Clinical, demographic, and pharmacologic features of nursing home residents with Huntington's disease.

Abstract:

BACKGROUND:The purpose of this descriptive, retrospective analysis was to develop a demographic and clinical profile of nursing home residents with a diagnosis of Huntington's disease (HD). METHODS:Queries were made of a large data repository of linked and de-identified Minimum Data Set version 3.0 and prescription claims records, for the time period of October 1, 2010 through March 31, 2012. RESULTS:Of 249,811 residents, 340 (0.14%) had a diagnosis of HD; 61% were female and 77.9% were Caucasian. The age range mode was 55-59 years (15%). Approximately one-half of the residents with HD exhibited communication difficulties, 78% had moderate or severe cognitive impairment, and most have significant functional limitations. Depression, dementia, anxiety, psychosis, and bipolar disease were present in 59.4%, 50.9%, 35.9%, and 23.2%, and 9.7%, respectively. Only 21% of residents with HD exhibited troublesome behavioral symptoms. Comorbidities of diabetes and cancer were uncommon (0.3%). Use of physical restraints (excluding bed rails) was considerably higher in residents with HD than in the general nursing home population. Falls were documented in almost one-half of residents. Antipsychotics were used in 61.6% of residents; 16.2% had psychotic symptoms. One was treated with tetrabenazine. Anxiolytics were received by 59.1% of residents, whereas only 35.9% had anxiety noted on Minimum Data Set records. CONCLUSIONS:The prevalence of HD in US nursing homes is very low (0.14%). Affected residents have significant cognitive and functional impairments, but problematic behaviors are present in only a minority. Serious comorbidities such as cancer and diabetes are rare. Antipsychotics, antidepressants, and anxiolytics are the mainstays of treatment.

journal_name

J Am Med Dir Assoc

authors

Zarowitz BJ,O'Shea T,Nance M

doi

10.1016/j.jamda.2014.01.010

subject

Has Abstract

pub_date

2014-06-01 00:00:00

pages

423-8

issue

6

eissn

1525-8610

issn

1538-9375

pii

S1525-8610(14)00072-3

journal_volume

15

pub_type

杂志文章
  • Introducing a new incontinence management system for nursing home residents.

    abstract:OBJECTIVES:To describe current practices of incontinence care in nursing homes (NHs) provided by certified nurse assistants (CNAs), and to evaluate the feasibility and acceptability of an integrated incontinence care product, the One Step Incontinence System (OSIS) in the NH setting. While the ultimate purpose of OSIS ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jamda.2006.10.001

    authors: Al-Samarrai NR,Uman GC,Al-Samarrai T,Alessi CA

    更新日期:2007-05-01 00:00:00

  • Nursing homes and end-of-life care in Japan.

    abstract:OBJECTIVES:To describe end-of-life care in Japanese nursing homes by comparing facility and characteristics of residents dying in nursing homes with those who had been transferred and had died in hospitals, and by comparing the quality of end-of-life care with hospitals and with their respective counterparts in the Uni...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2013.02.008

    authors: Ikegami N,Ikezaki S

    更新日期:2013-10-01 00:00:00

  • Prediction of 6-month mortality in nursing home residents with advanced dementia: validity of a risk score.

    abstract:OBJECTIVE:Prognostic information is important for guiding palliative care planning for patients with dementia. We aim to validate a risk score that uses Minimum Data Set (MDS) to estimate 6-month mortality for nursing home residents with advanced dementia. DESIGN:Two cohort studies. SETTING:Six nursing homes in The N...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamda.2007.05.004

    authors: van der Steen JT,Mitchell SL,Frijters DH,Kruse RL,Ribbe MW

    更新日期:2007-09-01 00:00:00

  • Risk factors for aspiration pneumonia in frail older people: a systematic literature review.

    abstract:OBJECTIVE:To systematically review the risks for aspiration pneumonia in frail older people and the contribution of bad oral health among the risk factors. DESIGN:Systematic literature review. SETTING:PubMed (Medline), Web of Science, Cochrane Library, EMBASE, and CINAHL were searched for eligible studies, published ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2010.12.099

    authors: van der Maarel-Wierink CD,Vanobbergen JN,Bronkhorst EM,Schols JM,de Baat C

    更新日期:2011-06-01 00:00:00

  • The preliminary impact of Maryland's medical director and attending physician regulations.

    abstract:OBJECTIVES:To identify the impact of the regulations implemented in Maryland in 2001, related to nursing home attending physicians and medical directors, and nursing home quality assurance requirements, on Maryland nursing homes, administrators, and physicians. DESIGN:Two surveys were mailed to all nursing home admini...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1097/01.JAM.0000066022.74526.CF

    authors: Boyce BF,Bob H,Levenson SA

    更新日期:2003-05-01 00:00:00

  • Predicting Adverse Health Outcomes in Nursing Homes: A 9-Year Longitudinal Study and Development of the FRAIL-Minimum Data Set (MDS) Quick Screening Tool.

    abstract:OBJECTIVES:To examine the predictive validity of a quick frailty screening tool, the FRAIL-NH, for adverse health outcomes in nursing home residents, using variables from the Minimum Data Set (MDS). The screening items were compiled from the MDS for potential direct application in long-term care facilities using this h...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.09.006

    authors: Luo H,Lum TY,Wong GH,Kwan JS,Tang JY,Chi I

    更新日期:2015-12-01 00:00:00

  • What factors contribute to successful appeals of nursing homes' deficiencies in the informal dispute resolution process?

    abstract:OBJECTIVES:To determine what factors contribute to successful appeals of nursing home deficiencies in the Informal Dispute Resolution (IDR) process. DESIGN:We merged Centers for Medicare and Medicaid Services' data about IDRs with Online Survey, Certification, and Reporting data about nursing home characteristics. We ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2012.09.015

    authors: Mukamel DB,Li Y,Weimer DL,Spector WD,Bailey L,Harrington C

    更新日期:2013-02-01 00:00:00

  • Developing Evidence for Football (Soccer) Reminiscence Interventions Within Long-term Care: A Co-operative Approach Applied in Scotland and Spain.

    abstract::Loneliness is a common experience within long-term care and, to promote well-being and quality of life among people with dementia, it is important to draw upon a repertoire of strategies that provide social stimulation, companionship, and enjoyment. This paper describes and reflects on a program of co-operative social...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2017.01.013

    authors: Coll-Planas L,Watchman K,Doménech S,McGillivray D,O'Donnell H,Tolson D

    更新日期:2017-04-01 00:00:00

  • Outcomes of Nursing Home COVID-19 Patients by Initial Symptoms and Comorbidity: Results of Universal Testing of 1970 Residents.

    abstract:OBJECTIVE:Clinical implications of asymptomatic cases of the novel coronavirus disease 2019 (COVID-19) in nursing homes remain poorly understood. We assessed the association of symptom status and medical comorbidities on mortality and hospitalization risk associated with COVID-19 in residents across 15 nursing homes in...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.10.011

    authors: Tang O,Bigelow BF,Sheikh F,Peters M,Zenilman JM,Bennett R,Katz MJ

    更新日期:2020-12-01 00:00:00

  • Spontaneous Reversion of Mild Cognitive Impairment to Normal Cognition: A Systematic Review of Literature and Meta-Analysis.

    abstract:OBJECTIVES:The issue of subjects with mild cognitive impairment (MCI) reverting to normal cognition (NC) has to date been taken in limited consideration, and no conclusive data are available on the rate of reversion. We aimed at systematically reviewing available longitudinal studies on MCI and meta-analyzing data with...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.jamda.2016.06.020

    authors: Canevelli M,Grande G,Lacorte E,Quarchioni E,Cesari M,Mariani C,Bruno G,Vanacore N

    更新日期:2016-10-01 00:00:00

  • Low skeletal muscle mass and risk of functional decline in elderly community-dwelling women: the prospective EPIDOS study.

    abstract:OBJECTIVES:To assess relationships between low skeletal muscle mass (SMM) and functional decline in community-dwelling elderly women. DESIGN:Secondary analysis of data from EPIDOS, a French prospective observational multicenter cohort study of osteoporosis epidemiology. SETTING:One center in France between 1992 and 1...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jamda.2012.12.002

    authors: Amigues I,Schott AM,Amine M,Gelas-Dore B,Veerabudun K,Paillaud E,Beauchet O,Rolland Y,Canouï Poitrine F,Bonnefoy M

    更新日期:2013-05-01 00:00:00

  • The Geriatric Patient: The Ideal One for Chest Ultrasonography? A Review From the Chest Ultrasound in the Elderly Study Group (GRETA) of the Italian Society of Gerontology and Geriatrics (SIGG).

    abstract:OBJECTIVES:To investigate the current evidence on the use of point-of-care chest ultrasonography in older patients and geriatric settings and present the current state of the art of chest ultrasound applications. DESIGN:Special article based on a literature review with narrative analyses and expert clinical knowledge....

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2019.06.018

    authors: Ticinesi A,Scarlata S,Nouvenne A,Lauretani F,Incalzi RA,Ungar A,GRETA (Gruppo di Ricerca sull’Ecografia Toracica nell’Anziano) Group of the Italian Society of Gerontology and Geriatrics (SIGG).

    更新日期:2020-04-01 00:00:00

  • Optimizing Eating Performance for Long-Term Care Residents With Dementia: Testing the Impact of Function-Focused Care for Cognitively Impaired.

    abstract:OBJECTIVES:The objective of this study was to evaluate the impact of a well-developed theory-based function-focused care for cognitively impaired (FFC-CI) intervention on eating performance among long-term care (LTC) residents with moderate-to-severe cognitive impairment. DESIGN:A secondary analysis of longitudinal da...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.06.023

    authors: Liu W,Galik E,Nahm ES,Boltz M,Resnick B

    更新日期:2015-12-01 00:00:00

  • Factors Associated With Hospital Presentation of Self-Harm Among Older Canadians in Long-Term Care: A 12-Year Cohort Study.

    abstract:OBJECTIVES:This study aimed to examine the incidence of, and factors associated with, hospital presentation for self-harm among older Canadians in long-term care (LTC). DESIGN:Retrospective cohort study. SETTING AND PARTICIPANTS:The LTC data were collected using Resident Assessment Instrument-Minimum Data Set (RAI-MD...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.12.022

    authors: Chai Y,Luo H,Yip PSF,Perlman CM,Hirdes JP

    更新日期:2021-01-15 00:00:00

  • A systematic review of malnutrition screening tools for the nursing home setting.

    abstract:RATIONALE:Malnutrition screening among nursing home residents is often performed with tools developed for use among older subjects, and sometimes with tools designed for an adult population. Only a few tools have been designed specifically for the nursing home setting. This systematic review assesses the criterion and ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2013.10.006

    authors: van Bokhorst-de van der Schueren MAE,Guaitoli PR,Jansma EP,de Vet HCW

    更新日期:2014-03-01 00:00:00

  • Discharge coordinator intervention prevents hospitalizations in patients with COPD: a randomized controlled trial.

    abstract:OBJECTIVES:To test whether coordination of discharge from hospital reduces hospitalizations in patients with chronic obstructive pulmonary disease (COPD). DESIGN:Randomized controlled clinical trial. SETTING:Specialized pulmonary hospital. PARTICIPANTS:Patients hospitalized for an acute exacerbation of COPD. INTERV...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jamda.2013.03.003

    authors: Lainscak M,Kadivec S,Kosnik M,Benedik B,Bratkovic M,Jakhel T,Marcun R,Miklosa P,Stalc B,Farkas J

    更新日期:2013-06-01 00:00:00

  • Association Between Malnutrition and Oral Health in Dutch Nursing Home Residents: Results of the LPZ Study.

    abstract:INTRODUCTION:According to the World Health Organization (WHO) and FDI World Dental Federation (FDI), malnutrition and bad oral health are of great concern to global health, especially among the older population. This study aimed to assess the associations between oral health problems ([artificial] teeth problems, chewi...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2017.05.022

    authors: Huppertz VAL,van der Putten GJ,Halfens RJG,Schols JMGA,de Groot LCPGM

    更新日期:2017-11-01 00:00:00

  • Predicting Short-Term Risk of Falls in a High-Risk Group With Dementia.

    abstract:OBJECTIVES:To develop a prognostic model to predict the probability of a short-term fall (within the next 7 to 30 days) in older adults with dementia. DESIGN:Prospective observational study. SETTING AND PARTICIPANTS:Fifty-one individuals with dementia at high risk of falls from a specialized dementia inpatient unit. ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.07.030

    authors: Mehdizadeh S,Sabo A,Ng KD,Mansfield A,Flint AJ,Taati B,Iaboni A

    更新日期:2020-09-05 00:00:00

  • Geriatric dermatology review: Major changes in skin function in older patients and their contribution to common clinical challenges.

    abstract::There is a paucity of data to guide evidence-based treatment decisions in managing older dermatologic patients, in part because of the frequent exclusion of older adults from clinical trials. Hence, we provide a comprehensive review of important conditions in geriatric dermatology, or "dermatogeriatrics." It is our ho...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2013.02.014

    authors: Chang AL,Wong JW,Endo JO,Norman RA

    更新日期:2013-10-01 00:00:00

  • Associations among processes and outcomes of care for Medicare nursing home residents with acute heart failure.

    abstract:OBJECTIVE:To characterize Medicare skilled nursing facility (SNF) residents who become acutely ill with heart failure (HF) and assess the association between the outcomes of rehospitalization and mortality, and severity of the acute exacerbation, comorbidity, and processes of care. DESIGN:SNF medical record review of ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1097/01.JAM.0000073964.19754.C0

    authors: Hutt E,Frederickson E,Ecord M,Kramer AM

    更新日期:2003-07-01 00:00:00

  • Health Information Technologies: Which Nursing Homes Adopted Them?

    abstract:PURPOSE:Long-term care facilities have lagged heavily behind other health providers in adopting health information technology (IT). This article examines the facility characteristics that are associated with health IT adoption. DESIGN AND METHODS:This study is a secondary data analysis of information gathered between ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2016.02.028

    authors: Zhang N,Lu SF,Xu B,Wu B,Rodriguez-Monguio R,Gurwitz J

    更新日期:2016-05-01 00:00:00

  • Methods of pain assessment in residents of long-term care facilities: a pilot study.

    abstract:OBJECTIVES:Structured programs for routine pain assessment and treatment are necessary to optimize care for residents of long-term care facilities (LTCFs). A pilot study was designed to develop, implement, and evaluate a system for pain assessment and monitoring in a LTCF. Additional goals were to determine whether a v...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 临床试验,杂志文章

    doi:10.1016/j.jamda.2004.12.024

    authors: Alexander BJ,Plank P,Carlson MB,Hanson P,Picken K,Schwebke K

    更新日期:2005-03-01 00:00:00

  • London Transfer Project: Reducing Medication Incidents After Discharge From Hospital to Long-term Care.

    abstract:BACKGROUND:Long-term care (LTC) homes expressed concern that patients had experienced medication incidents after hospital discharge as a result of poor coordination of care. OBJECTIVE:The London Transfer Project aimed to reduce LTC medication incidents by 50% within 48 hours of discharge from general medicine units at...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2018.09.037

    authors: Carson J,Gottheil S,Lawson S,Rice T

    更新日期:2019-04-01 00:00:00

  • Conceptualizing a Dynamic Fall Risk Model Including Intrinsic Risks and Exposures.

    abstract::Falls are a major cause of injury and disability in older people, leading to serious health and social consequences including fractures, poor quality of life, loss of independence, and institutionalization. To design and provide adequate prevention measures, accurate understanding and identification of person's indivi...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2017.08.001

    authors: Klenk J,Becker C,Palumbo P,Schwickert L,Rapp K,Helbostad JL,Todd C,Lord SR,Kerse N

    更新日期:2017-11-01 00:00:00

  • The influence of organizational context on best practice use by care aides in residential long-term care settings.

    abstract:OBJECTIVE:This study assessed individual and organizational context (work environment) factors that influence use of best practices by care aides (nursing assistants) in nursing homes. Little scientific attention has been focused on understanding best practice use in nursing homes and almost none on care aides. SETTIN...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2015.03.009

    authors: Estabrooks CA,Squires JE,Hayduk L,Morgan D,Cummings GG,Ginsburg L,Stewart N,McGilton K,Kang SH,Norton PG

    更新日期:2015-06-01 00:00:00

  • The role of nutrition and diet in Alzheimer disease: a systematic review.

    abstract::The role of nutrition in modulating Alzheimer disease (AD) remains uncertain. Persons ingesting a Mediterranean-type diet appear to be less likely to develop AD. Epidemiologically, food combinations rich in antioxidant vitamins reduced the risk of AD. Combination formulas (eg, Souvenaid) appear to have small effects o...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2013.01.014

    authors: Shah R

    更新日期:2013-06-01 00:00:00

  • Elderly residents at risk for being victims or offenders.

    abstract::The phenomenon of elderly sexual offenders is poorly catalogued, and is especially complex. In institutions, elderly people are often unrecognized victims of sexual abuse but are also at great risk for doing abuse toward vulnerable victims like children. The lack of attention to an elder's basic needs can endanger or ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2012.05.012

    authors: Corbi G,Grattagliano I,Catanesi R,Ferrara N,Yorston G,Campobasso CP

    更新日期:2012-09-01 00:00:00

  • Describing Differences Among Recent Immigrants and Long-Standing Residents Waiting for Long-Term Care: A Population-Based Retrospective Cohort Study.

    abstract:OBJECTIVES:Immigrants often face many unique cultural and logistical challenges in their health care that differ from nonimmigrants. We sought to describe and compare characteristics and the time to placement between recent immigrants and long-standing residents waiting for long-term care (LTC). DESIGN:Population-base...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.07.018

    authors: Qureshi D,Schumacher C,Talarico R,Lapenskie J,Tanuseputro P,Scott M,Hsu A

    更新日期:2020-08-25 00:00:00

  • To What Extent Do Local Nursing Home Prescribing Patterns Relate to Psychotropic Prescribing in Assisted Living?

    abstract:OBJECTIVE:In nursing homes (NHs), psychoactive medication use has received notable attention, but less is known about prescribing in assisted living (AL). This study examined how antipsychotic and antianxiety medication prescribing in AL compares with NHs. DESIGN:Observational, cross-sectional AL data linked to public...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章

    doi:10.1016/j.jamda.2020.11.037

    authors: Thomas K,Wretman CJ,Sloane PD,Carder P,Schwartz L,Beeber AS,Zimmerman S

    更新日期:2020-12-28 00:00:00

  • Health care decision-making capacity: a legal perspective for long-term care providers.

    abstract::While federal law establishes guidelines that designated facilities must follow in providing information about a patient's rights regarding self-determination in the health care decision-making process, state law determines the decision-making process and the legal requirements pertaining thereto. A person's capacity ...

    journal_title:Journal of the American Medical Directors Association

    pub_type: 杂志文章,评审

    doi:10.1016/j.jamda.2006.01.001

    authors: Zimring SD

    更新日期:2006-06-01 00:00:00