Malignant fibrous histiocytoma in the parietal bone.

Abstract:

:Malignant fibrous histiocytomas (MFHs) are mesenchymal tumors, usually arising in soft tissue of the extremities and are remarkably resistant to radiation and chemotherapy. A 45-year-old female presented with a rare case of MFH originating in the cranial bone manifesting as a lump in the left parietal region with no neurological abnormality. Neuroimaging revealed the presence of an osteolytic tumor in the left parietal bone invading into muscle and subdural region, penetrating through the dura. Selective external carotid angiography disclosed a marked tumor stain. Examination of the whole body excluded neoplastic disease elsewhere. The patient was treated by surgical excision, radiation, and two courses of multi-drug chemotherapy using cyclophosphamide, doxorubicin, vincristine, and prednisolone. Since there is no established treatment against this malignancy, a longer follow-up is necessary to determine whether cure has been achieved.

authors

Yoshida D,Harashima K,Node Y,Kojima T,Shimura T,Teramoto A

doi

10.2176/nmc.38.359

subject

Has Abstract

pub_date

1998-06-01 00:00:00

pages

359-62

issue

6

eissn

0470-8105

issn

1349-8029

pii

JST.Journalarchive/nmc1959/38.359

journal_volume

38

pub_type

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