False-positive In-111 DTPA octreotide scintigraphy in bilateral tibial insufficiency fracture.

Abstract:

:We present a case of bilateral tibial insufficiency fracture in which indium (In)-111 diethylenetriamine pentaacetic acid (DTPA) octreotide scan showed increased activity in the region of the fracture. The scan was performed in a 5-year-old girl with severe refractory hypertension and elevated plasma metanephrines for evaluation of possible neuroendocrine tumor. Octreotide scan is usually positive in neuroendocrine and some other tumors but also shows positive results in a number of other conditions. However insufficiency fracture has not been reported as a positive finding on octreotide scan in children. This may relate to the expression of somatostatin membrane receptor in activated white blood cells or expression of somatostatin receptors by bone cells.

journal_name

Pediatr Radiol

journal_title

Pediatric radiology

authors

Vali R,Ranson M,Harvey E,Shammas A

doi

10.1007/s00247-014-3029-6

subject

Has Abstract

pub_date

2015-01-01 00:00:00

pages

129-32

issue

1

eissn

0301-0449

issn

1432-1998

journal_volume

45

pub_type

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