Abstract：
:Lead (Pb) that belongs to heavy metals is one of the major pollution components of the environment. Occupational and environmental exposure to lead can cause its absorption by the body and consequently exert toxic effects in the liver. In this paper biochemical determinants of hepatotoxicity caused by lead are presented. Generation of reactive oxygen species, disturbances in the cellular antioxidant system, lipid peroxidation, inhibition of enzymatic proteins and intercellular signaling are also discussed.
journal_name
Med Prjournal_title
Medycyna pracyauthors
Labudda Mdoi
10.13075/mp.5893.2013.0040subject
Has Abstractpub_date
2013-01-01 00:00:00pages
565-8issue
4eissn
0465-5893issn
2353-1339journal_volume
64pub_type
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