Abstract:
:Angiogenic therapies for critical limb ischemia were tested in a mouse model. The mice were anesthetized and their femoral arteries were ligated. The animals were treated with bone marrow mononuclear cells (BMMCs) alone, BMMCs combined with plasmid vector encoding granulocyte macrophage colony-stimulating factor (GM-CSF), received no treatment, or no intervention (controls). The degree of ischemia was monitored for 4 weeks using a visual scale. Muscle atrophy and strength were assessed at 4 weeks postoperatively; the mice were then killed. In treated animals, total necrosis of the limb was not found, the weight of the gastrocnemius and quadriceps muscles was significantly higher, functional ability and tissue regeneration were significantly increased, and muscle impairment and adipocyte presence were significantly reduced compared with untreated animals. At inducing angiogenesis, the BMMCs alone was more effective than BMMCs combined with plasmid vector encoding GM-CSF. Treated animals showed increased angiogenesis compared with ischemic untreated ones.
journal_name
Vasc Endovascular Surgjournal_title
Vascular and endovascular surgeryauthors
Reis PE,de Carvalho LP,Yasumura E,da Silva FH,Garcia BC,Beutel A,Sacramento CB,Baptista-Silva JC,de Campos RR,Takiya CM,Borojevic R,Han SWdoi
10.1177/1538574413518119subject
Has Abstractpub_date
2014-04-01 00:00:00pages
207-16issue
3eissn
1538-5744issn
1938-9116pii
1538574413518119journal_volume
48pub_type
杂志文章abstract::Leiomyosarcoma of the vascular origin is a rare malignant tumor. It originates from the smooth muscle cells of the media with intra- or extraluminal growth, and in most cases it arises in the inferior vena cava. The diagnosis is often delayed because the clinical symptoms of this disease are often nonspecific. Accurat...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574416637445
更新日期:2016-04-01 00:00:00
abstract::Nail-patella syndrome (NPS) is a rare disorder characterized by abnormal development of ectodermal and mesodermal tissues. Classically, NPS presents as a triad of nail dysplasia, dysplastic patellae, and bony exostoses of the ilia known as "iliac horns." Apart from dermatological and skeletal abnormalities, patients m...
journal_title:Vascular and endovascular surgery
pub_type:
doi:10.1177/1538574419888345
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:Our goal was to assess the outcomes of females compared to males treated with endovascular lower extremity interventions in order to determine optimal therapy based on gender. METHODS:We performed a retrospective review evaluating the outcomes of primary transluminal angioplasty (PTA) and PTA + stenting (PTA...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574411418008
更新日期:2011-11-01 00:00:00
abstract::Takayasu arteritis is a rare, chronic vasculitis of unknown etiology characterized by inflammation of the aorta and its main branches. Although Takayasu arteritis mostly affects women of childbearing age, there is a paucity in the literature on pregnancy associated with Takayasu arteritis. Pregnant patients are at inc...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574417698904
更新日期:2017-05-01 00:00:00
abstract::Spontaneous visceral artery dissections are a rare occurrence. Here we report a case of spontaneous celiac artery dissection that was treated without surgery. ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574407305462
更新日期:2008-02-01 00:00:00
abstract::We report a case of an abdominal aortic aneurysm (AAA) that underwent inflammatory transformation which we treated medically with corticosteroids. Medical therapy resulted in resolution of presenting symptoms and observed inflammatory changes. We review the clinical features, associated pathology, diagnostic, and ther...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574413510616
更新日期:2014-01-01 00:00:00
abstract::Although renal arteriovenous fistula (AVF) is an uncommon condition, it may lead to high cardiac output heart failure and renal insufficiency. Recently, percutaneous transcatheter embolization has replaced traditional surgery as the first line of treatment. We report a case of a 68-year-old male who presented with a r...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574414561230
更新日期:2014-10-01 00:00:00
abstract::Open surgical repair is the standard treatment for a ruptured infrarenal abdominal aortic aneurysm (rAAA). This approach is associated with mortality rates of up to 70%, with significant surgery-related morbidity among survivors. In selected patients, endoluminal repair (ER) of an rAAA under local anesthesia may allow...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440403800302
更新日期:2004-05-01 00:00:00
abstract::Internal iliac artery aneurysms are a rare variant of aorto-iliac aneurysm disease. They are associated with high mortality if managed conservatively. Open surgery is associated with significant morbidity and mortality especially when performed for rupture. Endovascular stent coverage after feeding vessel embolization...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574410369387
更新日期:2010-08-01 00:00:00
abstract:PURPOSE:To evaluate the effect of balloon-occluded transvenous obliteration (BRTO) on the model for end-stage liver disease (MELD) and the Child-Pugh (C-P) score and their individual components. METHODS:A retrospective review of patients undergoing only BRTO without transjugular intrahepatic portosystemic shunt was pe...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574413485646
更新日期:2013-05-01 00:00:00
abstract:PURPOSE:This study tests an existing Vascular Biochemistry and Haematology Outcome Model (VBHOM) on independent data and presents further refinements to the model. METHODS:Data from 306 patients who underwent lower limb amputation over a 4-year period were collated. Urea, creatinine, sodium, potassium, hemoglobin, whi...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412445600
更新日期:2012-07-01 00:00:00
abstract:INTRODUCTION:Most common tumor extending into the inferior vena cava (IVC) are renal carcinomas, such extension have been noted in nearly one-fifth of tumors. Tumor thrombectomy improves the prognosis of patients including those with extension of tumor as far as supra hepatic vena cava. In contrast, if radical nephrect...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574419831834
更新日期:2019-05-01 00:00:00
abstract::Strategies developed by vascular surgeons to establish an endovascular program and the 5-year results of the program are reported. In 1994, the operating room was chosen as the site for the endovascular suite. With this strategy, vascular surgeons would be able to 1) govern appropriate indications for intervention, 2)...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440203600104
更新日期:2002-01-01 00:00:00
abstract::Since the outbreak of the COVID-19 pandemic, increasing evidence suggests that infected patients present a high incidence of thrombotic complications. We report a 67-year-old-woman admitted for severe acute respiratory syndrome coronavirus 2 infection. Chest CT images showed bilateral ground glass opacities, bilateral...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574420966106
更新日期:2020-10-09 00:00:00
abstract:OBJECTIVE:The optimal antithrombotic regimen in peripheral arterial disease (PAD) is not known, leading to significant variations in antithrombotic treatment protocols in randomized trials and clinical practice. In device trials, antithrombotic regimens in patients receiving peripheral vascular interventions have not b...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
doi:10.1177/1538574419836316
更新日期:2019-05-01 00:00:00
abstract::Aneurysms of the superior mesenteric artery (SMA) are an uncommon but lethal entity, which must be treated expeditiously to avoid mortality and high incidence of ischemic small bowel complications. In the past 7 years the authors have treated 4 patients with a variety of types of aneurysms involving the SMA and its br...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440303700108
更新日期:2003-01-01 00:00:00
abstract:PURPOSE:The snorkel technique is commonly used to preserve renal arteries in juxta renal aneurysm during endovascular repair. Herein, we present a patient who underwent bifurcated endograft implantation with snorkel technique for inferior mesenteric artery (IMA) in order to preserve the major source of bowel circulatio...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574418758597
更新日期:2018-04-01 00:00:00
abstract:PURPOSE:The purpose of this study was to evaluate the safety and efficacy of preoperative percutaneous n-butyl cyanoacrylate (nBCA) embolization of venous malformations in children. MATERIAL AND METHODS:Clinical data were retrospectively reviewed in children who underwent embolization using nBCA followed by resection ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574418762192
更新日期:2018-05-01 00:00:00
abstract::Leiomyosarcoma of the inferior vena cava (IVC) is a rare tumor of mesenchymal origin, occurring most frequently in middle-aged women. Insidious complaints delay diagnosis, prognosis is poor, and the only curative modality remains an aggressive surgical resection yielding clear margins of disease. Commonly, radical tum...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412460102
更新日期:2012-11-01 00:00:00
abstract::A fistula between the iliac artery and a bladder pouch is a rare but potentially life-threatening condition. In 3 patients presenting with massive hematuria after urinary diversion, an iliac artery pseudoaneurysm was found on imaging studies. These pseudoaneurysms were considered to be associated with a fistula betwee...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574413500724
更新日期:2013-11-01 00:00:00
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journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574407307404
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND/PURPOSE:This study analyzes the safety and efficacy of carotid angioplasty/stenting (CAS) with embolic protection devices in high surgical risk (HSR) patients. PATIENT POPULATION/METHODS: This study includes 100 consecutive HSR patients, who were followed prospectively, and had carotid duplex ultrasounds at ...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574408318477
更新日期:2008-10-01 00:00:00
abstract::This investigation was designed to determine whether minimally invasive radiofrequency or laser ablation of the saphenous vein corrects the hemodynamic impact and clinical symptoms of chronic venous insufficiency (CVI) in CEAP clinical class 3-6 patients with superficial venous reflux. Patients with CEAP clinical clas...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440604000206
更新日期:2006-03-01 00:00:00
abstract::The objective was to evaluate our results on functional outcome for both through-knee amputations and above-knee amputations. Functional outcome was measured using the Special Interest Group in Amputee Medicine score, which focuses on walking distance and use of prosthesis. From 1997 to 2006, 39 through-knee amputatio...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574408316914
更新日期:2008-10-01 00:00:00
abstract::Insufficient renal artery length for renal sympathetic denervation (RDN) is defined as having a main renal artery shorter than 20 mm in length. Such an anatomy is considered a contraindication for most of the currently available endovascular RDN devices. The concern stems from the need to distribute the ablation point...
journal_title:Vascular and endovascular surgery
pub_type: 信件
doi:10.1177/1538574416629564
更新日期:2016-01-01 00:00:00
abstract:PURPOSE:Mycotic aortic aneurysms are rare but are associated with high morbidity and mortality due to their propensity for rupture. Traditional therapy consists of open surgical repair with resection and aortic reconstruction or extra-anatomic bypass combined with long-term antibiotic therapy. CASE REPORT:An 85-year-o...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574411418007
更新日期:2011-11-01 00:00:00
abstract:INTRODUCTION:Despite advances of endovascular interventions, bypass surgery remains the gold standard for treatment of long and complex arterial occlusions in the lower limb. Autologous vein is regarded superior to other options. As the graft of first choice, the great saphenous vein (GSV) is often not available due to...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574420980610
更新日期:2021-01-22 00:00:00
abstract::Vascular disease associated with diabetes mellitus is a major cause of morbidity and mortality and is increasing in the United States. It is now recognized that oxidative stress plays a substantial role in the underlying vascular pathology of several diseases, including hypertension and diabetes. In diabetes, there is...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章,评审
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更新日期:2008-08-01 00:00:00
abstract::The fate of popliteal artery aneurysms after ligation and bypass is believed to be relatively innocuous. The patient presented in this report, however, experienced spontaneous rupture of a popliteal aneurysm 11 years after ligation and bypass. Magnetic resonance angiography was used to establish the diagnosis of ruptu...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/153857440403800613
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVES:To review immediate results, patency rates, hemodynamic success, and incidence of concomitant procedures with external iliac artery stenting (EIAS). METHODS:Demographic features, category and clinical grade, Trans-Atlantic Inter-Society Consensus II classification lesion type, pre- and postprocedure ankle-b...
journal_title:Vascular and endovascular surgery
pub_type: 杂志文章
doi:10.1177/1538574412442400
更新日期:2012-04-01 00:00:00