18F-FDG PET/CT for staging and detection of extramedullary organ involvement in chronic myelomonocytic leukemia.

Abstract:

:Chronic myelomonocytic leukemia (CMML) is a rare hematologic malignancy characterized by the accumulation of monocytes in the blood and bone marrow, dysplastic hematopoiesis, and potential leukemic involvement of organs. We report a case of leukemic involvement of cervical lymph nodes detected by 18F-FDG PET/CT. A 53-year-old woman with CMML and newly diagnosed cervical lymphadenopathy underwent whole-body PET/CT for evaluation of extramedullary disease. PET demonstrated marked tracer uptake in cervical lymph nodes. Histopathological evaluation revealed leukemic involvement. 18F-FDG PET/CT is a valuable tool enabling sensitive staging of CMML, particularly in case of extramedullary organ involvement.

journal_name

Clin Nucl Med

authors

Derlin T,Clauditz TS,Bannas P

doi

10.1097/RLU.0b013e3182a77c99

subject

Has Abstract

pub_date

2014-09-01 00:00:00

pages

811-2

issue

9

eissn

0363-9762

issn

1536-0229

journal_volume

39

pub_type

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