Disconnected pancreatic duct syndrome: disease classification and management strategies.

Abstract:

BACKGROUND:Disconnected pancreatic duct syndrome (DPDS) typically complicates acute necrotizing pancreatitis (ANP) and presents as a pseudocyst months after the initial episode of pancreatitis. However, our experience suggests that the presentation of DPDS may be quite varied and might require significant evaluation and judgment before surgical intervention. We sought to determine the presentations of DPDS and assess the management of the various forms of presentation. STUDY DESIGN:A retrospective review of all patients with DPDS between July 2005 and June 2011 was performed. Patients were included when CT scan demonstrated a clear disconnected pancreas that was confirmed at operation. Medical records were reviewed in detail to determine clinical presentation, management, and outcomes. RESULTS:Of the 50 patients identified, 66% were male, with a mean age of 53 ± 16 years. Mortality was 2% and 3 patients (6%) required late reoperation. The DPDS presented in 3 forms: diagnosed concurrently with ANP (concurrent DPDS; n = 28); delayed presentation with a pseudocyst (delayed DPDS; n = 15); and as a consequence of chronic pancreatitis (CP) (CP DPDS; n = 7). Concurrent DPDS was treated with necrosectomy including body/tail resection within 60 days of onset and complicated by a grade B/C fistula in 36%. Delayed DPDS required distal pancreatectomy 440 days after diagnosis, with a 7% fistula rate. Chronic pancreatitis DPDS was treated with lateral pancreatojejunostomy at 417 days with no fistulas. CONCLUSIONS:Disconnected pancreatic duct syndrome presents concurrently with ANP, in a delayed fashion, or infrequently in the setting of CP. Prompt recognition and classification with appropriate operative therapy results in low mortality and nonoperatively managed pancreatic fistulas.

journal_name

J Am Coll Surg

authors

Fischer TD,Gutman DS,Hughes SJ,Trevino JG,Behrns KE

doi

10.1016/j.jamcollsurg.2014.03.055

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

704-12

issue

4

eissn

1072-7515

issn

1879-1190

pii

S1072-7515(14)00409-8

journal_volume

219

pub_type

杂志文章
  • Laparoscopic liver resection: an examination of our first 300 patients.

    abstract:BACKGROUND:Laparoscopic liver resection is a procedure in evolution. In the last decade it has evolved from a novel procedure to a standard part of the hepatic surgeon's armamentarium. Few data exist on the development of a laparoscopic resection program. STUDY DESIGN:With IRB approval, a retrospective review of 300 c...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.04.032

    authors: Cannon RM,Brock GN,Marvin MR,Buell JF

    更新日期:2011-10-01 00:00:00

  • Consequences of targeted parathyroidectomy guided by localization studies without intraoperative parathyroid hormone monitoring.

    abstract:BACKGROUND:After excision of an abnormal gland, the dynamics of intraoperative parathyroid hormone (PTH) levels signal whether or not more hypersecreting tissue is present. This quantitative assurance of operative success has led to targeted exploration of the hyperfunctioning gland(s). Some have questioned the need fo...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2006.02.003

    authors: Carneiro-Pla DM,Solorzano CC,Irvin GL 3rd

    更新日期:2006-05-01 00:00:00

  • Results of curative gastrectomy for carcinoma.

    abstract:BACKGROUND:In the western literature, controversy exists regarding the operative management of carcinoma of the stomach. Still debated are the extent of gastric resection, the role of splenectomy, and the significance of lymphadenectomy. STUDY DESIGN:We performed a retrospective study of 646 consecutive patients who u...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Stipa S,Di Giorgio A,Ferri M,Botti C

    更新日期:1994-11-01 00:00:00

  • Who are our future surgeons? Characteristics of medical school graduates planning surgical careers: analysis of the 1997 to 2004 Association of American Medical Colleges' Graduation Questionnaire National Database.

    abstract:BACKGROUND:Identification of correlates of contemporary US medical graduates' surgical career plans can provide insights about the emerging surgical workforce composition and inform future recruitment efforts. STUDY DESIGN:We analyzed individualized records of 95,176 graduates who completed the 1997 to 2004 Associatio...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2006.04.026

    authors: Andriole DA,Klingensmith ME,Jeffe DB

    更新日期:2006-08-01 00:00:00

  • Pathologic response to induction chemotherapy in locally advanced carcinoma of the breast: a determinant of outcome.

    abstract:BACKGROUND:The prognosis for patients with locally advanced carcinoma of the breast remains poor. This study examines the pathologic evidence of response of the mammary tumor and axillary nodes after preoperative chemotherapy. We sought to determine if there was a relationship between the histologic response and clinic...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Sataloff DM,Mason BA,Prestipino AJ,Seinige UL,Lieber CP,Baloch Z

    更新日期:1995-03-01 00:00:00

  • Outpatient Laparoscopic Appendectomy: Is It Time to End the Discussion?

    abstract:BACKGROUND:Laparoscopic appendectomy is typically associated with inpatient hospitalization averaging between 1 and 2 days. In July 2010, a prospective protocol for outpatient laparoscopic appendectomy was adopted at our institution. Patients were dismissed from the post-anesthesia recovery room or day surgery if they ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.12.053

    authors: Frazee RC,Abernathy SW,Isbell CL,Isbell T,Regner JL,Smith RD

    更新日期:2016-04-01 00:00:00

  • Management of 1- to 2-cm Carcinoid Tumors of the Appendix: Using the National Cancer Data Base to Address Controversies in General Surgery.

    abstract:BACKGROUND:The management of 1- to 2-cm appendiceal carcinoid tumors remains controversial. Here we use the National Cancer Data Base (NCDB) to compare long-term outcomes for patients treated via resection of the primary tumor alone vs right hemicolectomy (RHC). STUDY DESIGN:The 1998 to 2011 NCDB User File was queried...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2015.01.005

    authors: Nussbaum DP,Speicher PJ,Gulack BC,Keenan JE,Ganapathi AM,Englum BR,Tyler DS,Blazer DG 3rd

    更新日期:2015-05-01 00:00:00

  • Portal vein resection in borderline resectable pancreatic cancer: a United Kingdom multicenter study.

    abstract:BACKGROUND:Until recently, in the United Kingdom, borderline resectable pancreatic cancer with invasion into the portomesenteric veins often resulted in surgical bypass because of the presumed high risk for complications and the uncertainty of a survival benefit associated with a vascular resection. Portomesenteric vei...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2013.11.017

    authors: Ravikumar R,Sabin C,Abu Hilal M,Bramhall S,White S,Wigmore S,Imber CJ,Fusai G,UK Vascular Resection in Pancreatic Cancer Study Group.

    更新日期:2014-03-01 00:00:00

  • Comparison of risk-adjusted 30-day postoperative mortality and morbidity in Department of Veterans Affairs hospitals and selected university medical centers: vascular surgical operations in men.

    abstract:BACKGROUND:In response to a Congressional mandate to compare risk-adjusted surgical outcomes from Department of Veterans Affairs (VA) hospitals with those from private-sector hospitals, the National Surgical Quality Improvement Program was initiated in the VA system and then was developed in a select group of universit...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2007.02.066

    authors: Hutter MM,Lancaster RT,Henderson WG,Khuri SF,Mosca C,Johnson RG,Abbott WM,Cambria RP

    更新日期:2007-06-01 00:00:00

  • Comparison of mortality risk adjustment using a clinical data algorithm (American College of Surgeons National Surgical Quality Improvement Program) and an administrative data algorithm (Solucient) at the case level within a single institution.

    abstract:BACKGROUND:There is great interest in efficiently evaluating health care quality, but there is controversy over the use of administrative versus clinical data methods. We sought to compare actual mortality with risk-adjusted expected mortality in a sample population calculated by two different methods; one based on pre...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2007.08.013

    authors: Hall BL,Hirbe M,Waterman B,Boslaugh S,Dunagan WC

    更新日期:2007-12-01 00:00:00

  • Improved long-term survival of dialysis patients after near-total parathyroidectomy.

    abstract:BACKGROUND:Severe secondary hyperparathyroidism, which is associated with life-threatening complications, can develop in dialysis-dependent end-stage renal disease patients. The aim of this study was to compare short- and long-term mortality in dialysis patients who underwent near-total parathyroidectomy (NTPTX) and ma...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.12.046

    authors: Sharma J,Raggi P,Kutner N,Bailey J,Zhang R,Huang Y,Herzog CA,Weber C

    更新日期:2012-04-01 00:00:00

  • Development and Validation of a Methodology to Reduce Mortality Using the Veterans Affairs Surgical Quality Improvement Program Risk Calculator.

    abstract:BACKGROUND:To identify patients with a high risk of 30-day mortality after elective surgery, who may benefit from referral for tertiary care, an institution-specific process using the Veterans Affairs Surgical Quality Improvement Program (VASQIP) Risk Calculator was developed. The goal was to develop and validate the m...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2016.12.033

    authors: Keller DS,Kroll D,Papaconstantinou HT,Ellis CN

    更新日期:2017-04-01 00:00:00

  • Learning Curve for Surgeons Adopting Transcarotid Artery Revascularization Based on the Vascular Quality Initiative-Transcarotid Artery Revascularization Surveillance Project.

    abstract:BACKGROUND:Transcarotid artery revascularization (TCAR) with flow reversal was recently introduced as a novel technique for carotid artery stenting (CAS). We examined the learning curve of surgeons adopting TCAR based on data from the Vascular Quality Initiative (VQI-TCAR Surveillance Project; TSP). STUDY DESIGN:We id...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2019.09.020

    authors: Kashyap VS,King AH,Liang P,Eldrup-Jorgensen J,Wang GJ,Malas MB,Nolan BW,Cronenwett JL,Schermerhorn ML

    更新日期:2020-01-01 00:00:00

  • Isolated liver metastases from neuroendocrine tumors: does resection prolong survival?

    abstract:BACKGROUND:Neuroendocrine tumors commonly metastasize to the liver. Although surgical resection is considered a treatment option for patients with localized metastases confined to the liver, the longterm survival benefit of liver resection has not been clearly demonstrated. We examined the survival of patients undergoi...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(98)00099-4

    authors: Chen H,Hardacre JM,Uzar A,Cameron JL,Choti MA

    更新日期:1998-07-01 00:00:00

  • Peripheral ports are a new option for central venous access.

    abstract:BACKGROUND:Peripheral ports represent a new option for central venous access that have a low complication rate while providing long duration. This study provides five years of evaluation of this device. STUDY DESIGN:All patients had follow-up evaluation concurrently, with detailed information collected for the first 7...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: Schuman E,Ragsdale J

    更新日期:1995-04-01 00:00:00

  • Surgical critical care and private practice surgeons: a different world out there!

    abstract:BACKGROUND:Few graduating residents seek surgical critical care (SCC) fellowships; fewer than half of positions fill. We hypothesized substantial differences exist in practice patterns and attitudes between SCC surgeons in academic practice (ACs) and in private practice (PVTs). STUDY DESIGN:A survey instrument was sen...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2007.10.004

    authors: Cohn SM,Price MA,Stewart RM,Corneille MG,Myers JG,McCarthy J,Jonas RB,Hargis SM,Dent DL

    更新日期:2008-03-01 00:00:00

  • A novel scoring system for predicting postoperative venous thromboembolic complications in patients after open aortic surgery.

    abstract:BACKGROUND:Although the overall incidence of venous thromboembolism (VTE) after open aortic surgery is low, it is not known whether specific factors can place patients at increased risk for this complication. The goal of our study was to identify patient and procedure characteristics that are associated with increased ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2011.12.031

    authors: Scarborough JE,Cox MW,Mureebe L,Pappas TN,Shortell CK

    更新日期:2012-04-01 00:00:00

  • Comparison of costs between laparoscopic and open Nissen fundoplication: a prospective randomized study with a 3-month followup.

    abstract:BACKGROUND:Laparoscopic antireflux surgery has replaced conventional operation despite the fact that currently no randomized trials have been published regarding its cost effectiveness. The objective of the present study was to compare costs and some short-term outcomes of laparoscopic and open Nissen fundoplication. ...

    journal_title:Journal of the American College of Surgeons

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s1072-7515(98)00328-7

    authors: Heikkinen TJ,Haukipuro K,Koivukangas P,Sorasto A,Autio R,Södervik H,Mäkelä H,Hulkko A

    更新日期:1999-04-01 00:00:00

  • Comprehensive Analysis of the Effect of Ketorolac Administration after Pancreaticoduodenectomy.

    abstract:BACKGROUND:Outcome improvement is a major goal of pancreatic surgery. Such efforts include decreasing perioperative narcotic use to optimize care and reduce potential contributions to the opioid crisis. Ketorolac, a frequent component of opioid-minimizing recovery pathways, has not been universally adopted over concern...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2020.02.024

    authors: Kunstman JW,Brandt WS,Azar SA,Jean RA,Salem RR

    更新日期:2020-06-01 00:00:00

  • Zero mortality after 152 consecutive pancreaticoduodenectomies with pancreaticogastrostomy.

    abstract:BACKGROUND:Since 1968, there have been three published reports in the United States literature of 41, 118, and 145 consecutive patients undergoing pancreaticoduodenectomy without mortality. In all of these series, the pancreatic remnant was anastomosed to the jejunum. STUDY DESIGN:This study was designed to review 152...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/S1072-7515(03)00331-4

    authors: Aranha GV,Hodul PJ,Creech S,Jacobs W

    更新日期:2003-08-01 00:00:00

  • Insurance coverage is associated with mortality after gunshot trauma.

    abstract:BACKGROUND:Poor access to adequate health care coverage is associated with poor outcomes for many chronic medical conditions. We hypothesized that insurance coverage is also associated with mortality after gunshot trauma. STUDY DESIGN:The trauma records for gunshot victims and their insurance status were reviewed at o...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2009.12.002

    authors: Dozier KC,Miranda MA Jr,Kwan RO,Cureton EL,Sadjadi J,Victorino GP

    更新日期:2010-03-01 00:00:00

  • The management of infectious and noninfectious anorectal complications in patients with leukemia.

    abstract:BACKGROUND:Infectious and noninfectious anorectal complications may occur in patients undergoing therapy for leukemia. Controversy surrounds the treatment of this problem in immunocompromised patients. STUDY DESIGN:A retrospective review of the medical records of 83 patients with acute or chronic leukemia in whom anor...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:

    authors: North JH Jr,Weber TK,Rodriguez-Bigas MA,Meropol NJ,Petrelli NJ

    更新日期:1996-10-01 00:00:00

  • Resident participation in index laparoscopic general surgical cases: impact of the learning environment on surgical outcomes.

    abstract:BACKGROUND:The NSQIP database enables measurement of postoperative outcomes across a spectrum of practice settings. This allows for observations about potential effects of resident participation in surgical care during training. STUDY DESIGN:We queried the NSQIP database for 6 index laparoscopic surgical procedures pe...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2012.08.014

    authors: Davis SS Jr,Husain FA,Lin E,Nandipati KC,Perez S,Sweeney JF

    更新日期:2013-01-01 00:00:00

  • Surgical management of patients with synchronous colorectal liver metastasis: a multicenter international analysis.

    abstract:BACKGROUND:The goal of this study was to investigate the surgical management and outcomes of patients with primary colorectal cancer (CRC) and synchronous liver metastasis (sCRLM). STUDY DESIGN:Using a multi-institutional database, we identified 1,004 patients treated for sCRLM between 1982 and 2011. Clinicopathologic...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamcollsurg.2012.12.029

    authors: Mayo SC,Pulitano C,Marques H,Lamelas J,Wolfgang CL,de Saussure W,Choti MA,Gindrat I,Aldrighetti L,Barrosso E,Mentha G,Pawlik TM

    更新日期:2013-04-01 00:00:00

  • Prospective randomized single-blinded in vitro and ex vivo evaluation of new and reprocessed laparoscopic trocars.

    abstract:BACKGROUND:Reprocessing of single-use medical instruments has been proposed as a mechanism for managing the rising costs of health care. We compared the performance of new and reprocessed laparoscopic trocars. STUDY DESIGN:New and reprocessed laparoscopic trocars were evaluated. Testing consisted of visual and microsc...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jamcollsurg.2010.08.003

    authors: Mues AC,Haramis G,Casazza C,Okhunov Z,Badani KK,Landman J

    更新日期:2010-12-01 00:00:00

  • A636P is associated with early-onset colon cancer in Ashkenazi Jews.

    abstract:BACKGROUND:Hereditary predisposition to colorectal cancer most often manifests itself as familial adenomatous polyposis from mutations of APC, or hereditary nonpolyposis colorectal cancer, resulting from mutations of MSH2, MLH1, MSH6, or other genes. Previously, we described a rare founder mutation MSH2*1906C > G in As...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/S1072-7515(02)01808-2

    authors: Guillem JG,Rapaport BS,Kirchhoff T,Kolachana P,Nafa K,Glogowski E,Finch R,Huang H,Foulkes WD,Markowitz A,Ellis NA,Offit K

    更新日期:2003-02-01 00:00:00

  • Surgical treatment of early-stage breast cancer in the Department of Defense Healthcare System.

    abstract:BACKGROUND:The choice between breast-conserving surgery and modified radical mastectomy in the treatment of women with early stage breast cancer in the Department of Defense Healthcare System may be influenced by demographic factors. STUDY DESIGN:The Department of Defense Automated Central Tumor Registry (ACTUR) was q...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(00)00803-6

    authors: Kelemen JJ 3rd,Poulton T,Swartz MT,Jatoi I

    更新日期:2001-03-01 00:00:00

  • Benefits of Multimodal Enhanced Recovery Pathway in Patients Undergoing Open Ventral Hernia Repair.

    abstract:BACKGROUND:Use of Enhanced Recovery After Surgery (ERAS) pathways have evidenced improved outcomes in several surgical specialties. The effectiveness of ERAS pathways specific to hernia surgery, however, has not yet been investigated. We hypothesized that our ERAS pathway would accelerate functional recovery and shorte...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/j.jamcollsurg.2016.02.015

    authors: Majumder A,Fayezizadeh M,Neupane R,Elliott HL,Novitsky YW

    更新日期:2016-06-01 00:00:00

  • Anorectal Function and Quality of Life after Transrectal Rigid-Hybrid Natural Orifice Translumenal Endoscopic Sigmoidectomy.

    abstract:BACKGROUND:In transrectal rigid-hybrid natural orifice translumenal endoscopic sigmoidectomy (trNS), extraction-site laparotomy is avoided, which reduces postoperative pain and improves recovery time. However, current research evaluating anorectal function after trNS is limited. This study aims to evaluate clinical con...

    journal_title:Journal of the American College of Surgeons

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jamcollsurg.2016.04.002

    authors: Steinemann DC,Zerz A,Germann S,Lamm SH

    更新日期:2016-08-01 00:00:00

  • Cardiorenal effects of adenosine subtype 1 (A1) receptor inhibition in an experimental model of heart failure.

    abstract:BACKGROUND:Elaboration of a number of bioactive substances, including adenosine, occurs in heart failure (HF). Adenosine, through the adenosine subtype 1 (A1) receptor, can reduce renal perfusion pressure and glomerular filtration rate and increase tubular sodium reabsorption, which can affect natriuresis and aquaresis...

    journal_title:Journal of the American College of Surgeons

    pub_type: 杂志文章

    doi:10.1016/s1072-7515(02)01136-5

    authors: Lucas DG Jr,Hendrick JW,Sample JA,Mukherjee R,Escobar GP,Smits GJ,Crawford FA Jr,Spinale FG

    更新日期:2002-05-01 00:00:00