What is the optimal dose of aspirin after discharge following coronary bypass surgery.

Abstract:

:A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was, what is the optimal dose of aspirin post cardiac surgery that should be given to prevent graft occlusion and prolong survival. Altogether, 114 papers were found from Medline and 59 papers were found from the Cochrane Central Register of Controlled Trials using the reported search, of which seven presented the best evidence to answer the clinical question. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes, results, and study weaknesses of these papers are tabulated. We conclude that best evidence suggests that 325 mg optimally improves vein graft survival and mortality, and does not cause an increase in complications compared to lower doses.

authors

Dunning J,Das S

doi

10.1016/S1569-9293(03)00202-0

subject

Has Abstract

pub_date

2003-12-01 00:00:00

pages

427-30

issue

4

eissn

1569-9293

issn

1569-9285

pii

2/4/427

journal_volume

2

pub_type

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