Abstract:
:Chronic measles virus infection of the brain causes subacute sclerosing panencephalitis (SSPE), a progressive, relentless fatal disorder. We report a 52-year-old male who developed focal, chronic persistent measles virus infection of the brain following interferon and ribavirin therapy for hepatitis C, and who responded to steroid therapy. This case, diametrically different from SSPE, has 2 unique features, its focal nature and its permissive response to steroids, that may add to the understanding of the pathogenesis of SSPE and the mechanism enabling viruses to evade the immune response and establish persistent brain infection.
journal_name
Ann Neuroljournal_title
Annals of neurologyauthors
Steiner I,Livneh V,Hoffmann C,Nass D,Mor O,Chapman Jdoi
10.1002/ana.24183subject
Has Abstractpub_date
2014-06-01 00:00:00pages
967-70issue
6eissn
0364-5134issn
1531-8249journal_volume
75pub_type
杂志文章abstract::A 51-year-old man presented with a six-year history of gradually progressive exertional dyspnea. His complaint was attributed to increasing age, but evaluation finally led to a diagnosis of diaphragmatic paralysis. Neurological examination disclosed only minimal evidence of weakness of limb muscles. Electromyographic ...
journal_title:Annals of neurology
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doi:10.1002/ana.410090618
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abstract::In patients with the frontal variant of frontotemporal lobar degeneration (fv-FTLD), behavioral abnormalities may vary from apathy with motor slowness (apathetic form) to disinhibition with agitation (disinhibited form). These clinical presentations may be related to specific regional cerebral dysfunction and to defic...
journal_title:Annals of neurology
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abstract::Axonal loss is thought to be a likely cause of persistent disability after a multiple sclerosis relapse; therefore, noninvasive in vivo markers specific for axonal loss are needed. We used optic neuritis as a model of multiple sclerosis relapse to quantify axonal loss of the retinal nerve fiber layer (RNFL) and second...
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410440208
更新日期:1998-08-01 00:00:00
abstract:OBJECTIVE:Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the human central nervous system. Although the clinical impact of gray matter pathology in MS brains is unknown, 30 to 40% of MS patients demonstrate memory impairment. The molecular basis of this memory dysfunction has not yet been investiga...
journal_title:Annals of neurology
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更新日期:2011-03-01 00:00:00
abstract::Dopa-responsive dystonia (DRD) is one form of childhood-onset idiopathic torsion dystonia. Adult-onset parkinsonism has appeared in several previously unaffected members in families with DRD suggesting that this may be an additional phenotypical expression of the disease. We report a family with DRD in which 2 women a...
journal_title:Annals of neurology
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doi:10.1002/ana.410320502
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journal_title:Annals of neurology
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更新日期:2013-09-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章,评审
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更新日期:1990-05-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.21225
更新日期:2008-02-01 00:00:00
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abstract::Three-dimensional (volume) magnetic resonance angiography is a noninvasive technique that images the intracranial and cervical arterial vasculature without contrast agents. Twenty-four children with strokes had combined parenchymal magnetic resonance imaging and magnetic resonance angiography 1 day to 4 years after ac...
journal_title:Annals of neurology
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doi:10.1002/ana.410290603
更新日期:1991-06-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.410350410
更新日期:1994-04-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410110614
更新日期:1982-06-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410030207
更新日期:1978-02-01 00:00:00
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更新日期:2019-03-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410230716
更新日期:1988-01-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.21660
更新日期:2009-06-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410340507
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:To design a new class of selective neuronal nitric oxide synthase (NOS) inhibitors, and demonstrate that administration in a rabbit model for cerebral palsy (CP) prevents hypoxia-ischemia-induced deaths and reduces the number of newborn kits exhibiting signs of CP. METHODS:We used a novel computer-based drug...
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doi:10.1002/ana.21555
更新日期:2009-02-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:
更新日期:2001-03-01 00:00:00
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journal_title:Annals of neurology
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doi:10.1002/ana.410230402
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abstract::To this day, the cause of multiple system atrophy (MSA) remains stubbornly enigmatic. A growing body of observations regarding the clinical, morphological, and biochemical phenotypes of MSA has been published, but the interested student is still left without a clue as to its underlying cause. MSA has long been conside...
journal_title:Annals of neurology
pub_type: 杂志文章,评审
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更新日期:2008-09-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章,评审
doi:10.1002/ana.10628
更新日期:2003-01-01 00:00:00
abstract::Benzodiazepines can regulate neoplastic growth and immune response through specific peripheral benzodiazepine receptors. We investigated the presence of peripheral and classic central benzodiazepine receptors as well as diazepam-binding inhibitor, an endogenous ligand of both types of receptors, in different human cer...
journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410260411
更新日期:1989-10-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.410150722
更新日期:1984-01-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.10066
更新日期:2001-12-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章,评审
doi:10.1002/ana.410320213
更新日期:1992-08-01 00:00:00
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journal_title:Annals of neurology
pub_type: 杂志文章
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更新日期:1978-08-01 00:00:00
abstract:OBJECTIVE:Chronic seizures in women can have adverse effects on reproductive function, such as polycystic ovarian syndrome, but it has been difficult to dissociate the effects of epilepsy from the role of antiepileptic drugs. To distinguish the effects of chronic seizures from medication, we used the laboratory rat, be...
journal_title:Annals of neurology
pub_type: 杂志文章
doi:10.1002/ana.21518
更新日期:2008-12-01 00:00:00