Abstract:
:Pituitary cysts are fairly often found incidentally in anatomical studies, but symptomatic cysts are relatively uncommon. In this study, the histological characteristics of 42 asymptomatic and three symptomatic Rathke's cleft cysts were examined and compared. The 42 cysts found incidentally at autopsy were classified as small (less than 1 mm in diameter), medium (1 to 5 mm), or large (over 5 mm). There were 23 small (55%), 13 medium (31%), and six large (14%) cysts. The mean ages of the three patient groups were 66, 60, and 53 years, respectively. Flattened epithelial cells were the most common cells in small cysts, while cuboidal to columnar epithelial cells were more prevalent in medium and large cysts. The larger cysts tended to contain cilia. The three symptomatic cysts were histologically confirmed to be Rathke's cleft cysts by their characteristic ciliated columnar epithelial lining. No essential histological differences were observed between asymptomatic and symptomatic cysts, and the mechanism of change from asymptomatic to symptomatic Rathke's cleft cyst was not clarified. Small nests of epithelium at the junction of the pars tuberalis and pituitary stalk are considered to be remnants of Rathke's pouch and are thought to give rise to craniopharyngioma. In their most typical forms, Rathke's cleft cysts and craniopharyngiomas are histologically distinguishable, craniopharyngiomas being composed of stratified squamous epithelium and simple Rathke's cleft cysts of a layer of cuboidal or columnar epithelium on a basement membrane.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Neurol Med Chir (Tokyo)journal_title
Neurologia medico-chirurgicaauthors
Keyaki A,Hirano A,Llena JFdoi
10.2176/nmc.29.88subject
Has Abstractpub_date
1989-02-01 00:00:00pages
88-93issue
2eissn
0470-8105issn
1349-8029pii
JST.Journalarchive/nmc1959/29.88journal_volume
29pub_type
杂志文章abstract::A 38-year-old female presented with vertigo, right hearing disturbance, and slight headache which were treated medically. However, she suddenly developed severe headache with vomiting and vertigo. Computed tomography revealed subarachnoid hemorrhage, and right vertebral angiography disclosed a rare aneurysm at the dis...
journal_title:Neurologia medico-chirurgica
pub_type: 杂志文章
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
pub_type: 杂志文章
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
pub_type: 杂志文章
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
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journal_title:Neurologia medico-chirurgica
pub_type: 杂志文章,评审
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