Abstract:
:Toxic epidermal necrolysis is a rare but often fatal hypersensitivity reaction to numerous agents, including most anticonvulsants. The authors present a case of fatal phenytoin-related toxic epidermal necrolysis in a patient who was given prophylactic anticonvulsant therapy after he sustained a moderately severe closed head injury. The typical course and current management of toxic epidermal necrolysis are reviewed, as are the indications for the prophylaxis of posttraumatic epilepsy.
journal_name
Neurosurgeryjournal_title
Neurosurgeryauthors
Kelly DF,Hope DGdoi
10.1097/00006123-198912000-00022subject
Has Abstractpub_date
1989-12-01 00:00:00pages
976-8issue
6eissn
0148-396Xissn
1524-4040journal_volume
25pub_type
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