) is a new regulator of nuclear factor-κB signaling, which plays an important role in tumorigenesis. This study aimed to examine the expression of NIK in gastric cancer and investigate its clinical significance.Tumor issues were collected from 80 gastric cancer patients who receiv...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000018864
更新日期:2020-01-01 00:00:00
abstract:RATIONALE:Arterial occlusion, a rare condition after total knee arthroplasty (TKA), may cause fatal outcomes if not treated on time. We report a case of arterial occlusion after undergoing navigated TKA with no tourniquet use, in a patient at high risk of postoperative arterial occlusion due to the patient's ipsilatera...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012719
更新日期:2018-10-01 00:00:00
abstract:RATIONALE:Woven coronary artery is an extremely unusual congenital anomaly with unknown etiology. Because of normal flow after anomalous segment, this anomaly is considered to be benign. PATIENT CONCERNS:A 51-year-old man was admitted to our hospital with exertional dyspnea that he had experienced for half a year. Wov...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000008302
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:The argument on the recommended rehabilitation protocol following arthroscopic rotator cuff repair remains to be resolved. So this meta-analysis was presented to evaluate the differences of clinical effects between the 2 distinct rehabilitation protocols after arthroscopic rotator cuff repair. METHODS:The P...
journal_title:Medicine
pub_type: 杂志文章,meta分析,评审
doi:10.1097/MD.0000000000009625
更新日期:2018-01-01 00:00:00
abstract:RATIONALE:Primary pulmonary meningiomas are extremely rare, and only a few cases have been reported in the medical literature. Imaging findings of primary pulmonary meningiomas have been reported even more rarely. PATIENT CONCERNS:We present the case of a 54-year-old male patient with cough and sputum lasting for 20 y...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000009651
更新日期:2018-01-01 00:00:00
abstract::Identification of meaningful cluster modules of differential genes or representative biomarkers related to the stages of ovarian cancer (OC) is pivotal, which may help to detect mechanisms of OC progression and evaluate OC patients' prognosis.We downloaded gene expression data and the corresponding clinical informatio...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000011895
更新日期:2018-08-01 00:00:00
abstract::Prior evidence suggested that inflammation and inflammatory cytokines polymorphisms might be essential in the development of coronary heart disease (CHD) and cognitive decline. The following study investigated the associations between interleukin-35 (IL-35) polymorphisms and cognitive decline in CHD patients over a 2-...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000021390
更新日期:2020-07-31 00:00:00
abstract:BACKGROUND:Urticaria is a common skin disease that has a high impact on a patient's daily life. Xiaofeng powder (XFP) is one of the most commonly used Chinese herbal formula in China for urticaria. However, due to the lack of systematic evaluations, its clinical efficacy remains controversial. This meta-analysis was pe...
journal_title:Medicine
pub_type: 杂志文章,meta分析
doi:10.1097/MD.0000000000013039
更新日期:2018-11-01 00:00:00
abstract::Preoperative identification of individual sensitivity to opioid analgesics could improve the quality of postoperative analgesia. We explored the feasibility and utility of a real-time assessment of sufentanil sensitivity in predicting postoperative analgesic requirement.Our primary study included 111 patients who unde...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000003915
更新日期:2016-06-01 00:00:00
abstract:RATIONALE:The emphysematous prostatic abscess is a rare but potentially life-threatening clinical condition. The early diagnosis is difficult due to nonspecific symptoms. PATIENT CONCERNS:A 72-year-old man with poorly controlled diabetes mellitus was admitted to hospital because of dysuria and acute urine retention. H...
journal_title:Medicine
pub_type: 杂志文章,评审
doi:10.1097/MD.0000000000019391
更新日期:2020-02-01 00:00:00
abstract::The aim of the study was to assess the independent contribution of hyperuricemia to coronary artery disease (CAD) confirmed by coronary angiography (CAG), and to explore associations between serum uric acid (SUA) level and CAD.We performed a retrospective cohort study of 5069 patients who underwent CAG. Patients were ...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000012926
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Cerebral aneurysm surgery has significant mortality and morbidity rate. Inflammation plays a key role in the pathogenesis of intracranial aneurysms, their rupture, subarachnoid hemorrhage and neurologic complications. Proinflammatory cytokine level in blood and cerebrospinal fluid (CSF) is an indicator of in...
journal_title:Medicine
pub_type: 杂志文章
doi:10.1097/MD.0000000000017450
更新日期:2019-10-01 00:00:00