Plantar fibromatosis--topical review.

Abstract:

:Morbus Ledderhose is a rare hyperproliferative disease of the plantar fascia, leading to the formation of nodules. Its origin is unknown. No causal therapy is available, and treatment remains symptomatic. Various therapeutic strategies to alleviate symptoms are available and are adapted to the severity of the disease. In early stages, conservative therapy including nonpharmacological, physical, and pharmacological treatments is applied. If the disease progresses, irradiation of the plantar surface, injections of steroids, shock wave therapy, and partial or complete fasciectomy as an ultimate therapy may be indicated. Novel experimental treatment options including application of fibrinolytic agents are currently being tested, but no controlled, randomized long-term studies are available. This review aims to provide a systematic overview of current established procedures and outlines novel experimental strategies for the treatment of morbus Ledderhose, including future avenues to treat this rare disease.

journal_name

Foot Ankle Int

authors

Veith NT,Tschernig T,Histing T,Madry H

doi

10.1177/1071100713505535

subject

Has Abstract

pub_date

2013-12-01 00:00:00

pages

1742-6

issue

12

eissn

1071-1007

issn

1944-7876

pii

1071100713505535

journal_volume

34

pub_type

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