Abstract:
OBJECTIVE:In a previous polysomnographic cross-sectional study we found a significant relationship between sleep disorders and multiple sclerosis (MS) related fatigue. The purpose of this open follow-up observation was to compare the impact of treatment of sleep disorders on MS related fatigue measured with the Modified Fatigue Impact Scale (MFIS). METHODS:Non-randomized follow-up observation: treated versus untreated patients, subgroups according to compliance with sleep medical treatment recommendations (univariate, multivariate analysis, multiple logistic regression). 66 MS patients were followed after polysomnography, 49 patients with relevant sleep disorders and 17 without. RESULTS:Mean MFIS scores decreased from 41.2 to 26.2 (p=0.025) in patients with good compliance (GC; n=18), from 42.4 to 32.1 (p=0.12) in patients with moderate compliance (MC; n=12), and from 41.6 to 35.5 (p=0.17) in non-compliant patients (NC; n=17). Mean MFIS values increased in patients without sleep disorders from 22.9 to 25.4 (NSD; n=12, p=0.56). In multiple logistic regression, treatment of sleep disorders predicted decrease of MFIS-values (GC versus NSD odds ratio 13.4; p=0.015; 95% confidence interval (CI) 1.7-107.2, MC versus NSD odds ratio 13.8; p=0.028; 95% CI 1.3-143.3). CONCLUSIONS:Sleep medical treatment may improve MS related fatigue when patients adhere to treatment recommendations.
journal_name
Clin Neurol Neurosurgjournal_title
Clinical neurology and neurosurgeryauthors
Veauthier C,Gaede G,Radbruch H,Gottschalk S,Wernecke KD,Paul Fdoi
10.1016/j.clineuro.2013.05.018subject
Has Abstractpub_date
2013-09-01 00:00:00pages
1826-30issue
9eissn
0303-8467issn
1872-6968pii
S0303-8467(13)00174-1journal_volume
115pub_type
杂志文章abstract:OBJECTIVES:Neurologists have continually led the assessment and management of Acute Ischemic Stroke(AIS) by use of IV-rtPA, anti-platelet therapy, antihypertensives, and other pharmacologic agents. Since the advent of mechanical thrombectomy(MT) and its proven efficacy, neurovascular surgeons(NS) are playing an increas...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2018.02.033
更新日期:2018-05-01 00:00:00
abstract:OBJECTIVE:The objective of this study was to evaluate the prognostic significance of neurological manifestations in falciparum malaria. METHODS:We analyzed adult patients with malaria admitted from 2001 to 2003, diagnosed by asexual forms of Plasmodium falciparum in peripheral blood films and identified cases of malar...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2010.09.010
更新日期:2011-02-01 00:00:00
abstract::A review is given of the aetiology and possible treatment of acquired (non-congenital), blepharoptosis, which is a common but not specific sign of neurological disease. The diagnostic categories of upper eyelid drooping are scheduled as (a) pseudo-ptosis due to a local process or overactivity of eye closure, including...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/0303-8467(95)00087-9
更新日期:1996-02-01 00:00:00
abstract:OBJECTIVE:Mean platelet volume (MPV) determined shortly after the onset of acute ischemic stroke represents the pre-stroke values. Data on its relationship to stroke severity/outcome have been conflicting. We related MPV to infarct volume on CT brain scans and risk of death/dependence 7 days and 3 months post-stroke. ...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2009.04.002
更新日期:2009-09-01 00:00:00
abstract::Stereotactic implantation of depth electrodes for surgical evaluation of drug-resistant epilepsy is the technique of choice in many centers across the world. Historically, the choice of depth versus subdural electrodes has been largely dependent on the training of epileptologists and epilepsy surgeons in light of thei...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.clineuro.2019.105640
更新日期:2020-02-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to compare the muscle activation feature of vastus medialis obliquus (VMO) and vastus lateralis (VL) between the osteoarthritic knee patients with patellar lateral subluxation (Group 1B) and without patellar lateral subluxation (Group 1A). METHODS:Isokinetic muscle strength of the kn...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/S0303-8467(15)30009-3
更新日期:2015-02-01 00:00:00
abstract::A 33-year-old woman, with a 7-year clinical history of invasive thymoma treated at ages 26 and 30 years by thymectomy and radiation, presented with a generalized convulsion and loss of consciousness. Following the seizure there was no neurological deficit and normal tendon reflexes. Magnetic resonance imaging (MRI) of...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2006.09.007
更新日期:2007-02-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of intensive blood pressure control on progressive intracerebral hemorrhage and outcome in patients with high blood pressure and intracerebral hemorrhage. PATIENTS AND METHODS:A retrospective study was conducted recruiting 659 patients with acute hemorrhagic stroke between Jan. 2012...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2019.02.021
更新日期:2019-05-01 00:00:00
abstract:BACKGROUND:Hypertension is the most common cause of intracerebral haemorrhages (ICHs), yet the short-term impact factors associated with hypertensive intracerebral haemorrhages (HICHs) in patients who undergo different surgical treatments are still unknown. MATERIALS AND METHODS:All consecutive patients with acute HIC...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2016.08.023
更新日期:2016-11-01 00:00:00
abstract:OBJECTIVE:Spinal cord stimulation has been proven highly effective in the treatment of Complex Regional Pain Syndrome (CRPS). The definitive implantation of a neurostimulator is usually preceded by a therapeutic test (trial), which has the purpose of identifying whether the patient would respond positively to neuromodu...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2018.06.014
更新日期:2018-08-01 00:00:00
abstract::Spontaneous closures of dural arteriovenous fistulas (dAVFs) are rare. We present spontaneous occlusion of dAVFs in 3 cases (one type IIa dAVF, one type IIb and one type III). Patients were 3 males with a mean age of 55 years (range 45-61). For two patients, the dAVF was revealed by hemorrhage. No head trauma was reco...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2012.10.006
更新日期:2013-07-01 00:00:00
abstract::We studied 200 female patients with multiple sclerosis (MS) to investigate whether pregnancy after the onset of disease influences long term disability. As an index of progression, we used the time between disease onset and wheelchair dependence. Patients who had at least one pregnancy after onset were wheelchair depe...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/0303-8467(94)90027-2
更新日期:1994-02-01 00:00:00
abstract::A 7-year-old girl presented with focal seizures without symptoms of raised intracranial tension. Routine histological, immunocytochemical and ultrastructural methods revealed a desmoplastic low grade cerebral astrocytoma. Follow up for 2 years after biopsy did not show recruitment of neurological symptoms or signs. Bi...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/0303-8467(94)00051-7
更新日期:1995-02-01 00:00:00
abstract::A male patient came to our clinic because of a continuous up and down movement of his right testis, which was present even during sleep. The nature and localization of the unilateral rhythmic cremasteric activity is investigated by electrophysiological methods. Investigations of the cremasteric muscles and genitofemor...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2010.05.013
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:Chronic subdural haematoma is a disease of the elderly and surgery in these patients carries a much higher risk. The common surgical procedures for chronic subdural haematoma include twist drill craniostomy, burr hole evacuation or craniotomy. The aim of this study was to analyse the results of twist drill cr...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2008.04.013
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVES:Device subsidence is a well-known complication following cervical disc arthroplasty. Its occurrence has been closely tied with the endplate-implant contact interface. But current literature on the geometry of cervical endplate is very scarce. The aim of this anatomical investigation was to analyze geometry o...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2016.01.027
更新日期:2016-03-01 00:00:00
abstract::Two patients are described who survived respectively 33 and 21 years after partial surgical excision of a posterior fossa ependymoma and who at the time of autopsy were proven to harbor persistent tumour tissue in the same location. ...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/s0303-8467(75)80048-5
更新日期:1975-01-01 00:00:00
abstract:OBJECTIVE:Clear cell meningioma (CCM) is a rare disease, and controversy about treatment and prognosis of CCMs still exists. We aimed to clarify the natural history, radiological features, histological characteristics, management and prognosis of intracranial CCMs. PATIENTS AND METHODS:We performed a retrospective stu...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2018.10.014
更新日期:2018-12-01 00:00:00
abstract::Seven cases are presented of recurrent ventricular catheter obstruction, an infrequent but serious problem in the management of hydrocephalus. Plugging of the catheter was caused by detritus rather than by choroid plexus. A retrospective analysis of 214 shunt revisions indicated that obstruction both by detritus and b...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/0303-8467(81)90001-9
更新日期:1981-01-01 00:00:00
abstract:BACKGROUND:The National Institute for Health and Clinical Excellence (NICE) guidelines for multiple sclerosis (MS) recommend the time from initial presentation to first neurological evaluation to be no longer than 6 weeks, and a further 6 weeks until any necessary investigations are completed. The aim of this study was...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2013.09.025
更新日期:2013-12-01 00:00:00
abstract::Tuberculosis is still a major cause of serious illness in many parts of the world. CNS involvement has frequently been found secondary to tuberculosis elsewhere in the body, particularly the lungs. The disease manifests itself as meningitis, tuberculoma and/or spinal tuberculosis. The presence of tuberculosis elsewher...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/0303-8467(92)90014-t
更新日期:1992-01-01 00:00:00
abstract::Both migraine and vertigo are common complaints. Although they may coincide by chance, there is growing evidence for a clinical entity of recurrent vestibular symptoms related to migraine. This syndrome implies a possible causal relationship although the pathophysiology of migraine-related vertigo has not been fully e...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.clineuro.2004.07.003
更新日期:2005-02-01 00:00:00
abstract::Moyamoya is the disease which involves the terminal portions of the internal carotid or origins of the middle or anterior cerebral arteries. The posterior communicating arteries are also involved, but not the vertebrals or the basilar artery. The disease occurs more commonly in females than males and it has two age pe...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/s0303-8467(97)00073-5
更新日期:1997-10-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to clarify the relationship between ischaemic symptoms during the early postoperative period in patients with moyamoya disease and changes in the cerebellar asymmetry index (AI), a parameter used to quantitatively identify crossed cerebellar diaschisis (CCD). PATIENTS AND METHODS:We...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2020.106090
更新日期:2020-10-01 00:00:00
abstract::Increasing experience with intensive monitoring of patients with intractable seizures has shown that a significant number of patients presents with pseudoseizures (psychogenic seizures). While in a majority of the patients differential diagnosis should be obvious, in some patients diagnostic error may occur. This is t...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/0303-8467(93)90085-u
更新日期:1993-03-01 00:00:00
abstract:INTRODUCTION:Traumatic brain injury is a silent epidemic with major impacts on national productivity as it affects the economically productive age group. Bilateral injuries are usually severe with no clearly defined predictors of outcome as per current available literature. METHODS:We retrospectively assessed 102 cons...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2020.106017
更新日期:2020-09-01 00:00:00
abstract:BACKGROUND:Little information is available on Asian patients over 80 years with stroke. We aimed to investigate characteristics of the very elderly ischemic stroke hospitalized patients in China. METHODS:We prospectively enrolled consecutive patients with acute ischemic stroke from March, 2002 to October, 2008 into th...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2011.01.005
更新日期:2011-07-01 00:00:00
abstract::We report a 35-year-old woman with painful muscle cramps in both legs, this being the only symptom of the syndrome of continuous muscle fibre activity. Diagnosis was confirmed by electromyography during sleep. ...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/0303-8467(90)90035-4
更新日期:1990-01-01 00:00:00
abstract:OBJECTIVE:Acute carbon monoxide (CO) poisoning poses a significant threat to the central nervous system. It can cause brain injury and diverse neurological deficits including persistent neurological sequelae (PNS) and delayed neurological sequelae (DNS). The study aimed to investigate the long-term impacts of acute CO ...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2014.01.005
更新日期:2014-04-01 00:00:00
abstract:OBJECTIVE:Thromboembolic events, seizures, neurologic symptoms and adverse effects from corticosteroids and chemotherapies are frequent clinical complications seen in Glioblastoma (GB) patients. The exact impact these have on dismal patient outcome has not been fully elucidated. We aimed at assessing treatment associat...
journal_title:Clinical neurology and neurosurgery
pub_type: 杂志文章
doi:10.1016/j.clineuro.2015.01.006
更新日期:2015-07-01 00:00:00