The expanded role of extracellular matrix patch in malignant and non-malignant chest wall reconstruction in thoracic surgery.

Abstract:

OBJECTIVES:The extracellular matrix (XCM Biologic Tissue Matrix) is a non-cross-linked 3D patch derived from porcine dermis. Once implanted, it is infiltrated by recipient's cells and becomes incorporated in the repair. Here, we report the first series of using this device for chest wall reconstruction. METHODS:The XCM Biologic Tissue Matrix was utilized to provide the restoration of chest wall defects. It was used either alone or in conjunction with the Synthes titanium system to provide additional support. The decision was made intraoperatively. RESULTS:Since April 2010, 21 (12 females) patients received the device. Average age at operation was 47 ± 17 years. Eleven (52%) patients had the patch inserted alone, while the remaining 10 received it in combination with another implantable medical device. The biological tissue matrix was used to reconstruct chest wall defects in cancer involving chest wall (n = 9), chest wall deformity (n = 6), chest wall hernia (n = 5) and chest wall repair following empyema drainage (n = 1). Complications were witnessed in 3 patients receiving the combined XCM and Synthes bar mechanisms; infection (n = 2) and bar displacement and infection (n = 1). CONCLUSIONS:The XCM patch can be safely used to provide the strength required for chest wall reconstruction and to replace previously infected reconstructions.

authors

George RS,Kostopanagiotou K,Papagiannopoulos K

doi

10.1093/icvts/ivt473

subject

Has Abstract

pub_date

2014-03-01 00:00:00

pages

335-9

issue

3

eissn

1569-9293

issn

1569-9285

pii

ivt473

journal_volume

18

pub_type

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