Abstract:
:A cohort of 6168 schizophrenic patients was followed from 1957 to 1984 to determine the incidence of cancer in these patients. In the male schizophrenic patients the incidence of cancer was found to be significantly reduced in comparison with the general Danish population. This reduction was especially marked for cancer in the respiratory system, cancer of the prostate and cancer of the bladder. In the female patients the overall incidence of cancer did not differ from that of the general Danish population, but there was an increased risk of cancer of the digestive tract, especially cancer of the pancreas and a slight increase of the risk of breast cancer. In the female patients the risk of respiratory cancers and cancer of the female genital organs, especially cancer of the uterine cervix, was reduced. These alterations of the incidence of cancer in schizophrenic patients cannot be ascribed to differences in diagnostic accuracy. As a possible explanation of these findings a reduced exposure to well known carcinogens such as cigarette smoke may be relevant. We speculate that exposure to neuroleptics such as phenothiazines and reserpine may also be part of the explanation for the findings.
journal_name
J Epidemiol Community Healthjournal_title
Journal of epidemiology and community healthauthors
Mortensen PBdoi
10.1136/jech.43.1.43subject
Has Abstractpub_date
1989-03-01 00:00:00pages
43-7issue
1eissn
0143-005Xissn
1470-2738journal_volume
43pub_type
杂志文章abstract:BACKGROUND:In the UK, overall stroke mortality has declined. A similar trend has been seen in coronary heart disease, although recent reports suggest this decline might be levelling off in middle-aged adults. AIM:To investigate recent trends in stroke mortality among those aged 40-69 years in England. METHODS:The aut...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.086785
更新日期:2010-06-01 00:00:00
abstract::Prompted by my participation in the People's Climate March held in New York City on 21 September 2014, as part of the 'Harvard Divest' contingent, in this brief essay I reflect on the late 20th century development of--and debates over--the necessity of ecological thinking in epidemiology, and also the still limited en...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-205027
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:The evidence on mortality patterns by education in Spain comes from regional areas. This study aimed to estimate these patterns in the whole Spanish population. METHODS:All citizens aged 25 years and over and residing in Spain in 2001 were followed during 7 years to determine their vital status, resulting i...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2014-204186
更新日期:2014-12-01 00:00:00
abstract:STUDY OBJECTIVE:To compare health walks, a community based lay-led walking scheme versus advice only on physical activity and cardiovascular health status in middle aged adults. DESIGN:Randomised controlled trial with one year follow up. Physical activity was measured by questionnaire. Other measures included attitude...
journal_title:Journal of epidemiology and community health
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/jech.56.4.246
更新日期:2002-04-01 00:00:00
abstract:BACKGROUND:Most existing studies on maternal employment and childhood overweight/obesity are from the USA. They are predominantly cross-sectional and show a consistent linear association between the two. Less is known about the joint impact of fathers' and mothers' work hours on childhood overweight and obesity. OBJEC...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2018-211132
更新日期:2019-08-01 00:00:00
abstract::The feasibility of conducting postmarketing drug surveillance by record linkage in Tayside was assessed. The key feature of the method is that all hospital discharge data are already computerised by the area health board and may be accessed through the unique community health number (CHNo) which has been allocated to ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.38.3.226
更新日期:1984-09-01 00:00:00
abstract:BACKGROUND:Tobacco smoke pollution (TSP) has major negative effects on infant health. Our objectives were to determine the effectiveness of a brief primary care intervention directed at parents who smoke in reducing babies' TSP exposure, and to establish variables related to greater exposure. METHOD:A multicentre, ope...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1136/jech-2014-204708
更新日期:2015-03-01 00:00:00
abstract:BACKGROUND:Identifying children at risk of poor developmental outcomes remains a challenge, but is important for better targeting children who may benefit from additional support. We explored whether data routinely collected in early life predict which children will have language disability, overweight/obesity or behav...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2018-211028
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Previous studies show contradictory findings on the relationship between health and intergenerational living arrangements (ILAs), which may be due to variation in who selects themselves into and out of ILA. Addressing the selectivity into ILA and the health of the older generation, we assess whether there is...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2017-209896
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:In the article by Starfield and colleagues, it was suggested that the concept of prevention has gone astray. This article aims to extend their ideas. METHODS:Our methods are to take the Starfield et al article and argue that it is possible and useful to see prevention in a wider context, going beyond preven...
journal_title:Journal of epidemiology and community health
pub_type: 评论,杂志文章
doi:10.1136/jech.2008.082818
更新日期:2011-02-01 00:00:00
abstract::Birthweight and gestational age are the two most commonly used continuous variables in perinatal research. Dichotomous outcomes derived from these two variables include low birthweight, preterm birth and small for gestational age, each extensively used as perinatal and population health indicators within public health...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2011-200772
更新日期:2012-11-01 00:00:00
abstract:OBJECTIVE:To examine material and behavioural factors as explanations for occupational class differences in health, while taking into account the interrelations between these two groups of factors. METHODS:Data from cross sectional surveys among middle aged women and men employed by the City of Helsinki (n = 6062, res...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2003.019323
更新日期:2005-02-01 00:00:00
abstract:BACKGROUND:Cancer screening in the USA is suboptimal, particularly for individuals living in vulnerable communities. This study aimed to understand how rurality and racial segregation are independently and interactively associated with cancer screening and cancer fatalism. METHODS:We used data from a nationally repres...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2019-212425
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:Many youth deaths occur in the first year of life, from prematurity and anomalies. Detailing mortality after age 1 year may differentially guide preventive strategies in children, adolescents and young adults. METHODS:A cohort study in Ontario, Canada comprised 3 139 698 children born from 1990 to 2016. Adj...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2019-213365
更新日期:2020-03-01 00:00:00
abstract:OBJECTIVE:To compare a self administered computerised assessment of neurotic psychiatric disorder (psychiatric morbidity) with an identical assessment administered by a human interviewer. In particular, to discover whether a computerised assessment overestimates or underestimates the prevalence of psychiatric morbidity...
journal_title:Journal of epidemiology and community health
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1136/jech.48.2.207
更新日期:1994-04-01 00:00:00
abstract::The following essay outlines the intervention and presents a framework that will serve as a guide in the evaluation of the different effects of the Superblocks. Superblocks consist of amalgamations of blocks throughout the city, with the goal of improving the habitability of public spaces, advancing sustainable mobili...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,评审
doi:10.1136/jech-2018-211738
更新日期:2019-07-01 00:00:00
abstract:BACKGROUND:While various measures of common mental disorders (CMD) have been found to be associated with mortality, a comparison of how different measures predict mortality may improve our understanding of the association. This paper compares how the Hospital Anxiety and Depression Scale (HADS) and the 30-item General ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2012-201927
更新日期:2013-07-01 00:00:00
abstract:BACKGROUND:Inconsistent results have been found on the association between air pollution and stroke mortality. Additionally, evidence on people who are potentially sensitive to air pollution-associated stroke mortality is limited. METHODS:Daily stroke mortality of adults aged over 65 between 2003 and 2008 in Shanghai,...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech-2012-201096
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:The Wales National Exercise Referral Scheme (NERS) is a 16-week programme including motivational interviewing, goal setting and relapse prevention. METHOD:A pragmatic randomised controlled trial with nested economic evaluation of 2160 inactive participants with coronary heart disease risk (CHD, 1559, 72%), ...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,随机对照试验
doi:10.1136/jech-2011-200689
更新日期:2012-08-01 00:00:00
abstract:OBJECTIVES:To examine the relationship between residential change and a woman's subsequent risk of intimate partner violence (IPV), whether by a past or a new offender, a relationship that has not been prospectively examined to date. DESIGN:A dynamic cohort of women who recently changed residence (movers) was compared...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2006.047084
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:Housing is an important environmental influence on population health, and there is growing evidence of health effects from indoor environment characteristics such as low indoor temperatures. However, there is relatively little research, and thus little firm guidance, on the cost-effectiveness of public polic...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,随机对照试验
doi:10.1136/jech.2007.070037
更新日期:2009-04-01 00:00:00
abstract:OBJECTIVE:To assess comprehensively the validity of the data in the Finnish Medical Birth Registry (MBR) by the combined use of several controls and internal analysis of the data. DESIGN:The MBR data were individually linked to a medical record sample (n = 775) and to all perinatal death certificates in 1987. The data...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.47.3.242
更新日期:1993-06-01 00:00:00
abstract:STUDY OBJECTIVE:Knowledge about changes in wellbeing during the passage from professional studies to working life is scarce and controversial. This study examined these changes among university graduates with good and poor employment prospects. DESIGN:A longitudinal study with four postal questionnaire surveys of a cl...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.55.11.831
更新日期:2001-11-01 00:00:00
abstract:STUDY OBJECTIVE:To explore individual and social factors that could predict health care utilisation and medication among people with chronic pain in an unselected population. DESIGN:A mailed survey with questions about pain and mental symptoms, disability, self care action, visits to health care providers, and medicat...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.53.8.503
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:In observational studies, mainly from Western Caucasian populations, moderate alcohol use has been shown to be associated with a lower risk of diabetes. However, whether the protection is due to the attributes of alcohol or to those of moderate alcohol users is difficult to disentangle. A population with a d...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章,多中心研究
doi:10.1136/jech.2008.077602
更新日期:2009-02-01 00:00:00
abstract:BACKGROUND:Low socioeconomic status (SES) has been linked to increased risk of hypertension, a known risk factor for cardiovascular disease. How the risk is altered by intergenerational social mobility is not well known. The aim of this study is to investigate parental SES, adult SES and the intergenerational social mo...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2010.130567
更新日期:2012-06-01 00:00:00
abstract::Infant mortality rates vary from area to area. Part of this variation is due to the socioeconomic characteristics of the area and part to other factors including the obstetric, paediatric, and community health services. Four social indicators associated with infant deaths are used to control for some of the variations...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.36.1.11
更新日期:1982-03-01 00:00:00
abstract::More than 30 years ago, the older of us published a paper with the proposal that all scientific papers should start with a statement along the lines of: "These are the opinions on which I base my facts". Why pretend? To take a topical example, if you are on the nature side of the nature/nurture debates, is it likely t...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2008.081695
更新日期:2008-12-01 00:00:00
abstract:BACKGROUND:Research has demonstrated associations between smoking and reading skills, but other literacy skills such as speaking, listening and numeracy are less studied despite our dependence on the use of numbers and the oral exchange to deliver information on the risks of smoking. METHODS:The authors used multivari...
journal_title:Journal of epidemiology and community health
pub_type: 杂志文章
doi:10.1136/jech.2011.136341
更新日期:2012-02-01 00:00:00
abstract::England was the first European country to pursue a systematic policy to reduce socio-economic inequalities in health. This paper assesses whether this strategy has worked, and what lessons can be learnt. A review of documents was conducted, as well as an analysis of entry-points chosen, specific policies chosen, imple...
journal_title:Journal of epidemiology and community health
pub_type: 历史文章,杂志文章
doi:10.1136/jech.2010.128280
更新日期:2011-07-01 00:00:00